Gene table of ORC1 : origin recognition complex subunit 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with ORC1OMIM linkNumber of associated genesgenes
PS224690MEIER-GORLIN SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 6GMNN, ORC1, CDT1, ORC4, CDC6, ORC6

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Annotation of the gene ORC1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Cell cyclehsa041105.68
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Activation of the pre-replicative complexR-HSA-689628.08
Cell Cycle, MitoticR-HSA-692784.16
Cell CycleR-HSA-16401703.89
Association of licensing factors with the pre-replicative complexR-HSA-692989.08
Assembly of the ORC complex at the origin of replicationR-HSA-6861610.4
Switching of origins to a post-replicative stateR-HSA-690526.85
DNA ReplicationR-HSA-693066.25
Cell Cycle CheckpointsR-HSA-696205.64
Orc1 removal from chromatinR-HSA-689496.85
CDT1 association with the CDC6:ORC:origin complexR-HSA-688277.12
Synthesis of DNAR-HSA-692396.37
E2F-enabled inhibition of pre-replication complex formationR-HSA-1135079.66
Mitotic G1-G1/S phasesR-HSA-4532795.91
Assembly of the pre-replicative complexR-HSA-688676.92
DNA Replication Pre-InitiationR-HSA-690026.62
G2/M CheckpointsR-HSA-694816.46
G1/S TransitionR-HSA-692066.21
G1/S-Specific TranscriptionR-HSA-692058.89
CDC6 association with the ORC:origin complexR-HSA-686899.52
S PhaseR-HSA-692426.02
Regulation of DNA replicationR-HSA-693046.75
Activation of ATR in response to replication stressR-HSA-1761877.77
Removal of licensing factors from originsR-HSA-693006.81
E2F mediated regulation of DNA replicationR-HSA-1135107.94
M/G1 TransitionR-HSA-688746.62
Associated GO terms for Molecular function
GO termGO IDGO IC
purine ribonucleoside triphosphate bindingGO:00356392.22
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
nucleoside bindingGO:00018822.21
nucleotide bindingGO:00001661.96
purine nucleoside bindingGO:00018832.22
ribonucleoside bindingGO:00325492.22
purine nucleotide bindingGO:00170762.19
ATP bindingGO:00055242.43
small molecule bindingGO:00360941.89
adenyl nucleotide bindingGO:00305542.4
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
adenyl ribonucleotide bindingGO:00325592.41
protein bindingGO:00055150.46
purine ribonucleotide bindingGO:00325552.2
chromatin bindingGO:00036823.64
purine ribonucleoside bindingGO:00325502.22
ribonucleotide bindingGO:00325532.19