Disease table of VISCERAL MYOPATHY OMIM ID: 155310

Gene-disease associations table

GeneAssociated with VISCERAL MYOPATHY inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
MYH11ClinVarHGNC link16p13.113154700, 155310, PS607086
ACTG2ClinVar, OMIM, HUMSAVARHGNC link2p13.11155310

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
MYH11YES1KLF50
ACTG2YES1MYOCD0
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
MYH11ACTG2Yesbinding29TPM1, CALD1, MYH8, VCL, MYH7, MYH9, MYH3, MYL6B, TPM2, MYH2, MYH1, MYH14, TLN1, ITGB5, MYH6, SORBS3, ACTA2, MYH4, MYL9, PXN, MYL12B, MYH10, MYL6, SORBS1, TPM3, ITGA1, LMOD1, UBC, TPM4

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Vascular smooth muscle contractionhsa042705.742MYH11, ACTG2

NET-GE enrichment

Term New enriched termICP valueGenes
Hypertrophic cardiomyopathy (HCM) (hsa05410) NEW6.210.01MYH11, ACTG2
Circulatory systemNEW4.630.011MYH11, ACTG2
Vascular smooth muscle contraction (hsa04270) -5.740.002MYH11, ACTG2
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Muscle contractionR-HSA-3970146.962MYH11, ACTG2
Smooth Muscle ContractionR-HSA-4453558.232MYH11, ACTG2

NET-GE enrichment

Term New enriched termICP valueGenes
Muscle contraction (R-HSA-397014) -6.960.002MYH11, ACTG2
Smooth Muscle Contraction (R-HSA-445355) -8.230.0MYH11, ACTG2
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
adenyl nucleotide binding (GO:0030554) 2.42MYH11, ACTG2
purine ribonucleoside triphosphate binding (GO:0035639) 2.222MYH11, ACTG2
ATP binding (GO:0005524) 2.432MYH11, ACTG2
ribonucleotide binding (GO:0032553) 2.192MYH11, ACTG2
nucleotide binding (GO:0000166) 1.962MYH11, ACTG2
small molecule binding (GO:0036094) 1.892MYH11, ACTG2
carbohydrate derivative binding (GO:0097367) 2.032MYH11, ACTG2
purine ribonucleoside binding (GO:0032550) 2.222MYH11, ACTG2
adenyl ribonucleotide binding (GO:0032559) 2.412MYH11, ACTG2
binding (GO:0005488) 0.182MYH11, ACTG2
purine nucleoside binding (GO:0001883) 2.222MYH11, ACTG2
ribonucleoside binding (GO:0032549) 2.222MYH11, ACTG2
purine ribonucleotide binding (GO:0032555) 2.22MYH11, ACTG2
purine nucleotide binding (GO:0017076) 2.192MYH11, ACTG2
organic cyclic compound binding (GO:0097159) 1.052MYH11, ACTG2
heterocyclic compound binding (GO:1901363) 1.062MYH11, ACTG2
nucleoside phosphate binding (GO:1901265) 1.962MYH11, ACTG2
nucleoside binding (GO:0001882) 2.212MYH11, ACTG2
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
muscle system process (GO:0003012) 4.182MYH11, ACTG2
multicellular organismal process (GO:0032501) 1.452MYH11, ACTG2
muscle contraction (GO:0006936) 4.372MYH11, ACTG2
single-organism process (GO:0044699) 0.482MYH11, ACTG2
system process (GO:0003008) 2.32MYH11, ACTG2

NET-GE enrichment

Term New enriched termICP valueGenes
muscle contraction (GO:0006936) -4.370.005MYH11, ACTG2
muscle system process (GO:0003012) -4.180.008MYH11, ACTG2
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
protein complex (GO:0043234) 1.512MYH11, ACTG2
myosin complex (GO:0016459) 5.552MYH11, ACTG2
myosin filament (GO:0032982) 6.712MYH11, ACTG2
extracellular exosome (GO:0070062) 1.892MYH11, ACTG2
extracellular region part (GO:0044421) 1.572MYH11, ACTG2
cytosol (GO:0005829) 1.682MYH11, ACTG2
cell part (GO:0044464) 0.112MYH11, ACTG2
cytoplasmic part (GO:0044444) 0.822MYH11, ACTG2
membrane-bounded vesicle (GO:0031988) 1.712MYH11, ACTG2
intracellular organelle part (GO:0044446) 0.812MYH11, ACTG2
extracellular organelle (GO:0043230) 1.892MYH11, ACTG2
intracellular organelle (GO:0043229) 0.512MYH11, ACTG2
cytoskeletal part (GO:0044430) 2.492MYH11, ACTG2
intracellular part (GO:0044424) 0.282MYH11, ACTG2
macromolecular complex (GO:0032991) 1.352MYH11, ACTG2
extracellular vesicle (GO:1903561) 1.892MYH11, ACTG2
membrane-bounded organelle (GO:0043227) 0.472MYH11, ACTG2
organelle (GO:0043226) 0.42MYH11, ACTG2
organelle part (GO:0044422) 0.792MYH11, ACTG2
vesicle (GO:0031982) 1.642MYH11, ACTG2