| Disease ID | Disease name | Source of annotation with CDH1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 137215 | GASTRIC CANCER, HEREDITARY DIFFUSE | ClinVar, OMIM, HUMSAVAR | link to OMIM | 4 | IL1RN, CDH1, KRAS, IL1B |
| 114480 | BREAST CANCER | OMIM | link to OMIM | 27 | RB1CC1, ESR1, NBN, PALB2, SLC22A18, BRIP1, BCPR, CASP8, FAM175A, TSG101, CHEK2, BARD1, TP53, AKT1, BRCA1, RAD51, PHB, PPM1D, NQO2, ATM, PIK3CA, BRCA2, CDH1, XRCC3, HMMR, KRAS, RAD54L |
| 608089 | ENDOMETRIAL CANCER | OMIM | link to OMIM | 5 | MLH3, CDH1, MSH6, PTEN, MSH3 |
| 167000 | OVARIAN CANCER | OMIM | link to OMIM | 9 | AKT1, PARK2, CTNNB1, CDH1, BRCA1, RRAS2, PIK3CA, OPCML, SEPT9 |
| 176807 | PROSTATE CANCER | OMIM | link to OMIM | 15 | PTEN, EPHB2, KLF6, AR, HIP1, CD82, MXI1, BRCA2, CDH1, CHEK2, ZFHX3, MAD1L1, HOXB13, MSR1, FGFR4 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Melanoma | hsa05218 | 6.56 |
| Pathogenic Escherichia coli infection | hsa05130 | 6.99 |
| Bacterial invasion of epithelial cells | hsa05100 | 6.34 |
| Endometrial cancer | hsa05213 | 6.81 |
| Thyroid cancer | hsa05216 | 7.48 |
| Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
| Pathways in cancer | hsa05200 | 3.98 |
| Rap1 signaling pathway | hsa04015 | 4.97 |
| Adherens junction | hsa04520 | 6.26 |
| Hippo signaling pathway | hsa04390 | 5.37 |
| Bladder cancer | hsa05219 | 7.38 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Integrin cell surface interactions | R-HSA-216083 | 6.57 |
| Cell-cell junction organization | R-HSA-421270 | 7.03 |
| RHO GTPase Effectors | R-HSA-195258 | 4.94 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 7.73 |
| Apoptotic execution phase | R-HSA-75153 | 7.28 |
| Immune System | R-HSA-168256 | 2.37 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| Cell junction organization | R-HSA-446728 | 6.51 |
| Cell-Cell communication | R-HSA-1500931 | 5.87 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 6.11 |
| Programmed Cell Death | R-HSA-5357801 | 5.65 |
| Extracellular matrix organization | R-HSA-1474244 | 4.91 |
| RHO GTPases activate IQGAPs | R-HSA-5626467 | 8.34 |
| Adherens junctions interactions | R-HSA-418990 | 7.98 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 9.52 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| Apoptosis | R-HSA-109581 | 5.68 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.7 |
| GO term | GO ID | GO IC |
|---|---|---|
| glycoprotein binding | GO:0001948 | 5.11 |
| cation binding | GO:0043169 | 1.4 |
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| GTPase activating protein binding | GO:0032794 | 7.1 |
| gamma-catenin binding | GO:0045295 | 7.17 |
| beta-catenin binding | GO:0008013 | 5.3 |
| ion binding | GO:0043167 | 1.36 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| metal ion binding | GO:0046872 | 1.41 |
| ankyrin binding | GO:0030506 | 6.74 |
| calcium ion binding | GO:0005509 | 3.17 |