| Disease ID | Disease name | Source of annotation with CALR | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 254450 | MYELOFIBROSIS | OMIM | link to OMIM | 4 | SH2B3, JAK2, MPL, CALR |
| PS187950 | THROMBOCYTHEMIA | OMIM | link to OMIM | 5 | SH2B3, JAK2, MPL, THPO, CALR |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Protein processing in endoplasmic reticulum | hsa04141 | 5.35 |
| Chagas disease (American trypanosomiasis) | hsa05142 | 5.99 |
| HTLV-I infection | hsa05166 | 4.59 |
| Phagosome | hsa04145 | 5.27 |
| Antigen processing and presentation | hsa04612 | 6.04 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 11.98 |
| Immune System | R-HSA-168256 | 2.37 |
| Influenza Infection | R-HSA-168254 | 5.86 |
| Influenza Life Cycle | R-HSA-168255 | 5.92 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 6.64 |
| Post-translational protein modification | R-HSA-597592 | 4.54 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| Disease | R-HSA-1643685 | 3.33 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 5.88 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.08 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 6.1 |
| Infectious disease | R-HSA-5663205 | 4.47 |
| Virus Assembly and Release | R-HSA-168268 | 11.98 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.52 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
| ATF6-alpha activates chaperone genes | R-HSA-381183 | 9.66 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.28 |
| Vesicle-mediated transport | R-HSA-5653656 | 4.33 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 6.56 |
| ATF6-alpha activates chaperones | R-HSA-381033 | 9.4 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 8.73 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 10.4 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 5.38 |
| GO term | GO ID | GO IC |
|---|---|---|
| ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
| androgen receptor binding | GO:0050681 | 6.07 |
| carbohydrate binding | GO:0030246 | 4.17 |
| enzyme binding | GO:0019899 | 2.27 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| zinc ion binding | GO:0008270 | 2.66 |
| nucleic acid binding | GO:0003676 | 1.44 |
| DNA binding | GO:0003677 | 1.92 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| glycoprotein binding | GO:0001948 | 5.11 |
| cation binding | GO:0043169 | 1.4 |
| peptide binding | GO:0042277 | 4.22 |
| transition metal ion binding | GO:0046914 | 2.48 |
| chaperone binding | GO:0051087 | 5.34 |
| unfolded protein binding | GO:0051082 | 5.13 |
| ion binding | GO:0043167 | 1.36 |
| complement component C1q binding | GO:0001849 | 7.79 |
| complement binding | GO:0001848 | 6.79 |
| calcium ion binding | GO:0005509 | 3.17 |
| protein complex binding | GO:0032403 | 3.09 |
| iron ion binding | GO:0005506 | 4.65 |
| metal ion binding | GO:0046872 | 1.41 |
| opsonin binding | GO:0001846 | 7.34 |
| integrin binding | GO:0005178 | 5.07 |
| steroid hormone receptor binding | GO:0035258 | 5.32 |
| amide binding | GO:0033218 | 4.14 |
| poly(A) RNA binding | GO:0044822 | 2.69 |
| nuclear hormone receptor binding | GO:0035257 | 4.7 |
| hormone receptor binding | GO:0051427 | 4.57 |
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| hormone binding | GO:0042562 | 5.53 |
| ubiquitin protein ligase binding | GO:0031625 | 4.17 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| protein binding involved in protein folding | GO:0044183 | 7.1 |
| RNA binding | GO:0003723 | 2.36 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| mRNA binding | GO:0003729 | 4.68 |
| binding | GO:0005488 | 0.18 |