Gene table of TRPM6 : transient receptor potential cation channel subfamily M member 6

Gene-disease associations table

Disease ID	Disease name	Source of annotation with TRPM6	OMIM link	Number of associated genes	genes
PS602014	HYPOMAGNESEMIA	ClinVar, OMIM, HUMSAVAR	link to OMIM	6	CLDN19, CLDN16, TRPM6, EGF, CNNM2, FXYD2

Download the gene annotation in CSV format

Annotation of the gene TRPM6

Associated genes in ENSEMBL

ENSG00000119121

Associated proteins - SwissProt Accession ID

Q9BX84

Associated PDB IDs

Cytogenetic Band

9q21.13

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Mineral absorption	hsa04978	7.09

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
TRP channels	R-HSA-3295583	8.18
Ion channel transport	R-HSA-983712	5.34
Transmembrane transport of small molecules	R-HSA-382551	3.79
Stimuli-sensing channels	R-HSA-2672351	6.28

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cation channel activity	GO:0005261	4.04
calcium channel activity	GO:0005262	5.03
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
nucleotide binding	GO:0000166	1.96
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
calcium ion transmembrane transporter activity	GO:0015085	4.89
ribonucleoside binding	GO:0032549	2.22
ion binding	GO:0043167	1.36
protein serine/threonine kinase activity	GO:0004674	3.64
transferase activity	GO:0016740	1.95
nucleoside phosphate binding	GO:1901265	1.96
protein kinase activity	GO:0004672	3.27
purine nucleotide binding	GO:0017076	2.19
metal ion transmembrane transporter activity	GO:0046873	3.71
metal ion binding	GO:0046872	1.41
ATP binding	GO:0005524	2.43
divalent inorganic cation transmembrane transporter activity	GO:0072509	4.62
cation transmembrane transporter activity	GO:0008324	3.32
cation binding	GO:0043169	1.4
transporter activity	GO:0005215	2.57
ion channel activity	GO:0005216	3.71
kinase activity	GO:0016301	2.93
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
passive transmembrane transporter activity	GO:0022803	3.6
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
ion transmembrane transporter activity	GO:0015075	3.04
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
transmembrane transporter activity	GO:0022857	2.82
channel activity	GO:0015267	3.6
adenyl ribonucleotide binding	GO:0032559	2.41
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
substrate-specific channel activity	GO:0022838	3.67
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19