| Disease ID | Disease name | Source of annotation with IFNGR1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 607948 | MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO | OMIM | link to OMIM | 11 | IFNG, TIRAP, CD209, IFNGR1, MC3R, CISH, CCL2, IRGM, SLC11A1, TLR2, SP110 |
| 209950 | IMMUNODEFICIENCY 27A | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | IFNGR1 |
| 610424 | HEPATITIS B VIRUS, SUSCEPTIBILITY TO | ClinVar, OMIM | link to OMIM | 3 | IFNAR2, IFNGR1, IL10RB |
| 615978 | IMMUNODEFICIENCY 27B | OMIM | link to OMIM | 1 | IFNGR1 |
| 600263 | HELICOBACTER PYLORI INFECTION, SUSCEPTIBILITY TO | OMIM | link to OMIM | 2 | IFNGR1, PTPRZ1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Salmonella infection | hsa05132 | 6.29 |
| Inflammatory bowel disease (IBD) | hsa05321 | 6.43 |
| Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
| Toxoplasmosis | hsa05145 | 5.71 |
| Jak-STAT signaling pathway | hsa04630 | 5.44 |
| Chagas disease (American trypanosomiasis) | hsa05142 | 5.99 |
| Influenza A | hsa05164 | 5.21 |
| Leishmaniasis | hsa05140 | 6.32 |
| Tuberculosis | hsa05152 | 5.17 |
| Herpes simplex infection | hsa05168 | 5.08 |
| Measles | hsa05162 | 5.6 |
| Osteoclast differentiation | hsa04380 | 5.64 |
| HIF-1 signaling pathway | hsa04066 | 5.9 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Interferon Signaling | R-HSA-913531 | 4.95 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| Regulation of IFNG signaling | R-HSA-877312 | 9.18 |
| Interferon gamma signaling | R-HSA-877300 | 5.67 |
| Immune System | R-HSA-168256 | 2.37 |
| GO term | GO ID | GO IC |
|---|---|---|
| binding | GO:0005488 | 0.18 |
| signaling receptor activity | GO:0038023 | 2.49 |
| signal transducer activity | GO:0004871 | 2.28 |
| cytokine binding | GO:0019955 | 5.21 |
| interleukin-20 binding | GO:0042015 | 8.13 |
| molecular transducer activity | GO:0060089 | 2.32 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| receptor activity | GO:0004872 | 2.32 |
| protein binding | GO:0005515 | 0.46 |
| interferon receptor activity | GO:0004904 | 8.13 |
| interferon-gamma receptor activity | GO:0004906 | 9.05 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| cytokine receptor activity | GO:0004896 | 5.24 |