Gene | Associated with TRIGONOCEPHALY, ISOLATED in | Link to HGNC | Cytogenetic band | Number of associated diseases | Associated diseases |
---|---|---|---|---|---|
FREM1 | ClinVar, OMIM, HUMSAVAR | HGNC link | 9p22.3 | 4 | 608980, 142340, PS190440, 248450 |
FGFR1 | ClinVar, OMIM, HUMSAVAR | HGNC link | 8p11.23 | 7 | 166250, PS147950, 101600, 613001, PS190440, 615465, 123150 |
Download the disease annotation in CSV format
regulated gene | associated to this disease | # TFs | TFs | # TFs associated with this disease | TFs associated with this disease |
---|---|---|---|---|---|
FGFR1 | YES | 4 | SP1, RB1, KLF10, E2F1 | 0 |
Gene1 | Gene2 | Direct Interaction | Interaction mode | Number of shared interactors | Shared genes in interaction |
---|---|---|---|---|---|
FREM1 | FGFR1 | No | - | 1 | PDGFC |
Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)
GO | IC | Number of genes with the same GO | Genes |
---|---|---|---|
binding (GO:0005488) | 0.18 | 2 | FREM1, FGFR1 |
GO | IC | Number of genes with the same GO | Genes |
---|---|---|---|
membrane part (GO:0044425) | 0.95 | 2 | FREM1, FGFR1 |
integral component of membrane (GO:0016021) | 1.14 | 2 | FREM1, FGFR1 |
extracellular region (GO:0005576) | 2.18 | 2 | FREM1, FGFR1 |
intrinsic component of membrane (GO:0031224) | 1.13 | 2 | FREM1, FGFR1 |