Disease table of PROLONGED ELECTRORETINAL RESPONSE SUPPRESSION OMIM ID: 608415

Gene-disease associations table

GeneAssociated with PROLONGED ELECTRORETINAL RESPONSE SUPPRESSION inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
RGS9ClinVar, OMIM, HUMSAVARHGNC link17q24.11608415
RGS9BPOMIMHGNC link19q13.111608415

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
RGS9RGS9BPYes0

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
RGS9RGS9BPYesbinding8GNB5, PDE6B, PDE6H, PDE6A, PDE6G, PDE6C, GNAT2, GNAT1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
Gene1Gene2Direct interactionMore information
RGS9RGS9BPyes, they interactThe isoform 3 of RGS9 is targeted to the membrane via its interaction with RGS9BP. [UniProt]
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
The phototransduction cascadeR-HSA-25148568.032RGS9BP, RGS9
Visual phototransductionR-HSA-21873386.442RGS9BP, RGS9
Signal TransductionR-HSA-1625821.782RGS9BP, RGS9
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-25148598.082RGS9BP, RGS9

NET-GE enrichment

Term New enriched termICP valueGenes
The phototransduction cascade (R-HSA-2514856) -8.030.0RGS9BP, RGS9
Inactivation, recovery and regulation of the phototransduction cascade (R-HSA-2514859) -8.080.0RGS9BP, RGS9
Visual phototransduction (R-HSA-2187338) -6.440.001RGS9BP, RGS9
GO - molecular function annotation: shared terms / NET-GE enrichment (no shared terms)
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
response to stimulus (GO:0050896) 1.222RGS9BP, RGS9
multicellular organismal process (GO:0032501) 1.452RGS9BP, RGS9
negative regulation of signal transduction (GO:0009968) 2.752RGS9BP, RGS9
regulation of signal transduction (GO:0009966) 1.842RGS9BP, RGS9
neurological system process (GO:0050877) 2.642RGS9BP, RGS9
negative regulation of response to stimulus (GO:0048585) 2.522RGS9BP, RGS9
regulation of response to stimulus (GO:0048583) 1.542RGS9BP, RGS9
sensory perception (GO:0007600) 2.932RGS9BP, RGS9
sensory perception of light stimulus (GO:0050953) 4.42RGS9BP, RGS9
regulation of cellular process (GO:0050794) 0.52RGS9BP, RGS9
visual perception (GO:0007601) 4.412RGS9BP, RGS9
negative regulation of signaling (GO:0023057) 2.652RGS9BP, RGS9
biological regulation (GO:0065007) 0.392RGS9BP, RGS9
negative regulation of cell communication (GO:0010648) 2.662RGS9BP, RGS9
regulation of signaling (GO:0023051) 1.722RGS9BP, RGS9
negative regulation of biological process (GO:0048519) 1.332RGS9BP, RGS9
regulation of cell communication (GO:0010646) 1.732RGS9BP, RGS9
regulation of biological process (GO:0050789) 0.452RGS9BP, RGS9
negative regulation of cellular process (GO:0048523) 1.412RGS9BP, RGS9
system process (GO:0003008) 2.32RGS9BP, RGS9

NET-GE enrichment

Term New enriched termICP valueGenes
detection of external stimulus (GO:0009581) NEW4.980.008RGS9BP, RGS9
detection of abiotic stimulus (GO:0009582) NEW4.960.008RGS9BP, RGS9
cellular response to radiation (GO:0071478) NEW4.810.004RGS9BP, RGS9
detection of visible light (GO:0009584) NEW6.230.022RGS9BP, RGS9
rhodopsin mediated signaling pathway (GO:0016056) NEW7.240.001RGS9BP, RGS9
phototransduction, visible light (GO:0007603) NEW7.530.002RGS9BP, RGS9
phototransduction (GO:0007602) NEW5.990.023RGS9BP, RGS9
regulation of G-protein coupled receptor protein signaling pathway (GO:0008277) NEW4.970.027RGS9BP, RGS9
detection of light stimulus (GO:0009583) NEW5.670.004RGS9BP, RGS9
response to light stimulus (GO:0009416) NEW4.080.027RGS9BP, RGS9
regulation of rhodopsin mediated signaling pathway (GO:0022400) NEW6.470.0RGS9BP, RGS9
cellular response to light stimulus (GO:0071482) NEW5.220.007RGS9BP, RGS9
cellular response to abiotic stimulus (GO:0071214) NEW4.150.014RGS9BP, RGS9
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
primary cilium (GO:0072372) 4.642RGS9BP, RGS9
membrane (GO:0016020) 0.682RGS9BP, RGS9
cell part (GO:0044464) 0.112RGS9BP, RGS9
photoreceptor outer segment (GO:0001750) 5.782RGS9BP, RGS9
nonmotile primary cilium (GO:0031513) 5.142RGS9BP, RGS9
neuron part (GO:0097458) 2.642RGS9BP, RGS9
cilium (GO:0005929) 3.892RGS9BP, RGS9
membrane part (GO:0044425) 0.952RGS9BP, RGS9
cell projection (GO:0042995) 2.472RGS9BP, RGS9
organelle (GO:0043226) 0.42RGS9BP, RGS9