Gene table of ORC6 : origin recognition complex subunit 6

Gene-disease associations table

Disease IDDisease nameSource of annotation with ORC6OMIM linkNumber of associated genesgenes
PS224690MEIER-GORLIN SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 6GMNN, ORC1, CDT1, ORC4, CDC6, ORC6

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Annotation of the gene ORC6

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Cell cyclehsa041105.68
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Assembly of the pre-replicative complexR-HSA-688676.92
Cell Cycle, MitoticR-HSA-692784.16
Cell CycleR-HSA-16401703.89
Assembly of the ORC complex at the origin of replicationR-HSA-6861610.4
Switching of origins to a post-replicative stateR-HSA-690526.85
DNA ReplicationR-HSA-693066.25
Cell Cycle CheckpointsR-HSA-696205.64
Orc1 removal from chromatinR-HSA-689496.85
CDT1 association with the CDC6:ORC:origin complexR-HSA-688277.12
Synthesis of DNAR-HSA-692396.37
E2F-enabled inhibition of pre-replication complex formationR-HSA-1135079.66
Mitotic G1-G1/S phasesR-HSA-4532795.91
Activation of the pre-replicative complexR-HSA-689628.08
DNA Replication Pre-InitiationR-HSA-690026.62
G2/M CheckpointsR-HSA-694816.46
G1/S TransitionR-HSA-692066.21
CDC6 association with the ORC:origin complexR-HSA-686899.52
S PhaseR-HSA-692426.02
Regulation of DNA replicationR-HSA-693046.75
Activation of ATR in response to replication stressR-HSA-1761877.77
Removal of licensing factors from originsR-HSA-693006.81
E2F mediated regulation of DNA replicationR-HSA-1135107.94
M/G1 TransitionR-HSA-688746.62
Associated GO terms for Molecular function
GO termGO IDGO IC
protein bindingGO:00055150.46
organic cyclic compound bindingGO:00971591.05
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06