Disease ID | Disease name | Source of annotation with VKORC1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
122700 | COUMARIN RESISTANCE | OMIM, HUMSAVAR | link to OMIM | 4 | CYP2A6, F9, CYP2C9, VKORC1 |
PS277450 | VITAMIN K-DEPENDENT CLOTTING FACTORS, COMBINED DEFICIENCY OF | ClinVar, OMIM, HUMSAVAR | link to OMIM | 2 | VKORC1, GGCX |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Ubiquinone and other terpenoid-quinone biosynthesis | hsa00130 | 9.45 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins | R-HSA-159854 | 9.52 |
Post-translational protein modification | R-HSA-597592 | 4.54 |
Gamma carboxylation, hypusine formation and arylsulfatase activation | R-HSA-163841 | 7.81 |
Metabolism of proteins | R-HSA-392499 | 3.41 |
GO term | GO ID | GO IC |
---|---|---|
vitamin-K-epoxide reductase (warfarin-sensitive) activity | GO:0047057 | 8.64 |
oxidoreductase activity, acting on CH-OH group of donors | GO:0016614 | 4.83 |
oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor | GO:0016900 | 8.64 |
catalytic activity | GO:0003824 | 1.05 |
cofactor binding | GO:0048037 | 4.16 |
binding | GO:0005488 | 0.18 |
quinone binding | GO:0048038 | 6.91 |
oxidoreductase activity | GO:0016491 | 3.12 |