Gene table of VKORC1 : vitamin K epoxide reductase complex subunit 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with VKORC1OMIM linkNumber of associated genesgenes
122700COUMARIN RESISTANCEOMIM, HUMSAVAR link to OMIM 4CYP2A6, F9, CYP2C9, VKORC1
PS277450VITAMIN K-DEPENDENT CLOTTING FACTORS, COMBINED DEFICIENCY OFClinVar, OMIM, HUMSAVAR link to OMIM 2VKORC1, GGCX

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Annotation of the gene VKORC1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Ubiquinone and other terpenoid-quinone biosynthesishsa001309.45
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Gamma-carboxylation, transport, and amino-terminal cleavage of proteinsR-HSA-1598549.52
Post-translational protein modificationR-HSA-5975924.54
Gamma carboxylation, hypusine formation and arylsulfatase activationR-HSA-1638417.81
Metabolism of proteinsR-HSA-3924993.41
Associated GO terms for Molecular function
GO termGO IDGO IC
vitamin-K-epoxide reductase (warfarin-sensitive) activityGO:00470578.64
oxidoreductase activity, acting on CH-OH group of donorsGO:00166144.83
oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptorGO:00169008.64
catalytic activityGO:00038241.05
cofactor bindingGO:00480374.16
bindingGO:00054880.18
quinone bindingGO:00480386.91
oxidoreductase activityGO:00164913.12