Gene table of ROR2 : receptor tyrosine kinase like orphan receptor 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ROR2	OMIM link	Number of associated genes	genes
113000	BRACHYDACTYLY, TYPE B1	ClinVar, OMIM	link to OMIM	1	ROR2
PS268310	ROBINOW SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	4	WNT5A, ROR2, DVL1, DVL3

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Annotation of the gene ROR2

Associated genes in ENSEMBL

ENSG00000169071

Associated proteins - SwissProt Accession ID

Q01974

Associated PDB IDs

Cytogenetic Band

9q22.31

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
beta-catenin independent WNT signaling	R-HSA-3858494	5.83
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	R-HSA-5140745	10.66
PCP/CE pathway	R-HSA-4086400	6.47
Signal Transduction	R-HSA-162582	1.78
Signaling by Wnt	R-HSA-195721	4.79

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
purine ribonucleoside triphosphate binding	GO:0035639	2.22
molecular transducer activity	GO:0060089	2.32
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
G-protein coupled receptor binding	GO:0001664	4.18
nucleotide binding	GO:0000166	1.96
Wnt-protein binding	GO:0017147	6.3
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
cation binding	GO:0043169	1.4
transferase activity	GO:0016740	1.95
ion binding	GO:0043167	1.36
transmembrane receptor protein tyrosine kinase activity	GO:0004714	5.55
purine nucleoside binding	GO:0001883	2.22
protein kinase activity	GO:0004672	3.27
purine nucleotide binding	GO:0017076	2.19
metal ion binding	GO:0046872	1.41
coreceptor activity	GO:0015026	6.1
ATP binding	GO:0005524	2.43
protein tyrosine kinase activity	GO:0004713	4.54
kinase activity	GO:0016301	2.93
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	GO:1904929	7.95
ribonucleoside binding	GO:0032549	2.22
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
coreceptor activity involved in Wnt signaling pathway	GO:0071936	7.66
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
frizzled binding	GO:0005109	6.1
transmembrane signaling receptor activity	GO:0004888	2.57
adenyl ribonucleotide binding	GO:0032559	2.41
transmembrane receptor activity	GO:0099600	2.53
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
receptor binding	GO:0005102	2.43
transmembrane receptor protein kinase activity	GO:0019199	5.32
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19
receptor activity	GO:0004872	2.32