| Disease ID | Disease name | Source of annotation with IFNAR2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 616669 | IMMUNODEFICIENCY 45 | OMIM | link to OMIM | 1 | IFNAR2 |
| 610424 | HEPATITIS B VIRUS, SUSCEPTIBILITY TO | ClinVar, OMIM | link to OMIM | 3 | IFNAR2, IFNGR1, IL10RB |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
| Toll-like receptor signaling pathway | hsa04620 | 6.0 |
| Jak-STAT signaling pathway | hsa04630 | 5.44 |
| Herpes simplex infection | hsa05168 | 5.08 |
| Measles | hsa05162 | 5.6 |
| Osteoclast differentiation | hsa04380 | 5.64 |
| Influenza A | hsa05164 | 5.21 |
| Hepatitis C | hsa05160 | 5.68 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Interferon Signaling | R-HSA-913531 | 4.95 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| Regulation of IFNA signaling | R-HSA-912694 | 8.34 |
| Immune System | R-HSA-168256 | 2.37 |
| Interferon alpha/beta signaling | R-HSA-909733 | 6.04 |
| GO term | GO ID | GO IC |
|---|---|---|
| signal transducer activity | GO:0004871 | 2.28 |
| type I interferon binding | GO:0019962 | 9.05 |
| interferon binding | GO:0019961 | 8.64 |
| molecular transducer activity | GO:0060089 | 2.32 |
| cytokine binding | GO:0019955 | 5.21 |
| interleukin-20 binding | GO:0042015 | 8.13 |
| enzyme binding | GO:0019899 | 2.27 |
| interferon receptor activity | GO:0004904 | 8.13 |
| protein kinase binding | GO:0019901 | 3.44 |
| kinase binding | GO:0019900 | 3.32 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| receptor activity | GO:0004872 | 2.32 |
| protein binding | GO:0005515 | 0.46 |
| signaling receptor activity | GO:0038023 | 2.49 |
| cytokine receptor activity | GO:0004896 | 5.24 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| type I interferon receptor activity | GO:0004905 | 9.05 |
| binding | GO:0005488 | 0.18 |