Gene table of PRKRA : protein activator of interferon induced protein kinase EIF2AK2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PRKRA	OMIM link	Number of associated genes	genes
PS128100	DYSTONIA	ClinVar, OMIM, HUMSAVAR	link to OMIM	18	DRD2, GNAL, ANO3, SLC2A1, KCTD17, HPCA, THAP1, GCH1, PRRT2, ATP1A3, PNKD, PRKRA, COL6A3, TOR1A, CACNA1B, SGCE, TAF1, TUBB4A

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Gene Expression	R-HSA-74160	2.72
Regulatory RNA pathways	R-HSA-211000	6.35
Small interfering RNA (siRNA) biogenesis	R-HSA-426486	9.81
MicroRNA (miRNA) biogenesis	R-HSA-203927	8.46

Associated GO terms for Molecular function

GO term	GO ID	GO IC
binding	GO:0005488	0.18
molecular function regulator	GO:0098772	2.51
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
enzyme regulator activity	GO:0030234	2.85
kinase activity	GO:0016301	2.93
poly(A) RNA binding	GO:0044822	2.69
enzyme binding	GO:0019899	2.27
catalytic activity	GO:0003824	1.05
transferase activity	GO:0016740	1.95
double-stranded RNA binding	GO:0003725	5.58
RNA binding	GO:0003723	2.36
nucleic acid binding	GO:0003676	1.44
organic cyclic compound binding	GO:0097159	1.05
protein dimerization activity	GO:0046983	2.72
protein homodimerization activity	GO:0042803	3.16
heterocyclic compound binding	GO:1901363	1.06
identical protein binding	GO:0042802	2.63
enzyme activator activity	GO:0008047	3.56