| Disease ID | Disease name | Source of annotation with WNT5A | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS268310 | ROBINOW SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 4 | WNT5A, ROR2, DVL1, DVL3 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Signaling pathways regulating pluripotency of stem cells | hsa04550 | 5.6 |
| Hedgehog signaling pathway | hsa04340 | 7.01 |
| Proteoglycans in cancer | hsa05205 | 5.02 |
| Pathways in cancer | hsa05200 | 3.98 |
| Basal cell carcinoma | hsa05217 | 6.79 |
| Melanogenesis | hsa04916 | 5.97 |
| Hippo signaling pathway | hsa04390 | 5.37 |
| HTLV-I infection | hsa05166 | 4.59 |
| Wnt signaling pathway | hsa04310 | 5.49 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 6.52 |
| Signaling by Wnt | R-HSA-195721 | 4.79 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 7.01 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| beta-catenin independent WNT signaling | R-HSA-3858494 | 5.83 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 8.28 |
| PCP/CE pathway | R-HSA-4086400 | 6.47 |
| Ca2+ pathway | R-HSA-4086398 | 7.1 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 10.66 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 9.08 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 5.36 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 9.08 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| chemoattractant activity | GO:0042056 | 6.48 |
| cytokine activity | GO:0005125 | 4.34 |
| chemoattractant activity involved in axon guidance | GO:1902379 | 9.74 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| DNA binding | GO:0003677 | 1.92 |
| G-protein coupled receptor binding | GO:0001664 | 4.18 |
| molecular function regulator | GO:0098772 | 2.51 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| receptor regulator activity | GO:0030545 | 5.91 |
| receptor activator activity | GO:0030546 | 6.27 |
| receptor tyrosine kinase-like orphan receptor binding | GO:0005115 | 9.74 |
| nucleic acid binding | GO:0003676 | 1.44 |
| frizzled-2 binding | GO:0005110 | 9.05 |
| regulatory region nucleic acid binding | GO:0001067 | 3.03 |
| receptor agonist activity | GO:0048018 | 6.97 |
| protein domain specific binding | GO:0019904 | 3.32 |
| transcription regulatory region DNA binding | GO:0044212 | 3.03 |
| transcription factor activity, sequence-specific DNA binding | GO:0003700 | 2.65 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| frizzled binding | GO:0005109 | 6.1 |
| protein binding | GO:0005515 | 0.46 |
| regulatory region DNA binding | GO:0000975 | 3.03 |
| receptor binding | GO:0005102 | 2.43 |
| nucleic acid binding transcription factor activity | GO:0001071 | 2.65 |