Disease table of DYSTONIA OMIM ID: PS128100

Gene-disease associations table

GeneAssociated with DYSTONIA inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
THAP1ClinVar, OMIM, HUMSAVARHGNC link8p11.211PS128100
KCTD17ClinVar, OMIM, HUMSAVARHGNC link22q12.31PS128100
TAF1ClinVar, OMIMHGNC linkXq13.12PS309510, PS128100
CACNA1BClinVar, OMIM, HUMSAVARHGNC link9q34.31PS128100
GCH1ClinVar, OMIM, HUMSAVARHGNC link14q22.22PS128100, 233910
DRD2ClinVarHGNC link11q23.21PS128100
SLC2A1ClinVar, OMIM, HUMSAVARHGNC link1p34.24608885, PS606777, PS128100, 614847
PRRT2ClinVar, OMIM, HUMSAVARHGNC link16p11.23602066, PS128100, PS601764
TOR1AClinVar, OMIM, HUMSAVARHGNC link9q34.111PS128100
PNKDClinVar, OMIM, HUMSAVARHGNC link2q351PS128100
HPCAClinVar, OMIM, HUMSAVARHGNC link1p35.11PS128100
TUBB4AClinVar, OMIM, HUMSAVARHGNC link19p13.32PS128100, PS312080
ANO3ClinVar, OMIM, HUMSAVARHGNC link11p14.21PS128100
GNALClinVar, OMIM, HUMSAVARHGNC link18p11.211PS128100
ATP1A3ClinVar, OMIM, HUMSAVARHGNC link19q13.23601338, PS104290, PS128100
COL6A3ClinVar, OMIM, HUMSAVARHGNC link2q37.33PS158810, PS128100, PS254090
PRKRAClinVar, OMIM, HUMSAVARHGNC link2q31.21PS128100
SGCEClinVar, OMIM, HUMSAVARHGNC link7q21.31PS128100

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By band
Shared bandNumber of genes associated with the diseaseGenes associated with the disease
9q342CACNA1B, TOR1A
By region
Shared regionNumber of genes associated with the diseaseGenes associated with the disease
2q33PNKD, PRKRA, COL6A3
1p32HPCA, SLC2A1
9q32CACNA1B, TOR1A
By arm
Shared armNumber of genes associated with the diseaseGenes associated with the disease
1p2HPCA, SLC2A1
2q3PNKD, PRKRA, COL6A3
9q2CACNA1B, TOR1A
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
112DRD2, ANO3
192ATP1A3, TUBB4A
12HPCA, SLC2A1
23PNKD, PRKRA, COL6A3
92CACNA1B, TOR1A
Transcription Factors (TF) annotation from TRRUST
TFassociated to this disease# regulated genesRegulated genes# regulated genes associated with this diseaseRegulated genes associated with this disease
TAF1YES4SRC, LRIG2, CDKN1A, TBP0
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
DRD2YES2NFKB1, RELA0
SLC2A1YES4ATM, HDAC5, HIF1A, TP530
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
THAP1TAF1No1CSNK2A1
THAP1GCH1No1CSNK2A1
THAP1DRD2No1PAWR
THAP1TOR1ANo1KRTAP10-7
THAP1PNKDNo1APP
THAP1PRKRANo2C1ORF35, RALYL
KCTD17TAF1No2TINF2, TP53
KCTD17HPCANo1TP53
KCTD17TUBB4ANo2TINF2, CUL3
KCTD17ANO3No1RAPGEF2
KCTD17PRKRANo1EIF2AK2
TAF1GCH1No1CSNK2A1
TAF1HPCANo1TP53
TAF1TUBB4ANo1TINF2
TAF1PRKRANo1UBE2I
GCH1PRRT2No1CALML5
DRD2TUBB4ANo1ARRB2
SLC2A1TOR1ANo1CANX
SLC2A1PNKDNo3ILK, STOM, NCSTN
SLC2A1TUBB4ANo1ILK
SLC2A1PRKRANo1COPS6
PNKDTUBB4ANo1ILK
PNKDPRKRANo2TARBP2, DICER1
HPCATUBB4ANo1HAX1
TUBB4AANO3No1HSPA5
TUBB4ACOL6A3No1GAN
TUBB4APRKRANo1SIRT7

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
THAP1DRD2No-1CCL21
TAF1CACNA1BNo-1UBC
TAF1SLC2A1No-3MAX, UBC, EP300
TAF1TUBB4ANo-1UBC
TAF1GNALNo-1UBC
TAF1ATP1A3No-1UBC
CACNA1BDRD2No-17GNGT2, GNG2, GNB5, GNAO1, GNG10, GNG13, GNB2, GNG4, GNAI3, GNG11, GNG5, GNGT1, GNB4, GNG3, GNG12, GNG7, GNG8
CACNA1BSLC2A1No-1UBC
CACNA1BTUBB4ANo-1UBC
CACNA1BGNALNo-4GNAI3, UBC, GNGT1, GNG2
CACNA1BATP1A3No-1UBC
GCH1TUBB4ANo-1HSP90AA1
DRD2TUBB4ANo-1PPP2R1A
DRD2GNALNo-8GNAI3, GNG2, HTR5A, GNGT1, ADORA2A, GNAT3, GNAI1, GNB1
SLC2A1TUBB4ANo-1UBC
SLC2A1GNALNo-2UBC, EDN1
SLC2A1ATP1A3No-1UBC
TUBB4AGNALNo-1UBC
TUBB4AATP1A3No-2UBC, PRKACA
GNALATP1A3No-1UBC

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Dopaminergic synapsehsa047285.693CACNA1B, DRD2, GNAL
Protein digestion and absorptionhsa049746.22COL6A3, ATP1A3
Gap junctionhsa045406.242TUBB4A, DRD2
Bile secretionhsa049766.562ATP1A3, SLC2A1
Calcium signaling pathwayhsa040205.222CACNA1B, GNAL
cAMP signaling pathwayhsa040245.052ATP1A3, DRD2
Insulin secretionhsa049116.182ATP1A3, SLC2A1
Thyroid hormone signaling pathwayhsa049195.822ATP1A3, SLC2A1
Parkinson's diseasehsa050125.592DRD2, GNAL

NET-GE enrichment

Term New enriched termICP valueGenes
Dopaminergic synapse (hsa04728) -5.690.044CACNA1B, DRD2, GNAL
REACTOME pathways annotation: shared terms (no NET-GE enrichment)

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Signal TransductionR-HSA-1625821.784COL6A3, DRD2, GNAL, TUBB4A
Transmembrane transport of small moleculesR-HSA-3825513.793ATP1A3, SLC2A1, ANO3
Signaling by GPCRR-HSA-3727902.682DRD2, GNAL
GPCR downstream signalingR-HSA-3883963.072DRD2, GNAL
Ion channel transportR-HSA-9837125.342ATP1A3, ANO3
MetabolismR-HSA-14307282.342SLC2A1, GCH1
Gene ExpressionR-HSA-741602.722PRKRA, TAF1
Neuronal SystemR-HSA-1123164.822CACNA1B, GNAL
Axon guidanceR-HSA-4224753.932TUBB4A, COL6A3
Transmission across Chemical SynapsesR-HSA-1123155.282CACNA1B, GNAL
Developmental BiologyR-HSA-12667383.482TUBB4A, COL6A3
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.1815ATP1A3, GNAL, GCH1, KCTD17, PRKRA, CACNA1B, TAF1, TOR1A, SLC2A1, THAP1, DRD2, ANO3, HPCA, TUBB4A, PNKD
protein binding (GO:0005515) 0.4615CACNA1B, TOR1A, GCH1, GNAL, KCTD17, PRKRA, ATP1A3, DRD2, SLC2A1, THAP1, TAF1, ANO3, HPCA, TUBB4A, PNKD
organic cyclic compound binding (GO:0097159) 1.0510ATP1A3, GNAL, GCH1, PRKRA, CACNA1B, DRD2, TOR1A, THAP1, TAF1, TUBB4A
heterocyclic compound binding (GO:1901363) 1.069ATP1A3, GNAL, GCH1, PRKRA, CACNA1B, TAF1, TOR1A, THAP1, TUBB4A
catalytic activity (GO:0003824) 1.058ATP1A3, GNAL, TOR1A, PRKRA, TAF1, PNKD, TUBB4A, GCH1
cation binding (GO:0043169) 1.47CACNA1B, GNAL, GCH1, ATP1A3, HPCA, THAP1, PNKD
ion binding (GO:0043167) 1.367CACNA1B, GNAL, GCH1, ATP1A3, HPCA, THAP1, PNKD
carbohydrate derivative binding (GO:0097367) 2.037ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
nucleotide binding (GO:0000166) 1.967ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
small molecule binding (GO:0036094) 1.897ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
purine ribonucleoside triphosphate binding (GO:0035639) 2.227ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
ribonucleotide binding (GO:0032553) 2.197ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
purine nucleoside binding (GO:0001883) 2.227ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
ribonucleoside binding (GO:0032549) 2.227ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
purine ribonucleotide binding (GO:0032555) 2.27ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
purine nucleotide binding (GO:0017076) 2.197ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
metal ion binding (GO:0046872) 1.417CACNA1B, GNAL, GCH1, ATP1A3, HPCA, THAP1, PNKD
purine ribonucleoside binding (GO:0032550) 2.227ATP1A3, GNAL, TOR1A, CACNA1B, TAF1, TUBB4A, GCH1
nucleoside phosphate binding (GO:1901265) 1.967CACNA1B, GNAL, TOR1A, ATP1A3, TAF1, TUBB4A, GCH1
nucleoside binding (GO:0001882) 2.217CACNA1B, GNAL, TOR1A, ATP1A3, TAF1, TUBB4A, GCH1
hydrolase activity (GO:0016787) 1.96ATP1A3, GNAL, TOR1A, GCH1, TUBB4A, PNKD
identical protein binding (GO:0042802) 2.636GCH1, KCTD17, PRKRA, DRD2, SLC2A1, THAP1
substrate-specific transmembrane transporter activity (GO:0022891) 2.94CACNA1B, ATP1A3, ANO3, SLC2A1
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818) 3.034ATP1A3, TUBB4A, TOR1A, GNAL
substrate-specific transporter activity (GO:0022892) 2.724CACNA1B, ATP1A3, ANO3, SLC2A1
adenyl nucleotide binding (GO:0030554) 2.44CACNA1B, ATP1A3, TOR1A, TAF1
transporter activity (GO:0005215) 2.574CACNA1B, ATP1A3, ANO3, SLC2A1
hydrolase activity, acting on acid anhydrides (GO:0016817) 3.034TOR1A, ATP1A3, TUBB4A, GNAL
nucleoside-triphosphatase activity (GO:0017111) 3.094TOR1A, ATP1A3, TUBB4A, GNAL
pyrophosphatase activity (GO:0016462) 3.044ATP1A3, TUBB4A, TOR1A, GNAL
transmembrane transporter activity (GO:0022857) 2.824CACNA1B, ATP1A3, ANO3, SLC2A1
adenyl ribonucleotide binding (GO:0032559) 2.414ATP1A3, CACNA1B, TOR1A, TAF1
protein dimerization activity (GO:0046983) 2.724ANO3, PRKRA, DRD2, GCH1
ATP binding (GO:0005524) 2.434ATP1A3, CACNA1B, TOR1A, TAF1
guanyl nucleotide binding (GO:0019001) 3.733TUBB4A, GCH1, GNAL
enzyme binding (GO:0019899) 2.273SLC2A1, PRKRA, HPCA
ion transmembrane transporter activity (GO:0015075) 3.043CACNA1B, ATP1A3, ANO3
guanyl ribonucleotide binding (GO:0032561) 3.733TUBB4A, GCH1, GNAL
calcium ion binding (GO:0005509) 3.173CACNA1B, HPCA, GCH1
nucleic acid binding (GO:0003676) 1.443PRKRA, THAP1, TAF1
protein homodimerization activity (GO:0042803) 3.163PRKRA, GCH1, DRD2
molecular function regulator (GO:0098772) 2.513COL6A3, PRKRA, DRD2
GTP binding (GO:0005525) 3.783TUBB4A, GCH1, GNAL
ATPase activity (GO:0016887) 3.652ATP1A3, TOR1A
zinc ion binding (GO:0008270) 2.662THAP1, GCH1
signal transducer activity (GO:0004871) 2.282DRD2, GNAL
DNA binding (GO:0003677) 1.922THAP1, TAF1
sequence-specific DNA binding (GO:0043565) 2.792THAP1, TAF1
transition metal ion binding (GO:0046914) 2.482THAP1, GCH1
transferase activity (GO:0016740) 1.952PRKRA, TAF1
passive transmembrane transporter activity (GO:0022803) 3.62CACNA1B, ANO3
metal ion transmembrane transporter activity (GO:0046873) 3.712CACNA1B, ATP1A3
ion channel activity (GO:0005216) 3.712CACNA1B, ANO3
kinase activity (GO:0016301) 2.932PRKRA, TAF1
enzyme regulator activity (GO:0030234) 2.852COL6A3, PRKRA
cation transmembrane transporter activity (GO:0008324) 3.322CACNA1B, ATP1A3
GTPase activity (GO:0003924) 4.312TUBB4A, GNAL
kinase binding (GO:0019900) 3.322SLC2A1, HPCA
inorganic cation transmembrane transporter activity (GO:0022890) 3.492CACNA1B, ATP1A3
cytoskeletal protein binding (GO:0008092) 3.022HPCA, TOR1A
transferase activity, transferring phosphorus-containing groups (GO:0016772) 2.772PRKRA, TAF1
channel activity (GO:0015267) 3.62CACNA1B, ANO3
gated channel activity (GO:0022836) 3.962CACNA1B, ANO3
receptor binding (GO:0005102) 2.432ATP1A3, DRD2
substrate-specific channel activity (GO:0022838) 3.672CACNA1B, ANO3
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cellular process (GO:0009987) 0.2616CACNA1B, TOR1A, GCH1, KCTD17, PRKRA, ATP1A3, DRD2, SGCE, SLC2A1, THAP1, TAF1, ANO3, HPCA, TUBB4A, COL6A3, PNKD
single-organism process (GO:0044699) 0.4816CACNA1B, TOR1A, GCH1, KCTD17, PRKRA, ATP1A3, DRD2, SGCE, SLC2A1, THAP1, TAF1, ANO3, HPCA, TUBB4A, COL6A3, PNKD
biological regulation (GO:0065007) 0.3915CACNA1B, GNAL, GCH1, KCTD17, PRKRA, ATP1A3, DRD2, TOR1A, SLC2A1, THAP1, TAF1, ANO3, HPCA, COL6A3, PNKD
regulation of biological process (GO:0050789) 0.4514CACNA1B, TOR1A, GCH1, GNAL, KCTD17, PRKRA, ATP1A3, DRD2, SLC2A1, THAP1, TAF1, HPCA, COL6A3, PNKD
single-organism cellular process (GO:0044763) 0.6513ATP1A3, TOR1A, KCTD17, PRKRA, CACNA1B, DRD2, SLC2A1, THAP1, TAF1, ANO3, TUBB4A, COL6A3, PNKD
regulation of cellular process (GO:0050794) 0.513ATP1A3, TOR1A, GCH1, GNAL, KCTD17, PRKRA, DRD2, SLC2A1, THAP1, TAF1, HPCA, COL6A3, PNKD
response to stimulus (GO:0050896) 1.2211CACNA1B, TOR1A, GCH1, PRKRA, PRRT2, ATP1A3, HPCA, SLC2A1, DRD2, ANO3, TAF1
organic substance metabolic process (GO:0071704) 0.6310TOR1A, GCH1, KCTD17, PRKRA, DRD2, SLC2A1, THAP1, TAF1, COL6A3, PNKD
metabolic process (GO:0008152) 0.5810TOR1A, GCH1, KCTD17, PRKRA, DRD2, SLC2A1, THAP1, TAF1, COL6A3, PNKD
multicellular organismal process (GO:0032501) 1.459ATP1A3, GNAL, GCH1, COL6A3, PRRT2, CACNA1B, DRD2, SGCE, PNKD
regulation of metabolic process (GO:0019222) 1.029GNAL, GCH1, COL6A3, PRKRA, HPCA, THAP1, DRD2, TAF1, PNKD
cellular metabolic process (GO:0044237) 0.699TOR1A, GCH1, KCTD17, PRKRA, DRD2, SLC2A1, THAP1, TAF1, PNKD
cellular component organization (GO:0016043) 1.249ANO3, GCH1, KCTD17, DRD2, TOR1A, SLC2A1, TAF1, SGCE, COL6A3
regulation of biological quality (GO:0065008) 1.689CACNA1B, TOR1A, GCH1, KCTD17, ATP1A3, DRD2, SLC2A1, ANO3, PNKD
cellular component organization or biogenesis (GO:0071840) 1.229ANO3, GCH1, KCTD17, DRD2, TOR1A, SLC2A1, TAF1, SGCE, COL6A3
positive regulation of biological process (GO:0048518) 1.28GNAL, TOR1A, KCTD17, PRKRA, DRD2, TAF1, HPCA, GCH1
regulation of cellular metabolic process (GO:0031323) 1.078GNAL, GCH1, COL6A3, HPCA, THAP1, DRD2, TAF1, PNKD
primary metabolic process (GO:0044238) 0.697TOR1A, KCTD17, PRKRA, DRD2, SLC2A1, THAP1, TAF1
regulation of primary metabolic process (GO:0080090) 1.087GNAL, COL6A3, HPCA, THAP1, DRD2, TAF1, PNKD
macromolecule metabolic process (GO:0043170) 0.837TOR1A, KCTD17, PRKRA, DRD2, THAP1, TAF1, COL6A3
response to stress (GO:0006950) 1.87CACNA1B, GCH1, TOR1A, PRKRA, DRD2, SLC2A1, TAF1
regulation of signaling (GO:0023051) 1.727ATP1A3, TOR1A, PRKRA, DRD2, SLC2A1, TAF1, PNKD
positive regulation of cellular process (GO:0048522) 1.37GNAL, TOR1A, KCTD17, PRKRA, HPCA, DRD2, TAF1
system process (GO:0003008) 2.37ATP1A3, GNAL, GCH1, PRRT2, DRD2, SGCE, PNKD
establishment of localization (GO:0051234) 1.486CACNA1B, TOR1A, ATP1A3, DRD2, SLC2A1, ANO3
regulation of localization (GO:0032879) 1.946CACNA1B, TOR1A, HPCA, SLC2A1, DRD2, PNKD
cellular macromolecule metabolic process (GO:0044260) 0.936TOR1A, KCTD17, PRKRA, DRD2, THAP1, TAF1
regulation of transport (GO:0051049) 2.246CACNA1B, TOR1A, HPCA, SLC2A1, DRD2, PNKD
regulation of catalytic activity (GO:0050790) 1.976GCH1, GNAL, COL6A3, PRKRA, HPCA, DRD2
single-organism transport (GO:0044765) 2.186ATP1A3, TOR1A, CACNA1B, DRD2, SLC2A1, ANO3
cellular component assembly (GO:0022607) 2.146GCH1, TOR1A, KCTD17, DRD2, SLC2A1, TAF1
regulation of nitrogen compound metabolic process (GO:0051171) 1.366GNAL, HPCA, THAP1, DRD2, TAF1, PNKD
transport (GO:0006810) 1.516CACNA1B, TOR1A, ATP1A3, DRD2, SLC2A1, ANO3
neurological system process (GO:0050877) 2.646ATP1A3, GCH1, GNAL, PRRT2, DRD2, PNKD
regulation of molecular function (GO:0065009) 1.786GCH1, GNAL, COL6A3, PRKRA, HPCA, DRD2
regulation of cell communication (GO:0010646) 1.736TOR1A, PRKRA, DRD2, SLC2A1, TAF1, PNKD
localization (GO:0051179) 1.46ATP1A3, TOR1A, CACNA1B, DRD2, SLC2A1, ANO3
single-organism localization (GO:1902578) 2.096ATP1A3, TOR1A, CACNA1B, DRD2, SLC2A1, ANO3
positive regulation of cellular component organization (GO:0051130) 2.685KCTD17, DRD2, TOR1A, HPCA, TAF1
positive regulation of metabolic process (GO:0009893) 1.745GCH1, DRD2, HPCA, GNAL, TAF1
macromolecular complex subunit organization (GO:0043933) 2.145SLC2A1, KCTD17, TOR1A, GCH1, TAF1
regulation of cellular biosynthetic process (GO:0031326) 1.385HPCA, TAF1, THAP1, DRD2, GNAL
regulation of cellular component organization (GO:0051128) 2.015HPCA, KCTD17, DRD2, TOR1A, TAF1
nitrogen compound metabolic process (GO:0006807) 1.135PRKRA, TAF1, THAP1, DRD2, GCH1
positive regulation of catalytic activity (GO:0043085) 2.45HPCA, GCH1, PRKRA, DRD2, GNAL
cellular response to stimulus (GO:0051716) 1.975ATP1A3, PRKRA, TAF1, HPCA, SLC2A1
macromolecular complex assembly (GO:0065003) 2.555TAF1, KCTD17, GCH1, TOR1A, SLC2A1
regulation of macromolecule metabolic process (GO:0060255) 1.085PRKRA, COL6A3, THAP1, TAF1, DRD2
organic cyclic compound metabolic process (GO:1901360) 1.265PRKRA, TAF1, THAP1, DRD2, GCH1
positive regulation of molecular function (GO:0044093) 2.235HPCA, GCH1, PRKRA, DRD2, GNAL
negative regulation of biological process (GO:0048519) 1.335HPCA, COL6A3, PRKRA, PNKD, DRD2
developmental process (GO:0032502) 1.365SGCE, COL6A3, PRKRA, DRD2, HPCA
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.435TAF1, DRD2, THAP1, HPCA, GNAL
regulation of biosynthetic process (GO:0009889) 1.375HPCA, TAF1, THAP1, DRD2, GNAL
ion transport (GO:0006811) 2.665ANO3, CACNA1B, ATP1A3, DRD2, SLC2A1
cellular aromatic compound metabolic process (GO:0006725) 1.35PRKRA, GCH1, THAP1, TAF1, DRD2
single-organism developmental process (GO:0044767) 1.495SGCE, COL6A3, PRKRA, DRD2, HPCA
response to chemical (GO:0042221) 1.985GCH1, ATP1A3, PRKRA, DRD2, HPCA
transmembrane transport (GO:0055085) 2.725ANO3, CACNA1B, ATP1A3, DRD2, SLC2A1
response to abiotic stimulus (GO:0009628) 2.85ANO3, ATP1A3, DRD2, HPCA, SLC2A1
single-multicellular organism process (GO:0044707) 1.785CACNA1B, ATP1A3, DRD2, COL6A3, GCH1
response to external stimulus (GO:0009605) 2.555ANO3, SLC2A1, PRKRA, DRD2, GCH1
negative regulation of cellular process (GO:0048523) 1.415HPCA, COL6A3, PRKRA, PNKD, DRD2
negative regulation of metabolic process (GO:0009892) 1.934COL6A3, PRKRA, HPCA, DRD2
regulation of cellular localization (GO:0060341) 3.034TOR1A, DRD2, PNKD, HPCA
positive regulation of biosynthetic process (GO:0009891) 2.294TAF1, DRD2, HPCA, GNAL
positive regulation of cellular metabolic process (GO:0031325) 1.814HPCA, TAF1, DRD2, GNAL
regulation of response to stimulus (GO:0048583) 1.544TAF1, PRKRA, DRD2, GCH1
cellular biosynthetic process (GO:0044249) 1.374SLC2A1, THAP1, TAF1, GCH1
cellular nitrogen compound metabolic process (GO:0034641) 1.224PRKRA, THAP1, GCH1, TAF1
signal transduction (GO:0007165) 1.284ATP1A3, DRD2, HPCA, GNAL
neuromuscular process (GO:0050905) 5.274DRD2, PRRT2, PNKD, GCH1
regulation of protein localization (GO:0032880) 2.884HPCA, SLC2A1, DRD2, TOR1A
organic substance biosynthetic process (GO:1901576) 1.344SLC2A1, THAP1, TAF1, GCH1
single-organism metabolic process (GO:0044710) 1.634COL6A3, DRD2, PNKD, SLC2A1
protein complex subunit organization (GO:0071822) 2.64KCTD17, TOR1A, GCH1, SLC2A1
positive regulation of cellular biosynthetic process (GO:0031328) 2.34HPCA, TAF1, DRD2, GNAL
organic substance transport (GO:0071702) 2.154ANO3, SLC2A1, TOR1A, DRD2
regulation of gene expression (GO:0010468) 1.374PRKRA, THAP1, TAF1, DRD2
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 2.354HPCA, TAF1, DRD2, GNAL
protein complex assembly (GO:0006461) 2.784KCTD17, TOR1A, GCH1, SLC2A1
ion transmembrane transport (GO:0034220) 3.084ANO3, ATP1A3, CACNA1B, DRD2
biosynthetic process (GO:0009058) 1.324SLC2A1, THAP1, TAF1, GCH1
positive regulation of nitrogen compound metabolic process (GO:0051173) 2.294HPCA, TAF1, DRD2, GNAL
cell communication (GO:0007154) 3.044CACNA1B, ATP1A3, DRD2, SLC2A1
catabolic process (GO:0009056) 2.384KCTD17, COL6A3, PNKD, TOR1A
response to organic substance (GO:0010033) 2.24HPCA, ATP1A3, DRD2, GCH1
heterocycle metabolic process (GO:0046483) 1.314PRKRA, THAP1, GCH1, TAF1
response to oxygen-containing compound (GO:1901700) 2.574ATP1A3, DRD2, HPCA, GCH1
protein metabolic process (GO:0019538) 1.454KCTD17, PRKRA, TAF1, TOR1A
anatomical structure development (GO:0048856) 1.584HPCA, COL6A3, SGCE, DRD2
inorganic ion transmembrane transport (GO:0098660) 3.384ANO3, ATP1A3, CACNA1B, DRD2
phosphate-containing compound metabolic process (GO:0006796) 2.164TAF1, PRKRA, DRD2, GCH1
phosphorus metabolic process (GO:0006793) 2.154TAF1, PRKRA, DRD2, GCH1
regulation of neurotransmitter levels (GO:0001505) 4.774CACNA1B, DRD2, PNKD, TOR1A
regulation of cyclic nucleotide metabolic process (GO:0030799) 4.693HPCA, DRD2, GNAL
regulation of phosphate metabolic process (GO:0019220) 2.353HPCA, DRD2, GNAL
regulation of secretion (GO:0051046) 3.23SLC2A1, DRD2, PNKD
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.463THAP1, TAF1, DRD2
behavior (GO:0007610) 3.473ATP1A3, CACNA1B, DRD2
membrane organization (GO:0061024) 3.043ANO3, TOR1A, SGCE
muscle system process (GO:0003012) 4.183ATP1A3, DRD2, SGCE
inorganic ion homeostasis (GO:0098771) 3.433ATP1A3, KCTD17, DRD2
organic cyclic compound biosynthetic process (GO:1901362) 1.663THAP1, TAF1, GCH1
regulation of signal transduction (GO:0009966) 1.843PRKRA, TAF1, DRD2
animal organ development (GO:0048513) 2.533COL6A3, SGCE, HPCA
negative regulation of molecular function (GO:0044092) 2.743COL6A3, HPCA, DRD2
cellular homeostasis (GO:0019725) 3.233KCTD17, ATP1A3, DRD2
positive regulation of transport (GO:0051050) 2.93DRD2, TOR1A, HPCA
regulation of RNA biosynthetic process (GO:2001141) 1.553THAP1, TAF1, DRD2
regulation of cyclase activity (GO:0031279) 5.323DRD2, HPCA, GNAL
regulation of synaptic transmission, dopaminergic (GO:0032225) 6.93DRD2, PNKD, TOR1A
response to biotic stimulus (GO:0009607) 3.093PRRT2, PRKRA, GCH1
anion transport (GO:0006820) 3.713SLC2A1, ANO3, DRD2
regulation of purine nucleotide biosynthetic process (GO:1900371) 4.83DRD2, HPCA, GNAL
cellular response to stress (GO:0033554) 2.513SLC2A1, PRKRA, TAF1
aromatic compound biosynthetic process (GO:0019438) 1.73THAP1, TAF1, GCH1
chemical homeostasis (GO:0048878) 2.973KCTD17, ATP1A3, DRD2
regulation of neurotransmitter transport (GO:0051588) 5.553TOR1A, PNKD, DRD2
regulation of protein transport (GO:0051223) 3.123SLC2A1, HPCA, DRD2
cellular protein metabolic process (GO:0044267) 1.633PRKRA, TAF1, TOR1A
organic substance catabolic process (GO:1901575) 2.453KCTD17, TOR1A, PNKD
inorganic cation transmembrane transport (GO:0098662) 3.553CACNA1B, ATP1A3, DRD2
heterocycle biosynthetic process (GO:0018130) 1.73THAP1, TAF1, GCH1
locomotory behavior (GO:0007626) 4.533CACNA1B, ATP1A3, DRD2
regulation of establishment of protein localization (GO:0070201) 3.023SLC2A1, DRD2, HPCA
cation transport (GO:0006812) 3.113ATP1A3, CACNA1B, DRD2
regulation of heart contraction (GO:0008016) 4.353ATP1A3, CACNA1B, DRD2
macromolecule modification (GO:0043412) 1.733PRKRA, TAF1, TOR1A
protein modification process (GO:0036211) 1.793PRKRA, TAF1, TOR1A
regulation of blood circulation (GO:1903522) 4.053ATP1A3, CACNA1B, DRD2
regulation of multicellular organismal process (GO:0051239) 1.873ATP1A3, CACNA1B, DRD2
regulation of intracellular signal transduction (GO:1902531) 2.313PRKRA, TAF1, DRD2
regulation of hydrolase activity (GO:0051336) 2.533COL6A3, DRD2, HPCA
cellular nitrogen compound biosynthetic process (GO:0044271) 1.593THAP1, TAF1, GCH1
regulation of lyase activity (GO:0051339) 5.33DRD2, HPCA, GNAL
regulation of transcription, DNA-templated (GO:0006355) 1.563THAP1, TAF1, DRD2
regulation of macromolecule biosynthetic process (GO:0010556) 1.433THAP1, TAF1, DRD2
positive regulation of phosphorus metabolic process (GO:0010562) 2.783HPCA, DRD2, GNAL
ion homeostasis (GO:0050801) 3.423ATP1A3, KCTD17, DRD2
metal ion homeostasis (GO:0055065) 3.613KCTD17, ATP1A3, DRD2
modulation of synaptic transmission (GO:0050804) 4.093DRD2, PNKD, TOR1A
cellular catabolic process (GO:0044248) 2.623KCTD17, TOR1A, PNKD
regulation of secretion by cell (GO:1903530) 3.283SLC2A1, DRD2, PNKD
cellular response to chemical stimulus (GO:0070887) 2.573ATP1A3, PRKRA, HPCA
negative regulation of catalytic activity (GO:0043086) 3.03COL6A3, DRD2, HPCA
response to organic cyclic compound (GO:0014070) 3.073ATP1A3, DRD2, HPCA
response to endogenous stimulus (GO:0009719) 2.793ATP1A3, DRD2, HPCA
nucleobase-containing compound metabolic process (GO:0006139) 1.353PRKRA, THAP1, TAF1
regulation of system process (GO:0044057) 3.533ATP1A3, CACNA1B, DRD2
neuromuscular process controlling posture (GO:0050884) 7.243PRRT2, GCH1, PNKD
regulation of cAMP biosynthetic process (GO:0030817) 5.013DRD2, HPCA, GNAL
regulation of cAMP metabolic process (GO:0030814) 4.883DRD2, HPCA, GNAL
regulation of protein metabolic process (GO:0051246) 1.933COL6A3, TAF1, DRD2
biological adhesion (GO:0022610) 2.813COL6A3, TOR1A, SGCE
RNA metabolic process (GO:0016070) 1.593PRKRA, THAP1, TAF1
cellular metal ion homeostasis (GO:0006875) 3.753ATP1A3, KCTD17, DRD2
regulation of nucleic acid-templated transcription (GO:1903506) 1.553THAP1, TAF1, DRD2
metal ion transport (GO:0030001) 3.363ATP1A3, CACNA1B, DRD2
cellular cation homeostasis (GO:0030003) 3.63ATP1A3, KCTD17, DRD2
cation homeostasis (GO:0055080) 3.463ATP1A3, KCTD17, DRD2
cellular chemical homeostasis (GO:0055082) 3.43ATP1A3, KCTD17, DRD2
protein oligomerization (GO:0051259) 3.713KCTD17, TOR1A, GCH1
nucleic acid metabolic process (GO:0090304) 1.463PRKRA, THAP1, TAF1
regulation of cellular protein metabolic process (GO:0032268) 1.993COL6A3, TAF1, DRD2
regulation of nucleotide biosynthetic process (GO:0030808) 4.793HPCA, DRD2, GNAL
regulation of RNA metabolic process (GO:0051252) 1.523THAP1, TAF1, DRD2
regulation of cyclic nucleotide biosynthetic process (GO:0030802) 4.853DRD2, HPCA, GNAL
cell projection organization (GO:0030030) 3.143KCTD17, DRD2, TOR1A
negative regulation of cellular metabolic process (GO:0031324) 2.013COL6A3, HPCA, DRD2
homeostatic process (GO:0042592) 2.613KCTD17, ATP1A3, DRD2
regulation of blood pressure (GO:0008217) 4.723CACNA1B, DRD2, GCH1
regulation of adenylate cyclase activity (GO:0045761) 5.513HPCA, DRD2, GNAL
protein homooligomerization (GO:0051260) 4.213KCTD17, GCH1, TOR1A
positive regulation of phosphate metabolic process (GO:0045937) 2.783DRD2, HPCA, GNAL
cellular protein modification process (GO:0006464) 1.793PRKRA, TAF1, TOR1A
regulation of phosphorus metabolic process (GO:0051174) 2.353HPCA, DRD2, GNAL
cellular ion homeostasis (GO:0006873) 3.573KCTD17, ATP1A3, DRD2
establishment of localization in cell (GO:0051649) 2.473CACNA1B, TOR1A, DRD2
cell adhesion (GO:0007155) 2.823COL6A3, TOR1A, SGCE
regulation of purine nucleotide metabolic process (GO:1900542) 4.413HPCA, DRD2, GNAL
regulation of nucleotide metabolic process (GO:0006140) 4.383DRD2, HPCA, GNAL
cation transmembrane transport (GO:0098655) 3.433CACNA1B, ATP1A3, DRD2
regulation of peptide transport (GO:0090087) 4.372SLC2A1, DRD2
protein localization (GO:0008104) 2.362DRD2, TOR1A
negative regulation of secretion (GO:0051048) 4.442DRD2, PNKD
positive regulation of response to stimulus (GO:0048584) 2.182PRKRA, DRD2
learning (GO:0007612) 4.852ATP1A3, DRD2
memory (GO:0007613) 5.132ATP1A3, DRD2
learning or memory (GO:0007611) 4.332ATP1A3, DRD2
small molecule metabolic process (GO:0044281) 2.382SLC2A1, PNKD
cell surface receptor signaling pathway (GO:0007166) 2.092ATP1A3, DRD2
regulation of ion transmembrane transport (GO:0034765) 3.772CACNA1B, DRD2
positive regulation of receptor-mediated endocytosis (GO:0048260) 5.842TOR1A, DRD2
negative regulation of nucleotide metabolic process (GO:0045980) 5.62DRD2, HPCA
positive regulation of nucleotide metabolic process (GO:0045981) 4.852HPCA, GNAL
regulation of transmembrane transport (GO:0034762) 3.742CACNA1B, DRD2
response to pain (GO:0048265) 6.782CACNA1B, GCH1
single-organism catabolic process (GO:0044712) 3.212COL6A3, PNKD
regulation of insulin secretion (GO:0050796) 4.572SLC2A1, DRD2
negative regulation of macromolecule metabolic process (GO:0010605) 2.012COL6A3, PRKRA
positive regulation of macromolecule metabolic process (GO:0010604) 1.812TAF1, DRD2
response to external biotic stimulus (GO:0043207) 3.132PRKRA, GCH1
dopamine receptor signaling pathway (GO:0007212) 6.262DRD2, GNAL
positive regulation of signal transduction (GO:0009967) 2.52PRKRA, DRD2
interspecies interaction between organisms (GO:0044419) 3.082PRKRA, TAF1
phosphorylation (GO:0016310) 2.632PRKRA, TAF1
regulation of amine transport (GO:0051952) 5.622TOR1A, DRD2
macromolecule localization (GO:0033036) 2.342TOR1A, DRD2
regulation of cell proliferation (GO:0042127) 2.412PRKRA, DRD2
sensory perception of smell (GO:0007608) 3.612DRD2, GNAL
negative regulation of transport (GO:0051051) 3.62DRD2, PNKD
sensory perception of chemical stimulus (GO:0007606) 3.492DRD2, GNAL
organic anion transport (GO:0015711) 4.072SLC2A1, DRD2
regulation of peptide hormone secretion (GO:0090276) 4.412SLC2A1, DRD2
regulation of proteolysis (GO:0030162) 3.22COL6A3, TAF1
protein catabolic process (GO:0030163) 3.932KCTD17, TOR1A
signaling (GO:0023052) 3.252CACNA1B, DRD2
oxoacid metabolic process (GO:0043436) 3.122SLC2A1, PNKD
negative regulation of nucleotide biosynthetic process (GO:0030809) 6.072DRD2, HPCA
multi-organism process (GO:0051704) 2.652PRKRA, TAF1
single organism signaling (GO:0044700) 3.252CACNA1B, DRD2
organonitrogen compound metabolic process (GO:1901564) 2.322DRD2, GCH1
vesicle-mediated transport (GO:0016192) 2.722TOR1A, DRD2
cell motility (GO:0048870) 3.022TOR1A, DRD2
single-organism behavior (GO:0044708) 3.792ATP1A3, DRD2
response to organonitrogen compound (GO:0010243) 3.22DRD2, HPCA
negative regulation of purine nucleotide biosynthetic process (GO:1900372) 6.072HPCA, DRD2
positive regulation of purine nucleotide biosynthetic process (GO:1900373) 5.092HPCA, GNAL
anterograde trans-synaptic signaling (GO:0098916) 3.982CACNA1B, DRD2
multicellular organismal response to stress (GO:0033555) 5.672CACNA1B, GCH1
organophosphate metabolic process (GO:0019637) 3.042DRD2, GCH1
negative regulation of secretion by cell (GO:1903531) 4.552DRD2, PNKD
calcium ion homeostasis (GO:0055074) 3.972KCTD17, DRD2
regulation of membrane potential (GO:0042391) 3.892CACNA1B, ATP1A3
visual behavior (GO:0007632) 5.822ATP1A3, DRD2
negative regulation of biosynthetic process (GO:0009890) 2.472HPCA, DRD2
positive regulation of cyclic nucleotide metabolic process (GO:0030801) 5.052HPCA, GNAL
movement of cell or subcellular component (GO:0006928) 2.612DRD2, TOR1A
regulation of neurotransmitter uptake (GO:0051580) 7.022DRD2, TOR1A
positive regulation of gene expression (GO:0010628) 2.352TAF1, DRD2
regulation of dopamine uptake involved in synaptic transmission (GO:0051584) 7.652TOR1A, DRD2
intracellular signal transduction (GO:0035556) 2.392HPCA, DRD2
nucleic acid-templated transcription (GO:0097659) 1.912THAP1, TAF1
cellular macromolecule catabolic process (GO:0044265) 3.192KCTD17, TOR1A
regulation of protein secretion (GO:0050708) 3.772SLC2A1, DRD2
positive regulation of lyase activity (GO:0051349) 5.652HPCA, GNAL
adenylate cyclase-modulating G-protein coupled receptor signaling pathway (GO:0007188) 4.782DRD2, GNAL
adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189) 5.522DRD2, GNAL
positive regulation of RNA metabolic process (GO:0051254) 2.512TAF1, DRD2
cell migration (GO:0016477) 3.122TOR1A, DRD2
G-protein coupled receptor signaling pathway (GO:0007186) 2.642DRD2, GNAL
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187) 4.62DRD2, GNAL
regulation of developmental process (GO:0050793) 2.12KCTD17, DRD2
catecholamine metabolic process (GO:0006584) 6.022DRD2, GCH1
calcium ion transport (GO:0006816) 4.332CACNA1B, DRD2
associative learning (GO:0008306) 5.442ATP1A3, DRD2
single-organism membrane organization (GO:0044802) 3.192ANO3, TOR1A
regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) 7.652TOR1A, DRD2
nucleobase-containing compound biosynthetic process (GO:0034654) 1.722THAP1, TAF1
positive regulation of intracellular signal transduction (GO:1902533) 2.952PRKRA, DRD2
regulation of receptor-mediated endocytosis (GO:0048259) 5.352DRD2, TOR1A
macromolecule biosynthetic process (GO:0009059) 1.612THAP1, TAF1
proteolysis involved in cellular protein catabolic process (GO:0051603) 3.592KCTD17, TOR1A
secretion (GO:0046903) 3.382CACNA1B, DRD2
regulation of response to stress (GO:0080134) 2.532DRD2, GCH1
proteasomal protein catabolic process (GO:0010498) 4.122KCTD17, TOR1A
sensory perception (GO:0007600) 2.932DRD2, GNAL
positive regulation of macromolecule biosynthetic process (GO:0010557) 2.392TAF1, DRD2
ubiquitin-dependent protein catabolic process (GO:0006511) 3.722KCTD17, TOR1A
transcription, DNA-templated (GO:0006351) 1.912THAP1, TAF1
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) 5.482DRD2, GNAL
synaptic signaling (GO:0099536) 3.982CACNA1B, DRD2
trans-synaptic signaling (GO:0099537) 3.982CACNA1B, DRD2
catechol-containing compound metabolic process (GO:0009712) 6.022DRD2, GCH1
RNA biosynthetic process (GO:0032774) 1.842THAP1, TAF1
lipid transport (GO:0006869) 4.242ANO3, DRD2
response to radiation (GO:0009314) 3.692ATP1A3, DRD2
negative regulation of synaptic transmission (GO:0050805) 5.672DRD2, PNKD
regulation of cellular protein localization (GO:1903827) 3.432TOR1A, HPCA
negative regulation of signaling (GO:0023057) 2.652DRD2, PNKD
response to light stimulus (GO:0009416) 4.082ATP1A3, DRD2
negative regulation of cell communication (GO:0010648) 2.662DRD2, PNKD
cellular macromolecule biosynthetic process (GO:0034645) 1.662THAP1, TAF1
muscle structure development (GO:0061061) 4.962COL6A3, SGCE
positive regulation of cell communication (GO:0010647) 2.412PRKRA, DRD2
positive regulation of establishment of protein localization (GO:1904951) 3.492HPCA, DRD2
visual learning (GO:0008542) 5.922ATP1A3, DRD2
cell cycle (GO:0007049) 3.142THAP1, TAF1
divalent inorganic cation homeostasis (GO:0072507) 3.92KCTD17, DRD2
cellular divalent inorganic cation homeostasis (GO:0072503) 3.962KCTD17, DRD2
positive regulation of cAMP biosynthetic process (GO:0030819) 5.352HPCA, GNAL
positive regulation of cAMP metabolic process (GO:0030816) 5.252HPCA, GNAL
proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 4.162KCTD17, TOR1A
negative regulation of phosphorus metabolic process (GO:0010563) 3.452HPCA, DRD2
positive regulation of protein metabolic process (GO:0051247) 2.432TAF1, DRD2
positive regulation of nucleotide biosynthetic process (GO:0030810) 5.092HPCA, GNAL
macromolecule catabolic process (GO:0009057) 3.02KCTD17, TOR1A
muscle organ development (GO:0007517) 4.982COL6A3, SGCE
positive regulation of cellular protein metabolic process (GO:0032270) 2.492TAF1, DRD2
proteolysis (GO:0006508) 2.732KCTD17, TOR1A
positive regulation of nucleic acid-templated transcription (GO:1903508) 2.562TAF1, DRD2
negative regulation of cell proliferation (GO:0008285) 3.262PRKRA, DRD2
cognition (GO:0050890) 4.22ATP1A3, DRD2
cellular calcium ion homeostasis (GO:0006874) 4.012KCTD17, DRD2
modification-dependent protein catabolic process (GO:0019941) 3.712KCTD17, TOR1A
regulation of vesicle-mediated transport (GO:0060627) 3.632TOR1A, DRD2
dopamine metabolic process (GO:0042417) 6.512DRD2, GCH1
regulation of hormone secretion (GO:0046883) 4.182SLC2A1, DRD2
positive regulation of transcription, DNA-templated (GO:0045893) 2.562TAF1, DRD2
phenol-containing compound metabolic process (GO:0018958) 5.332DRD2, GCH1
response to oxidative stress (GO:0006979) 3.92PRKRA, TOR1A
negative regulation of lyase activity (GO:0051350) 6.432HPCA, DRD2
divalent metal ion transport (GO:0070838) 4.152CACNA1B, DRD2
organic acid metabolic process (GO:0006082) 3.012SLC2A1, PNKD
positive regulation of developmental process (GO:0051094) 2.772KCTD17, DRD2
positive regulation of cyclic nucleotide biosynthetic process (GO:0030804) 5.142HPCA, GNAL
response to drug (GO:0042493) 3.712ATP1A3, DRD2
negative regulation of cyclic nucleotide metabolic process (GO:0030800) 5.992DRD2, HPCA
negative regulation of cyclic nucleotide biosynthetic process (GO:0030803) 6.122DRD2, HPCA
positive regulation of RNA biosynthetic process (GO:1902680) 2.542TAF1, DRD2
positive regulation of transcription from RNA polymerase II promoter (GO:0045944) 2.812TAF1, DRD2
negative regulation of blood pressure (GO:0045776) 5.992DRD2, GCH1
response to nitrogen compound (GO:1901698) 3.122DRD2, HPCA
negative regulation of cyclase activity (GO:0031280) 6.512HPCA, DRD2
positive regulation of cyclase activity (GO:0031281) 5.652HPCA, GNAL
negative regulation of cellular biosynthetic process (GO:0031327) 2.492HPCA, DRD2
divalent inorganic cation transport (GO:0072511) 4.132CACNA1B, DRD2
calcium ion transmembrane transport (GO:0070588) 4.672CACNA1B, DRD2
carboxylic acid metabolic process (GO:0019752) 3.122SLC2A1, PNKD
modification-dependent macromolecule catabolic process (GO:0043632) 3.692KCTD17, TOR1A
positive regulation of protein transport (GO:0051222) 3.612DRD2, HPCA
regulation of ion transport (GO:0043269) 3.42CACNA1B, DRD2
muscle contraction (GO:0006936) 4.372ATP1A3, DRD2
response to lipid (GO:0033993) 3.112ATP1A3, GCH1
positive regulation of adenylate cyclase activity (GO:0045762) 5.92HPCA, GNAL
regulation of transcription from RNA polymerase II promoter (GO:0006357) 2.242TAF1, DRD2
protein phosphorylation (GO:0006468) 2.892PRKRA, TAF1
negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 2.552HPCA, DRD2
negative regulation of phosphate metabolic process (GO:0045936) 3.452HPCA, DRD2
regulation of hormone levels (GO:0010817) 3.562SLC2A1, DRD2
regulation of metal ion transport (GO:0010959) 3.942CACNA1B, DRD2
multi-organism cellular process (GO:0044764) 3.142PRKRA, TAF1
negative regulation of nitrogen compound metabolic process (GO:0051172) 2.472HPCA, DRD2
chemical synaptic transmission (GO:0007268) 3.982CACNA1B, DRD2
cell-cell signaling (GO:0007267) 3.352CACNA1B, DRD2
regulation of endocytosis (GO:0030100) 4.422DRD2, TOR1A
adult locomotory behavior (GO:0008344) 5.32ATP1A3, DRD2
positive regulation of signaling (GO:0023056) 2.412PRKRA, DRD2
locomotion (GO:0040011) 2.912DRD2, TOR1A
adult behavior (GO:0030534) 4.792ATP1A3, DRD2
negative regulation of purine nucleotide metabolic process (GO:1900543) 5.622DRD2, HPCA
positive regulation of purine nucleotide metabolic process (GO:1900544) 4.852HPCA, GNAL
regulation of cell cycle (GO:0051726) 2.932THAP1, DRD2
regulation of peptide secretion (GO:0002791) 4.382SLC2A1, DRD2
regulation of calcium ion transport (GO:0051924) 4.382CACNA1B, DRD2
regulation of cellular component biogenesis (GO:0044087) 3.082KCTD17, TAF1
anatomical structure morphogenesis (GO:0009653) 2.532PRKRA, DRD2
viral process (GO:0016032) 3.152PRKRA, TAF1
symbiosis, encompassing mutualism through parasitism (GO:0044403) 3.152PRKRA, TAF1
positive regulation of endocytosis (GO:0045807) 4.982DRD2, TOR1A
organic hydroxy compound metabolic process (GO:1901615) 3.842DRD2, GCH1
positive regulation of cellular component biogenesis (GO:0044089) 3.712KCTD17, TAF1

NET-GE enrichment

Term New enriched termICP valueGenes
neurological system process (GO:0050877) -2.640.048ATP1A3, GNAL, GCH1, PRRT2, DRD2, SLC2A1, TAF1, SGCE, TUBB4A, PNKD
regulation of synaptic transmission, dopaminergic (GO:0032225) -6.90.0TOR1A, PNKD, DRD2
regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) -7.650.03DRD2, TOR1A
regulation of dopamine uptake involved in synaptic transmission (GO:0051584) -7.650.03DRD2, TOR1A
neuromuscular process controlling posture (GO:0050884) -7.240.005PRRT2, PNKD, GCH1
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cell part (GO:0044464) 0.1118ATP1A3, TOR1A, GCH1, PRKRA, GNAL, KCTD17, PRRT2, CACNA1B, DRD2, SGCE, SLC2A1, THAP1, TAF1, ANO3, HPCA, TUBB4A, COL6A3, PNKD
intracellular part (GO:0044424) 0.2814ATP1A3, TOR1A, GCH1, KCTD17, PRKRA, TAF1, SLC2A1, THAP1, DRD2, SGCE, HPCA, TUBB4A, COL6A3, PNKD
membrane (GO:0016020) 0.6814CACNA1B, TOR1A, GCH1, GNAL, COL6A3, PRRT2, ATP1A3, HPCA, SGCE, SLC2A1, PRKRA, DRD2, ANO3, PNKD
membrane-bounded organelle (GO:0043227) 0.4713ATP1A3, GNAL, GCH1, KCTD17, DRD2, TOR1A, SLC2A1, THAP1, TAF1, SGCE, TUBB4A, COL6A3, PNKD
organelle (GO:0043226) 0.413ATP1A3, GNAL, GCH1, KCTD17, DRD2, TOR1A, SLC2A1, THAP1, TAF1, SGCE, TUBB4A, COL6A3, PNKD
cytoplasmic part (GO:0044444) 0.8212ATP1A3, TOR1A, GCH1, KCTD17, PRKRA, DRD2, SLC2A1, HPCA, SGCE, TUBB4A, COL6A3, PNKD
intracellular organelle (GO:0043229) 0.5111ATP1A3, TOR1A, GCH1, KCTD17, DRD2, SLC2A1, THAP1, TAF1, SGCE, TUBB4A, PNKD
intracellular membrane-bounded organelle (GO:0043231) 0.611ATP1A3, TOR1A, GCH1, KCTD17, DRD2, SLC2A1, THAP1, TAF1, SGCE, TUBB4A, PNKD
cytoplasm (GO:0005737) 1.0110ATP1A3, TOR1A, GCH1, KCTD17, PRKRA, HPCA, SLC2A1, SGCE, TUBB4A, PNKD
intracellular organelle part (GO:0044446) 0.819TOR1A, GCH1, COL6A3, PRKRA, DRD2, SLC2A1, THAP1, TAF1, TUBB4A
membrane part (GO:0044425) 0.959ATP1A3, SGCE, TOR1A, PRRT2, CACNA1B, DRD2, SLC2A1, HPCA, ANO3
organelle part (GO:0044422) 0.799TOR1A, GCH1, COL6A3, PRKRA, DRD2, SLC2A1, THAP1, TAF1, TUBB4A
plasma membrane (GO:0005886) 1.399ATP1A3, SGCE, GNAL, COL6A3, PRRT2, CACNA1B, DRD2, SLC2A1, ANO3
nucleus (GO:0005634) 1.078ATP1A3, TOR1A, GCH1, TAF1, SLC2A1, THAP1, TUBB4A, PNKD
vesicle (GO:0031982) 1.648ATP1A3, GCH1, GNAL, COL6A3, DRD2, TOR1A, SLC2A1, TUBB4A
protein complex (GO:0043234) 1.517CACNA1B, GCH1, KCTD17, ATP1A3, TAF1, SGCE, COL6A3
macromolecular complex (GO:0032991) 1.357CACNA1B, GCH1, KCTD17, ATP1A3, TAF1, SGCE, COL6A3
integral component of membrane (GO:0016021) 1.147ATP1A3, SGCE, PRRT2, CACNA1B, DRD2, SLC2A1, ANO3
neuron part (GO:0097458) 2.647CACNA1B, TOR1A, ATP1A3, HPCA, DRD2, SGCE, TUBB4A
cell projection (GO:0042995) 2.477ATP1A3, TOR1A, CACNA1B, HPCA, DRD2, SGCE, TUBB4A
intrinsic component of membrane (GO:0031224) 1.137ATP1A3, SGCE, PRRT2, CACNA1B, DRD2, SLC2A1, ANO3
extracellular organelle (GO:0043230) 1.896ATP1A3, GNAL, TOR1A, COL6A3, SLC2A1, TUBB4A
intracellular non-membrane-bounded organelle (GO:0043232) 1.766TOR1A, DRD2, SLC2A1, THAP1, SGCE, TUBB4A
cytosol (GO:0005829) 1.686GCH1, TOR1A, PRKRA, DRD2, SLC2A1, TUBB4A
cell projection part (GO:0044463) 2.976ATP1A3, TOR1A, HPCA, DRD2, SGCE, TUBB4A
membrane-bounded vesicle (GO:0031988) 1.716GNAL, TOR1A, COL6A3, DRD2, SLC2A1, TUBB4A
non-membrane-bounded organelle (GO:0043228) 1.766TOR1A, DRD2, SLC2A1, THAP1, SGCE, TUBB4A
neuron projection (GO:0043005) 3.126ATP1A3, TOR1A, CACNA1B, HPCA, DRD2, SGCE
extracellular vesicle (GO:1903561) 1.896ATP1A3, TOR1A, GNAL, COL6A3, SLC2A1, TUBB4A
plasma membrane part (GO:0044459) 1.956ATP1A3, CACNA1B, HPCA, SLC2A1, DRD2, SGCE
extracellular region part (GO:0044421) 1.576ATP1A3, TOR1A, GNAL, COL6A3, SLC2A1, TUBB4A
synapse part (GO:0044456) 3.425ATP1A3, CACNA1B, DRD2, TOR1A, HPCA
nuclear part (GO:0044428) 1.555PRKRA, TAF1, THAP1, TOR1A, GCH1
extracellular exosome (GO:0070062) 1.895SLC2A1, COL6A3, TOR1A, GNAL, TUBB4A
cytoskeleton (GO:0005856) 2.554TUBB4A, SGCE, TOR1A, SLC2A1
plasma membrane region (GO:0098590) 2.974HPCA, SLC2A1, SGCE, DRD2
organelle membrane (GO:0031090) 1.974SLC2A1, DRD2, GCH1, TOR1A
cytoplasmic vesicle (GO:0031410) 2.874TOR1A, SLC2A1, GCH1, DRD2
nucleoplasm (GO:0005654) 1.894PRKRA, THAP1, TAF1, GCH1
intracellular vesicle (GO:0097708) 2.864TOR1A, SLC2A1, GCH1, DRD2
sarcolemma (GO:0042383) 5.23ATP1A3, COL6A3, SGCE
catalytic complex (GO:1902494) 2.93KCTD17, ATP1A3, TAF1
cytoplasmic, membrane-bounded vesicle (GO:0016023) 3.123SLC2A1, DRD2, TOR1A
cell projection membrane (GO:0031253) 4.113HPCA, SGCE, DRD2
dendrite (GO:0030425) 3.923CACNA1B, DRD2, SGCE
axon (GO:0030424) 4.153ATP1A3, DRD2, HPCA
plasma membrane protein complex (GO:0098797) 3.553ATP1A3, CACNA1B, SGCE
membrane protein complex (GO:0098796) 2.843ATP1A3, CACNA1B, SGCE
synapse (GO:0045202) 3.583ATP1A3, PRRT2, TOR1A
integral component of plasma membrane (GO:0005887) 2.573SLC2A1, DRD2, SGCE
intracellular (GO:0005622) 2.373SLC2A1, PRKRA, DRD2
intrinsic component of plasma membrane (GO:0031226) 2.533SLC2A1, DRD2, SGCE
cell junction (GO:0030054) 2.753SLC2A1, PRRT2, TOR1A
endoplasmic reticulum (GO:0005783) 2.563KCTD17, ATP1A3, TOR1A
transferase complex (GO:1990234) 3.322KCTD17, TAF1
membrane-enclosed lumen (GO:0031974) 3.052COL6A3, TOR1A
cilium (GO:0005929) 3.892TUBB4A, DRD2
dendritic spine head (GO:0044327) 7.612ATP1A3, HPCA
dendrite membrane (GO:0032590) 7.092HPCA, SGCE
perikaryon (GO:0043204) 5.132HPCA, DRD2
myelin sheath (GO:0043209) 4.762TUBB4A, ATP1A3
secretory granule (GO:0030141) 4.342TOR1A, DRD2
cytoplasmic vesicle part (GO:0044433) 3.412DRD2, TOR1A
endoplasmic reticulum part (GO:0044432) 2.732COL6A3, TOR1A
cytoskeletal part (GO:0044430) 2.492TUBB4A, SLC2A1
nucleoplasm part (GO:0044451) 3.222THAP1, TAF1
leading edge membrane (GO:0031256) 4.92HPCA, SGCE
neuronal cell body (GO:0043025) 3.92TUBB4A, CACNA1B
Golgi apparatus (GO:0005794) 2.72ATP1A3, SGCE
transmembrane transporter complex (GO:1902495) 4.062CACNA1B, ATP1A3
secretory vesicle (GO:0099503) 4.02DRD2, TOR1A
cell body (GO:0044297) 3.742TUBB4A, CACNA1B
bounding membrane of organelle (GO:0098588) 2.392SLC2A1, DRD2
transporter complex (GO:1990351) 4.042CACNA1B, ATP1A3
cytoplasmic vesicle membrane (GO:0030659) 3.672TOR1A, DRD2
neuron projection membrane (GO:0032589) 6.192HPCA, SGCE
endoplasmic reticulum lumen (GO:0005788) 4.52COL6A3, TOR1A
vesicle membrane (GO:0012506) 3.632TOR1A, DRD2
nuclear membrane (GO:0031965) 4.22TOR1A, GCH1
organelle lumen (GO:0043233) 3.052COL6A3, TOR1A
intracellular organelle lumen (GO:0070013) 3.052COL6A3, TOR1A
axon part (GO:0033267) 4.42TUBB4A, DRD2

NET-GE enrichment

Term New enriched termICP valueGenes
myelin sheath (GO:0043209) -4.760.014TUBB4A, ATP1A3
neuron part (GO:0097458) -2.640.01ATP1A3, TOR1A, CACNA1B, DRD2, SGCE, TUBB4A
cell projection part (GO:0044463) -2.970.033TOR1A, ATP1A3, SGCE, DRD2, TUBB4A
cell junction (GO:0030054) -2.750.027CACNA1B, TOR1A, GCH1, PRRT2, ATP1A3, DRD2, SLC2A1, TAF1, SGCE, TUBB4A