| Disease ID | Disease name | Source of annotation with APOC3 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS607432 | LISSENCEPHALY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 9 | CDK5, APOC3, PAFAH1B1, ARX, DCX, LAMB1, TUBA1A, RELN, KATNB1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| PPAR signaling pathway | hsa03320 | 6.56 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Lipoprotein metabolism | R-HSA-174824 | 8.23 |
| Visual phototransduction | R-HSA-2187338 | 6.44 |
| Lipid digestion, mobilization, and transport | R-HSA-73923 | 7.2 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Retinoid metabolism and transport | R-HSA-975634 | 7.59 |
| HDL-mediated lipid transport | R-HSA-194223 | 9.08 |
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| Chylomicron-mediated lipid transport | R-HSA-174800 | 9.18 |
| GO term | GO ID | GO IC |
|---|---|---|
| sterol binding | GO:0032934 | 5.98 |
| cholesterol binding | GO:0015485 | 6.1 |
| alcohol binding | GO:0043178 | 5.53 |
| lipoprotein particle receptor binding | GO:0070325 | 6.65 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| phospholipid binding | GO:0005543 | 3.91 |
| GO:0070653 | 8.64 | |
| lipid binding | GO:0008289 | 3.26 |
| small molecule binding | GO:0036094 | 1.89 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| steroid binding | GO:0005496 | 5.24 |
| enzyme inhibitor activity | GO:0004857 | 3.78 |
| lipase inhibitor activity | GO:0055102 | 6.85 |
| receptor binding | GO:0005102 | 2.43 |
| molecular function regulator | GO:0098772 | 2.51 |