| cation binding | GO:0043169 | 1.4 |
| metal ion binding | GO:0046872 | 1.41 |
| protein binding | GO:0005515 | 0.46 |
| transcription factor activity, sequence-specific DNA binding | GO:0003700 | 2.65 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | GO:0003705 | 5.23 |
| phosphatase regulator activity | GO:0019208 | 5.26 |
| ion binding | GO:0043167 | 1.36 |
| SMAD binding | GO:0046332 | 5.45 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | GO:0001228 | 3.98 |
| R-SMAD binding | GO:0070412 | 6.65 |
| binding | GO:0005488 | 0.18 |
| nucleic acid binding | GO:0003676 | 1.44 |
| DNA binding | GO:0003677 | 1.92 |
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | GO:0001205 | 6.48 |
| molecular function regulator | GO:0098772 | 2.51 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | GO:0000981 | 3.29 |
| nucleic acid binding transcription factor activity | GO:0001071 | 2.65 |