Disease ID | Disease name | Source of annotation with EDC3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS249500 | MENTAL RETARDATION, AUTOSOMAL RECESSIVE | OMIM, HUMSAVAR | link to OMIM | 31 | ADAT3, NDST1, GPT2, PIGG, FMN2, TTI2, PGAP1, HNMT, EDC3, NSUN2, KPTN, GRIK2, TAF2, KIAA1033, MED23, PRSS12, FBXO31, LINS1, HERC2, CC2D1A, METTL23, TUSC3, ST3GAL3, TECR, CRADD, MAN1B1, SLC6A17, ANK3, CRBN, TRAPPC9, LMAN2L |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
RNA degradation | hsa03018 | 6.48 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Gene Expression | R-HSA-74160 | 2.72 |
Deadenylation-dependent mRNA decay | R-HSA-429914 | 7.37 |
mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 9.08 |
GO term | GO ID | GO IC |
---|---|---|
hydrolase activity | GO:0016787 | 1.9 |
nucleic acid binding | GO:0003676 | 1.44 |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | GO:0016893 | 5.83 |
nuclease activity | GO:0004518 | 4.33 |
organic cyclic compound binding | GO:0097159 | 1.05 |
poly(A) RNA binding | GO:0044822 | 2.69 |
ribonuclease activity | GO:0004540 | 5.04 |
endoribonuclease activity | GO:0004521 | 5.58 |
hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
catalytic activity | GO:0003824 | 1.05 |
endoribonuclease activity, producing 5'-phosphomonoesters | GO:0016891 | 6.02 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
endonuclease activity | GO:0004519 | 4.78 |
mRNA binding | GO:0003729 | 4.68 |
phosphodiesterase decapping endonuclease activity | GO:1990174 | 9.74 |
heterocyclic compound binding | GO:1901363 | 1.06 |
identical protein binding | GO:0042802 | 2.63 |
RNA binding | GO:0003723 | 2.36 |