Disease table of ROBINOW SYNDROME OMIM ID: PS268310

Gene-disease associations table

GeneAssociated with ROBINOW SYNDROME inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
DVL3ClinVar, OMIMHGNC link3q27.11PS268310
WNT5AClinVar, OMIM, HUMSAVARHGNC link3p14.31PS268310
DVL1OMIMHGNC link1p36.331PS268310
ROR2ClinVar, OMIM, HUMSAVARHGNC link9q22.312113000, PS268310

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
32WNT5A, DVL3
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
WNT5AYES3HOXB7, CUX1, PITX20
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
DVL3DVL1Yes24WWOX, CSNK1E, SSX2IP, NUMA1, XPO1, RASSF10, CSNK1D, CEP135, CEP128, AXIN1, WWTR1, DVL3, DAB2, CTNNB1, LRRK2, CEP19, RASSF9, CEP44, DVL1, CYLD, CSNK2A1, HUWE1, DVL2, ITCH
DVL3ROR2No2NTRK1, NXF1
DVL1ROR2No1TMEM17

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
DVL3WNT5AYesactivation, binding43RAC1, WNT1, LRP5, SFRP1, WNT2B, FZD1, MAPK10, WNT8A, DVL2, NOTCH3, WNT9A, FZD3, WNT16, MAPK8, FZD2, AXIN1, ROR2, FZD8, WNT3, WNT8B, FZD4, LRP6, WNT5B, WNT7A, MAPK9, NOTCH1, DVL1, AXIN2, WNT11, GSK3B, FZD6, FZD5, FZD10, WNT3A, WNT2, VANGL2, FZD7, WNT9B, PTK7, TCF7L2, WNT7B, MYC, WNT4
DVL3DVL1Yesactivation, binding136WNT9A, PSMC4, RHOC, PSMD6, LRP5, FZD1, MAPK10, CDC42, NKD2, PSMD1, WNT11, NKD1, PSMB5, GNAO1, CTHRC1, WNT1, PSMD10, CTNNB1, GSK3A, UBA52, PSMB1, VANGL2, ABL1, FZD4, PSME3, PSMD9, WNT2, TIAM1, PSMA8, FZD6, WNT9B, FHL3, CUL3, RAC3, FRAT1, GNAQ, CSNK1E, LMO7, WNT8A, UBB, MAPK8, DACT1, RHOA, PSME1, ROR2, PRICKLE3, PSMD3, PSMD4, PI4K2A, CSNK1G2, PSMA7, MAPK9, LPXN, ABL2, WNT3, PSME4, PSMC5, FZD7, PIP5K1B, VANGL1, UBC, ANKRD6, PSMA3, NOTCH4, PSMC6, WNT5A, SFRP1, RAC1, TGFB1I1, CSNK1D, FZD3, FRAT2, PSMA5, PSMD11, DAAM2, AXIN1, LRRFIP2, LRP6, PRICKLE1, FHL5, NOTCH1, SENP2, KLHL12, PSMB10, PXN, PSME2, PSMD12, PSMD7, CSNK2A1, WNT7A, PRICKLE2, WNT4, CSNK2A2, WNT2B, PSMC1, PSMB3, PSMB11, WNT7B, DVL2, PSMC3, DAAM1, BAMBI, PSMF1, WNT5B, PSMB2, RPS27A, RHOB, LRRK2, PSMC2, PSMB4, PTK7, FZD8, WNT8B, WNT3A, PSMA1, PSMD5, WNT16, PSMB6, PSMA4, PSMA6, NOTCH3, JUP, AXIN2, APC2, PSMD14, PSMD8, PSMD2, GSK3B, FZD5, FZD10, CSNK1G1, FZD2, PSMD13, PRICKLE4, CXXC4, PSMB7
DVL3ROR2Yesactivation, binding26RAC1, LRP5, SFRP1, WNT2B, MAPK10, WNT7B, DVL2, WNT3A, WNT5B, MAPK8, FZD2, CTHRC1, WNT1, FZD4, WNT5A, WNT16, FZD5, MAPK9, DVL1, FZD6, WNT3, WNT2, VANGL2, FZD7, WNT7A, WNT4
WNT5ADVL1Yesactivation, binding45WNT2B, WNT1, LRP5, SFRP1, RAC1, FZD1, WNT10B, WNT8A, DVL2, NOTCH3, WNT9A, FZD3, WNT16, MAPK8, FZD2, FRZB, AXIN1, ROR2, FZD8, WNT3, WNT8B, FZD4, DVL3, LRP6, WNT5B, MAPK9, NOTCH1, VANGL2, AXIN2, WNT11, GSK3B, FZD6, FZD5, FZD10, WNT3A, WNT2, MAPK10, FZD7, WNT9B, PTK7, WNT4, WNT7A, WNT7B, ARRB2, SFRP2
WNT5AROR2Yesactivation, binding33RAC1, LRP5, SFRP1, WNT2B, MAPK10, WNT7B, DVL2, WNT3A, WNT16, CLTC, FZD2, ARRB2, WNT3, WNT1, FZD4, DVL3, WNT5B, AP2A2, MAPK9, MAPK8, VANGL2, AP2M1, FZD6, FZD5, AP2S1, WNT2, DVL1, FZD7, WNT6, WNT4, WNT7A, AP2B1, AP2A1
DVL1ROR2Yesactivation, binding27WNT2B, LRP5, SFRP1, RAC1, MAPK10, WNT7B, DVL2, WNT3A, WNT16, MAPK8, FZD2, ARRB2, CTHRC1, WNT1, FZD4, DVL3, WNT5A, WNT5B, FZD5, MAPK9, VANGL2, FZD6, WNT3, WNT2, FZD7, WNT7A, WNT4

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Signaling pathways regulating pluripotency of stem cellshsa045505.63DVL1, DVL3, WNT5A
Pathways in cancerhsa052003.983DVL1, DVL3, WNT5A
Basal cell carcinomahsa052176.793DVL1, DVL3, WNT5A
Hippo signaling pathwayhsa043905.373DVL1, DVL3, WNT5A
Melanogenesishsa049165.973DVL1, DVL3, WNT5A
HTLV-I infectionhsa051664.593DVL1, DVL3, WNT5A
Wnt signaling pathwayhsa043105.493DVL1, DVL3, WNT5A
Notch signaling pathwayhsa043307.122DVL3, DVL1

NET-GE enrichment

Term New enriched termICP valueGenes
Signaling pathways regulating pluripotency of stem cells (hsa04550) -5.60.0DVL1, DVL3, WNT5A, ROR2
Cancers: Specific typesNEW4.10.003DVL1, DVL3, WNT5A, ROR2
Proteoglycans in cancer (hsa05205) NEW5.020.0DVL1, DVL3, WNT5A, ROR2
Infectious diseases: ViralNEW3.290.022DVL1, DVL3, WNT5A
Pathways in cancer (hsa05200) -3.980.005DVL1, DVL3, WNT5A, ROR2
Basal cell carcinoma (hsa05217) -6.790.0DVL1, DVL3, WNT5A, ROR2
Notch signaling pathway (hsa04330) -7.120.011DVL3, DVL1
Hedgehog signaling pathway (hsa04340) NEW7.010.019WNT5A, ROR2
Hippo signaling pathway (hsa04390) -5.370.0DVL1, DVL3, WNT5A, ROR2
Endocrine systemNEW3.260.024DVL1, DVL3, WNT5A
Cellular communityNEW3.570.02DVL1, DVL3, WNT5A, ROR2
Melanogenesis (hsa04916) -5.970.0DVL1, DVL3, WNT5A, ROR2
HTLV-I infection (hsa05166) -4.590.001DVL1, DVL3, WNT5A, ROR2
Wnt signaling pathway (hsa04310) -5.490.0DVL1, DVL3, WNT5A, ROR2
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
beta-catenin independent WNT signalingR-HSA-38584945.834DVL1, DVL3, WNT5A, ROR2
Signaling by WntR-HSA-1957214.794DVL1, DVL3, WNT5A, ROR2
PCP/CE pathwayR-HSA-40864006.474DVL1, DVL3, WNT5A, ROR2
Signal TransductionR-HSA-1625821.784DVL1, DVL3, WNT5A, ROR2
TCF dependent signaling in response to WNTR-HSA-2016815.363DVL1, DVL3, WNT5A
RHO GTPase EffectorsR-HSA-1952584.942DVL3, DVL1
negative regulation of TCF-dependent signaling by DVL-interacting proteinsR-HSA-536859810.662DVL3, DVL1
Signaling by Rho GTPasesR-HSA-1943154.432DVL3, DVL1
RHO GTPases Activate ForminsR-HSA-56632206.012DVL3, DVL1
WNT mediated activation of DVLR-HSA-2016889.982DVL3, DVL1
WNT5A-dependent internalization of FZD2, FZD5 and ROR2R-HSA-514074510.662WNT5A, ROR2
disassembly of the destruction complex and recruitment of AXIN to the membraneR-HSA-46412628.032DVL3, DVL1
degradation of DVLR-HSA-46412587.182DVL3, DVL1

NET-GE enrichment

Term New enriched termICP valueGenes
Extracellular matrix organization (R-HSA-1474244) NEW4.910.046DVL1, DVL3, WNT5A
Class B/2 (Secretin family receptors) (R-HSA-373080) NEW6.520.001DVL3, WNT5A, ROR2
RHO GTPases Activate Formins (R-HSA-5663220) -6.010.031DVL3, DVL1
Asymmetric localization of PCP proteins (R-HSA-4608870) NEW7.010.016WNT5A, DVL1
Signaling by Wnt (R-HSA-195721) -4.790.0DVL1, DVL3, WNT5A, ROR2
TCF dependent signaling in response to WNT (R-HSA-201681) -5.360.001DVL1, DVL3, WNT5A, ROR2
beta-catenin independent WNT signaling (R-HSA-3858494) -5.830.0DVL1, DVL3, WNT5A, ROR2
WNT ligand biogenesis and trafficking (R-HSA-3238698) NEW8.280.0DVL3, WNT5A, ROR2
PCP/CE pathway (R-HSA-4086400) -6.470.0DVL1, DVL3, WNT5A, ROR2
negative regulation of TCF-dependent signaling by DVL-interacting proteins (R-HSA-5368598) -10.660.0DVL3, DVL1
Activation of Matrix Metalloproteinases (R-HSA-1592389) NEW8.030.016DVL3, DVL1
Ca2+ pathway (R-HSA-4086398) NEW7.10.0DVL1, DVL3, WNT5A
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (R-HSA-5140745) -10.660.0WNT5A, ROR2
WNT mediated activation of DVL (R-HSA-201688) -9.980.0DVL3, DVL1
disassembly of the destruction complex and recruitment of AXIN to the membrane (R-HSA-4641262) -8.030.002DVL3, DVL1
Assembly of collagen fibrils and other multimeric structures (R-HSA-2022090) NEW7.20.04WNT5A, DVL1
GPCR ligand binding (R-HSA-500792) NEW4.190.002DVL1, DVL3, WNT5A, ROR2
degradation of DVL (R-HSA-4641258) -7.180.011DVL3, DVL1
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
G-protein coupled receptor binding (GO:0001664) 4.184DVL1, DVL3, WNT5A, ROR2
receptor binding (GO:0005102) 2.434DVL1, DVL3, WNT5A, ROR2
binding (GO:0005488) 0.184DVL1, DVL3, WNT5A, ROR2
protein binding (GO:0005515) 0.464DVL1, DVL3, WNT5A, ROR2
frizzled binding (GO:0005109) 6.14DVL1, DVL3, WNT5A, ROR2
enzyme binding (GO:0019899) 2.272DVL3, DVL1
organic cyclic compound binding (GO:0097159) 1.052WNT5A, ROR2
Rac GTPase binding (GO:0048365) 6.052DVL3, DVL1
Rho GTPase binding (GO:0017048) 5.362DVL3, DVL1
Ras GTPase binding (GO:0017016) 4.22DVL3, DVL1
small GTPase binding (GO:0031267) 4.132DVL3, DVL1
GTPase binding (GO:0051020) 4.052DVL3, DVL1
beta-catenin binding (GO:0008013) 5.32DVL3, DVL1
signal transducer activity (GO:0004871) 2.282WNT5A, ROR2
heterocyclic compound binding (GO:1901363) 1.062WNT5A, ROR2

NET-GE enrichment

Term New enriched termICP valueGenes
phosphotransferase activity, alcohol group as acceptor (GO:0016773) NEW3.080.022DVL1, DVL3, WNT5A, ROR2
kinase activity (GO:0016301) NEW2.930.034DVL1, DVL3, WNT5A, ROR2
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (GO:0001228) NEW3.980.023DVL1, DVL3, WNT5A
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity (GO:0000982) NEW3.940.024DVL1, DVL3, WNT5A
frizzled binding (GO:0005109) -6.10.0DVL1, DVL3, WNT5A, ROR2
PDZ domain binding (GO:0030165) NEW5.220.002DVL1, DVL3, WNT5A
protein kinase activity (GO:0004672) NEW3.270.012DVL1, DVL3, WNT5A, ROR2
Wnt-protein binding (GO:0017147) NEW6.30.006WNT5A, ROR2
G-protein coupled receptor binding (GO:0001664) -4.180.0DVL1, DVL3, WNT5A, ROR2
receptor binding (GO:0005102) -2.430.002DVL1, DVL3, WNT5A, ROR2
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
negative regulation of canonical Wnt signaling pathway (GO:0090090) 4.634DVL1, DVL3, WNT5A, ROR2
Wnt signaling pathway (GO:0016055) 3.884DVL1, DVL3, WNT5A, ROR2
positive regulation of metabolic process (GO:0009893) 1.744DVL1, DVL3, WNT5A, ROR2
regulation of metabolic process (GO:0019222) 1.024DVL1, DVL3, WNT5A, ROR2
positive regulation of biosynthetic process (GO:0009891) 2.294DVL1, DVL3, WNT5A, ROR2
regulation of cellular biosynthetic process (GO:0031326) 1.384DVL1, DVL3, WNT5A, ROR2
positive regulation of cell communication (GO:0010647) 2.414DVL1, DVL3, WNT5A, ROR2
positive regulation of response to stimulus (GO:0048584) 2.184DVL1, DVL3, WNT5A, ROR2
regulation of response to stimulus (GO:0048583) 1.544DVL1, DVL3, WNT5A, ROR2
positive regulation of RNA metabolic process (GO:0051254) 2.514DVL1, DVL3, WNT5A, ROR2
positive regulation of signaling (GO:0023056) 2.414DVL1, DVL3, WNT5A, ROR2
negative regulation of signaling (GO:0023057) 2.654DVL1, DVL3, WNT5A, ROR2
regulation of Wnt signaling pathway (GO:0030111) 3.984DVL1, DVL3, WNT5A, ROR2
positive regulation of gene expression (GO:0010628) 2.354DVL1, DVL3, WNT5A, ROR2
positive regulation of cellular biosynthetic process (GO:0031328) 2.34DVL1, DVL3, WNT5A, ROR2
signal transduction (GO:0007165) 1.284DVL1, DVL3, WNT5A, ROR2
cell surface receptor signaling pathway (GO:0007166) 2.094DVL1, DVL3, WNT5A, ROR2
regulation of signaling (GO:0023051) 1.724DVL1, DVL3, WNT5A, ROR2
single-organism developmental process (GO:0044767) 1.494DVL1, DVL3, WNT5A, ROR2
intracellular signal transduction (GO:0035556) 2.394DVL1, DVL3, WNT5A, ROR2
anatomical structure morphogenesis (GO:0009653) 2.534DVL1, DVL3, WNT5A, ROR2
multicellular organism development (GO:0007275) 2.544DVL1, DVL3, WNT5A, ROR2
single-organism process (GO:0044699) 0.484DVL1, DVL3, WNT5A, ROR2
regulation of primary metabolic process (GO:0080090) 1.084DVL1, DVL3, WNT5A, ROR2
negative regulation of cell communication (GO:0010648) 2.664DVL1, DVL3, WNT5A, ROR2
regulation of cell communication (GO:0010646) 1.734DVL1, DVL3, WNT5A, ROR2
positive regulation of macromolecule metabolic process (GO:0010604) 1.814DVL1, DVL3, WNT5A, ROR2
negative regulation of signal transduction (GO:0009968) 2.754DVL1, DVL3, WNT5A, ROR2
regulation of signal transduction (GO:0009966) 1.844DVL1, DVL3, WNT5A, ROR2
positive regulation of signal transduction (GO:0009967) 2.54DVL1, DVL3, WNT5A, ROR2
regulation of anatomical structure morphogenesis (GO:0022603) 2.794DVL1, DVL3, WNT5A, ROR2
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.464DVL1, DVL3, WNT5A, ROR2
regulation of biological process (GO:0050789) 0.454DVL1, DVL3, WNT5A, ROR2
positive regulation of nucleic acid-templated transcription (GO:1903508) 2.564DVL1, DVL3, WNT5A, ROR2
regulation of developmental process (GO:0050793) 2.14DVL1, DVL3, WNT5A, ROR2
biological regulation (GO:0065007) 0.394DVL1, DVL3, WNT5A, ROR2
positive regulation of transcription, DNA-templated (GO:0045893) 2.564DVL1, DVL3, WNT5A, ROR2
positive regulation of biological process (GO:0048518) 1.24DVL1, DVL3, WNT5A, ROR2
negative regulation of biological process (GO:0048519) 1.334DVL1, DVL3, WNT5A, ROR2
positive regulation of nitrogen compound metabolic process (GO:0051173) 2.294DVL1, DVL3, WNT5A, ROR2
negative regulation of response to stimulus (GO:0048585) 2.524DVL1, DVL3, WNT5A, ROR2
embryonic morphogenesis (GO:0048598) 3.724DVL1, DVL3, WNT5A, ROR2
multicellular organismal process (GO:0032501) 1.454DVL1, DVL3, WNT5A, ROR2
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 2.354DVL1, DVL3, WNT5A, ROR2
negative regulation of Wnt signaling pathway (GO:0030178) 4.444DVL1, DVL3, WNT5A, ROR2
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.434DVL1, DVL3, WNT5A, ROR2
regulation of cellular metabolic process (GO:0031323) 1.074DVL1, DVL3, WNT5A, ROR2
cellular process (GO:0009987) 0.264DVL1, DVL3, WNT5A, ROR2
regulation of biosynthetic process (GO:0009889) 1.374DVL1, DVL3, WNT5A, ROR2
regulation of nucleic acid-templated transcription (GO:1903506) 1.554DVL1, DVL3, WNT5A, ROR2
regulation of cellular process (GO:0050794) 0.54DVL1, DVL3, WNT5A, ROR2
(GO:1905330) 4.564DVL1, DVL3, WNT5A, ROR2
single-organism cellular process (GO:0044763) 0.654DVL1, DVL3, WNT5A, ROR2
regulation of nitrogen compound metabolic process (GO:0051171) 1.364DVL1, DVL3, WNT5A, ROR2
regulation of multicellular organismal process (GO:0051239) 1.874DVL1, DVL3, WNT5A, ROR2
regulation of RNA biosynthetic process (GO:2001141) 1.554DVL1, DVL3, WNT5A, ROR2
regulation of localization (GO:0032879) 1.944DVL1, DVL3, WNT5A, ROR2
non-canonical Wnt signaling pathway (GO:0035567) 4.794DVL1, DVL3, WNT5A, ROR2
Wnt signaling pathway, planar cell polarity pathway (GO:0060071) 5.124DVL1, DVL3, WNT5A, ROR2
single-multicellular organism process (GO:0044707) 1.784DVL1, DVL3, WNT5A, ROR2
regulation of establishment of planar polarity (GO:0090175) 5.024DVL1, DVL3, WNT5A, ROR2
regulation of macromolecule metabolic process (GO:0060255) 1.084DVL1, DVL3, WNT5A, ROR2
anatomical structure development (GO:0048856) 1.584DVL1, DVL3, WNT5A, ROR2
regulation of canonical Wnt signaling pathway (GO:0060828) 4.264DVL1, DVL3, WNT5A, ROR2
positive regulation of cellular metabolic process (GO:0031325) 1.814DVL1, DVL3, WNT5A, ROR2
regulation of gene expression (GO:0010468) 1.374DVL1, DVL3, WNT5A, ROR2
positive regulation of RNA biosynthetic process (GO:1902680) 2.544DVL1, DVL3, WNT5A, ROR2
regulation of transcription, DNA-templated (GO:0006355) 1.564DVL1, DVL3, WNT5A, ROR2
positive regulation of macromolecule biosynthetic process (GO:0010557) 2.394DVL1, DVL3, WNT5A, ROR2
regulation of macromolecule biosynthetic process (GO:0010556) 1.434DVL1, DVL3, WNT5A, ROR2
regulation of multicellular organismal development (GO:2000026) 2.314DVL1, DVL3, WNT5A, ROR2
regulation of organ morphogenesis (GO:2000027) 4.224DVL1, DVL3, WNT5A, ROR2
cell surface receptor signaling pathway involved in cell-cell signaling (GO:1905114) 3.794DVL1, DVL3, WNT5A, ROR2
regulation of RNA metabolic process (GO:0051252) 1.524DVL1, DVL3, WNT5A, ROR2
developmental process (GO:0032502) 1.364DVL1, DVL3, WNT5A, ROR2
negative regulation of cellular process (GO:0048523) 1.414DVL1, DVL3, WNT5A, ROR2
positive regulation of cellular process (GO:0048522) 1.34DVL1, DVL3, WNT5A, ROR2
positive regulation of protein modification process (GO:0031401) 2.73DVL1, DVL3, WNT5A
regulation of phosphate metabolic process (GO:0019220) 2.353DVL1, DVL3, WNT5A
metabolic process (GO:0008152) 0.583WNT5A, DVL1, ROR2
regulation of cellular localization (GO:0060341) 3.033DVL1, DVL3, WNT5A
positive regulation of protein phosphorylation (GO:0001934) 2.953DVL1, DVL3, WNT5A
regulation of cellular protein localization (GO:1903827) 3.433DVL1, DVL3, WNT5A
positive regulation of Wnt signaling pathway (GO:0030177) 4.73WNT5A, DVL1, ROR2
cellular metabolic process (GO:0044237) 0.693WNT5A, DVL1, ROR2
cellular component organization or biogenesis (GO:0071840) 1.223DVL1, DVL3, WNT5A
regulation of protein localization (GO:0032880) 2.883DVL1, DVL3, WNT5A
cochlea morphogenesis (GO:0090103) 6.643DVL1, DVL3, WNT5A
cellular macromolecule metabolic process (GO:0044260) 0.933WNT5A, DVL1, ROR2
cellular developmental process (GO:0048869) 1.823WNT5A, DVL1, ROR2
positive regulation of phosphorus metabolic process (GO:0010562) 2.783DVL1, DVL3, WNT5A
regulation of kinase activity (GO:0043549) 3.073DVL1, DVL3, WNT5A
regulation of protein metabolic process (GO:0051246) 1.933DVL1, DVL3, WNT5A
positive regulation of protein metabolic process (GO:0051247) 2.433DVL1, DVL3, WNT5A
cellular component organization (GO:0016043) 1.243DVL1, DVL3, WNT5A
organic substance metabolic process (GO:0071704) 0.633WNT5A, DVL1, ROR2
positive regulation of cellular protein metabolic process (GO:0032270) 2.493DVL1, DVL3, WNT5A
regulation of protein modification process (GO:0031399) 2.323DVL1, DVL3, WNT5A
regulation of molecular function (GO:0065009) 1.783DVL1, DVL3, WNT5A
organ morphogenesis (GO:0009887) 3.553DVL3, WNT5A, ROR2
regulation of catalytic activity (GO:0050790) 1.973DVL1, DVL3, WNT5A
positive regulation of phosphate metabolic process (GO:0045937) 2.783DVL1, DVL3, WNT5A
regulation of protein kinase activity (GO:0045859) 3.153DVL1, DVL3, WNT5A
regulation of phosphorus metabolic process (GO:0051174) 2.353DVL1, DVL3, WNT5A
canonical Wnt signaling pathway (GO:0060070) 5.263DVL1, DVL3, WNT5A
regulation of embryonic development (GO:0045995) 4.983DVL1, DVL3, WNT5A
regulation of phosphorylation (GO:0042325) 2.53DVL1, DVL3, WNT5A
primary metabolic process (GO:0044238) 0.693WNT5A, DVL1, ROR2
positive regulation of phosphorylation (GO:0042327) 2.93DVL1, DVL3, WNT5A
regulation of cellular protein metabolic process (GO:0032268) 1.993DVL1, DVL3, WNT5A
planar cell polarity pathway involved in neural tube closure (GO:0090179) 7.163DVL1, DVL3, WNT5A
regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) 7.023DVL1, DVL3, WNT5A
regulation of transferase activity (GO:0051338) 2.883DVL1, DVL3, WNT5A
macromolecule metabolic process (GO:0043170) 0.833WNT5A, DVL1, ROR2
regulation of nervous system development (GO:0051960) 3.13DVL1, DVL3, WNT5A
(GO:1905276) 6.783DVL1, DVL3, WNT5A
regulation of protein phosphorylation (GO:0001932) 2.573DVL1, DVL3, WNT5A
response to stimulus (GO:0050896) 1.223DVL3, WNT5A, ROR2
protein localization (GO:0008104) 2.362WNT5A, DVL1
positive regulation of stress-activated MAPK cascade (GO:0032874) 4.822DVL3, WNT5A
developmental growth (GO:0048589) 4.052WNT5A, DVL1
skeletal system development (GO:0001501) 4.492WNT5A, ROR2
regulation of cell projection organization (GO:0031344) 3.382WNT5A, DVL1
signal transduction by protein phosphorylation (GO:0023014) 3.792WNT5A, ROR2
positive regulation of cell projection organization (GO:0031346) 3.992WNT5A, DVL1
cellular response to stimulus (GO:0051716) 1.972WNT5A, ROR2
somitogenesis (GO:0001756) 5.92WNT5A, ROR2
negative regulation of macromolecule metabolic process (GO:0010605) 2.012WNT5A, DVL1
cellular macromolecule localization (GO:0070727) 3.12WNT5A, DVL1
MAPK cascade (GO:0000165) 3.912WNT5A, ROR2
regulation of neuron differentiation (GO:0045664) 3.392WNT5A, DVL1
positive regulation of neuron differentiation (GO:0045666) 3.982WNT5A, DVL1
positive regulation of molecular function (GO:0044093) 2.232DVL3, WNT5A
macromolecule localization (GO:0033036) 2.342WNT5A, DVL1
regulation of cell proliferation (GO:0042127) 2.412WNT5A, ROR2
developmental process involved in reproduction (GO:0003006) 3.362WNT5A, ROR2
positive regulation of JNK cascade (GO:0046330) 4.982DVL3, WNT5A
regionalization (GO:0003002) 4.242WNT5A, ROR2
regulation of neuron projection development (GO:0010975) 3.692WNT5A, DVL1
neuron projection guidance (GO:0097485) 4.432WNT5A, DVL1
inner ear morphogenesis (GO:0042472) 5.622WNT5A, ROR2
single organism reproductive process (GO:0044702) 2.732WNT5A, ROR2
protein metabolic process (GO:0019538) 1.452WNT5A, ROR2
regulation of MAP kinase activity (GO:0043405) 3.952DVL3, WNT5A
cellular response to stress (GO:0033554) 2.512WNT5A, ROR2
positive regulation of catabolic process (GO:0009896) 3.942WNT5A, DVL1
regulation of catabolic process (GO:0009894) 3.522WNT5A, DVL1
embryonic organ morphogenesis (GO:0048562) 4.922WNT5A, ROR2
negative regulation of metabolic process (GO:0009892) 1.932WNT5A, DVL1
positive regulation of kinase activity (GO:0033674) 3.542DVL3, WNT5A
positive regulation of canonical Wnt signaling pathway (GO:0090263) 4.952DVL1, ROR2
positive regulation of cell migration (GO:0030335) 3.772WNT5A, ROR2
movement of cell or subcellular component (GO:0006928) 2.612WNT5A, DVL1
protein stabilization (GO:0050821) 4.862DVL3, DVL1
positive regulation of protein serine/threonine kinase activity (GO:0071902) 4.062DVL3, WNT5A
regulation of protein serine/threonine kinase activity (GO:0071900) 3.582DVL3, WNT5A
cellular protein metabolic process (GO:0044267) 1.632WNT5A, ROR2
positive regulation of transferase activity (GO:0051347) 3.312DVL3, WNT5A
positive regulation of GTPase activity (GO:0043547) 3.282DVL3, WNT5A
positive regulation of hydrolase activity (GO:0051345) 2.912DVL3, WNT5A
regulation of GTPase activity (GO:0043087) 3.212DVL3, WNT5A
negative regulation of cell proliferation (GO:0008285) 3.262WNT5A, ROR2
synapse assembly (GO:0007416) 5.552WNT5A, DVL1
regulation of biological quality (GO:0065008) 1.682DVL3, DVL1
anatomical structure formation involved in morphogenesis (GO:0048646) 3.012WNT5A, ROR2
positive regulation of cellular component organization (GO:0051130) 2.682WNT5A, DVL1
beta-catenin destruction complex disassembly (GO:1904886) 6.642DVL3, DVL1
positive regulation of protein localization to synapse (GO:1902474) 7.652WNT5A, DVL1
single-organism metabolic process (GO:0044710) 1.632WNT5A, ROR2
tissue development (GO:0009888) 3.272WNT5A, DVL1
positive regulation of MAPK cascade (GO:0043410) 3.572DVL3, WNT5A
macromolecule modification (GO:0043412) 1.732WNT5A, ROR2
protein modification process (GO:0036211) 1.792WNT5A, ROR2
regulation of protein binding (GO:0043393) 4.62WNT5A, DVL1
positive regulation of intracellular signal transduction (GO:1902533) 2.952DVL3, WNT5A
regulation of intracellular signal transduction (GO:1902531) 2.312DVL3, WNT5A
Wnt signaling pathway, calcium modulating pathway (GO:0007223) 6.122WNT5A, ROR2
embryonic digit morphogenesis (GO:0042733) 5.692WNT5A, ROR2
cell fate commitment (GO:0045165) 4.722WNT5A, ROR2
anterior/posterior pattern specification (GO:0009952) 4.712WNT5A, ROR2
regulation of response to stress (GO:0080134) 2.532DVL3, WNT5A
regulation of cellular response to stress (GO:0080135) 3.42DVL3, WNT5A
response to stress (GO:0006950) 1.82WNT5A, ROR2
positive regulation of nervous system development (GO:0051962) 3.642WNT5A, DVL1
regulation of transcription from RNA polymerase II promoter (GO:0006357) 2.242WNT5A, ROR2
regulation of cell motility (GO:2000145) 3.162WNT5A, ROR2
positive regulation of cell motility (GO:2000147) 3.742WNT5A, ROR2
synapse organization (GO:0050808) 4.872WNT5A, DVL1
negative regulation of response to external stimulus (GO:0032102) 4.182WNT5A, DVL1
regulation of response to external stimulus (GO:0032101) 3.062WNT5A, DVL1
phosphorylation (GO:0016310) 2.632WNT5A, ROR2
cell differentiation (GO:0030154) 2.142WNT5A, ROR2
non-canonical Wnt signaling pathway via JNK cascade (GO:0038031) 8.122DVL3, WNT5A
regulation of cellular component organization (GO:0051128) 2.012WNT5A, DVL1
positive regulation of MAP kinase activity (GO:0043406) 4.392DVL3, WNT5A
regulation of protein catabolic process (GO:0042176) 3.832WNT5A, DVL1
cellular component assembly (GO:0022607) 2.142WNT5A, DVL1
axon guidance (GO:0007411) 4.442WNT5A, DVL1
protein complex disassembly (GO:0043241) 4.582DVL3, DVL1
positive regulation of catalytic activity (GO:0043085) 2.42DVL3, WNT5A
regulation of MAPK cascade (GO:0043408) 3.222DVL3, WNT5A
regulation of neurogenesis (GO:0050767) 3.212WNT5A, DVL1
JNK cascade (GO:0007254) 5.742WNT5A, ROR2
positive regulation of multicellular organismal process (GO:0051240) 2.492WNT5A, DVL1
stress-activated protein kinase signaling cascade (GO:0031098) 5.412WNT5A, ROR2
regulation of cell development (GO:0060284) 3.012WNT5A, DVL1
positive regulation of neurogenesis (GO:0050769) 3.772WNT5A, DVL1
macromolecular complex subunit organization (GO:0043933) 2.142DVL3, DVL1
developmental growth involved in morphogenesis (GO:0060560) 5.152WNT5A, DVL1
non-canonical Wnt signaling pathway via MAPK cascade (GO:0038030) 7.942DVL3, WNT5A
regulation of hydrolase activity (GO:0051336) 2.532DVL3, WNT5A
convergent extension (GO:0060026) 7.162WNT5A, DVL1
positive regulation of cell development (GO:0010720) 3.572WNT5A, DVL1
regulation of stress-activated protein kinase signaling cascade (GO:0070302) 4.442DVL3, WNT5A
epithelium development (GO:0060429) 4.572WNT5A, DVL1
positive regulation of stress-activated protein kinase signaling cascade (GO:0070304) 4.822DVL3, WNT5A
regulation of stress-activated MAPK cascade (GO:0032872) 4.452DVL3, WNT5A
regulation of cell differentiation (GO:0045595) 2.422WNT5A, DVL1
regulation of cellular component movement (GO:0051270) 3.082WNT5A, ROR2
axonogenesis (GO:0007409) 4.742WNT5A, DVL1
cell part morphogenesis (GO:0032990) 3.992WNT5A, DVL1
positive regulation of developmental process (GO:0051094) 2.772WNT5A, DVL1
regulation of binding (GO:0051098) 4.082WNT5A, DVL1
positive regulation of cell differentiation (GO:0045597) 3.012WNT5A, DVL1
system development (GO:0048731) 2.922WNT5A, ROR2
positive regulation of protein kinase activity (GO:0045860) 3.612DVL3, WNT5A
regulation of protein stability (GO:0031647) 4.332DVL3, DVL1
convergent extension involved in organogenesis (GO:0060029) 8.122WNT5A, DVL1
cell projection organization (GO:0030030) 3.142WNT5A, DVL1
negative regulation of cellular metabolic process (GO:0031324) 2.012WNT5A, DVL1
regulation of JNK cascade (GO:0046328) 4.652DVL3, WNT5A
regulation of JUN kinase activity (GO:0043506) 5.332DVL3, WNT5A
positive regulation of JUN kinase activity (GO:0043507) 5.592DVL3, WNT5A
segmentation (GO:0035282) 5.82WNT5A, ROR2
pattern specification process (GO:0007389) 3.792WNT5A, ROR2
macromolecular complex disassembly (GO:0032984) 4.532DVL3, DVL1
growth (GO:0040007) 3.82WNT5A, DVL1
protein complex subunit organization (GO:0071822) 2.62DVL3, DVL1
positive regulation of protein catabolic process (GO:0045732) 4.182WNT5A, DVL1
cellular component morphogenesis (GO:0032989) 3.52WNT5A, DVL1
neuron projection morphogenesis (GO:0048812) 4.342WNT5A, DVL1
tissue morphogenesis (GO:0048729) 3.872WNT5A, DVL1
protein phosphorylation (GO:0006468) 2.892WNT5A, ROR2
regulation of cell migration (GO:0030334) 3.232WNT5A, ROR2
neural tube development (GO:0021915) 5.92WNT5A, DVL1
morphogenesis of an epithelium (GO:0002009) 4.082WNT5A, DVL1
cellular protein localization (GO:0034613) 3.112WNT5A, DVL1
regulation of protein localization to synapse (GO:1902473) 7.532WNT5A, DVL1
cellular protein modification process (GO:0006464) 1.792WNT5A, ROR2
reproductive process (GO:0022414) 2.552WNT5A, ROR2
stress-activated MAPK cascade (GO:0051403) 5.452WNT5A, ROR2
cellular component disassembly (GO:0022411) 3.522DVL3, DVL1
response to chemical (GO:0042221) 1.982DVL3, WNT5A
tube development (GO:0035295) 4.412WNT5A, DVL1
localization (GO:0051179) 1.42WNT5A, DVL1
cellular localization (GO:0051641) 2.322WNT5A, DVL1
positive regulation of cellular component movement (GO:0051272) 3.712WNT5A, ROR2
regulation of locomotion (GO:0040012) 3.122WNT5A, ROR2
cell projection morphogenesis (GO:0048858) 4.052WNT5A, DVL1
positive regulation of locomotion (GO:0040017) 3.712WNT5A, ROR2
phosphate-containing compound metabolic process (GO:0006796) 2.162WNT5A, ROR2
phosphorus metabolic process (GO:0006793) 2.152WNT5A, ROR2
positive regulation of neuron projection development (GO:0010976) 4.262WNT5A, DVL1

NET-GE enrichment

Term New enriched termICP valueGenes
regulation of apoptotic signaling pathway (GO:2001233) NEW3.830.019DVL1, DVL3, WNT5A, ROR2
positive regulation of response to stimulus (GO:0048584) -2.180.045DVL1, DVL3, WNT5A, ROR2
negative regulation of epithelial cell proliferation (GO:0050680) NEW4.980.034WNT5A, DVL1, ROR2
regulation of Wnt signaling pathway (GO:0030111) -3.980.003DVL1, DVL3, WNT5A, ROR2
establishment or maintenance of cell polarity (GO:0007163) NEW5.00.033DVL1, DVL3, WNT5A
hair cycle phase (GO:0044851) NEW9.040.023DVL3, DVL1
signal transduction by phosphorylation (GO:0023014) -3.790.001DVL1, DVL3, WNT5A, ROR2
positive regulation of signal transduction (GO:0009967) -2.50.007DVL1, DVL3, WNT5A, ROR2
cornea development in camera-type eye (GO:0061303) NEW7.650.007WNT5A, ROR2
MAPK cascade (GO:0000165) -3.910.001DVL1, DVL3, WNT5A, ROR2
epithelial cell differentiation (GO:0030855) NEW3.980.011DVL1, DVL3, WNT5A, ROR2
regulation of striated muscle tissue development (GO:0016202) NEW5.090.045DVL1, DVL3, WNT5A
protein import into nucleus (GO:0006606) NEW5.240.004DVL1, DVL3, WNT5A
regionalization (GO:0003002) -4.240.006DVL1, DVL3, WNT5A, ROR2
regulation of embryonic development (GO:0045995) -4.980.0DVL1, DVL3, WNT5A, ROR2
somitogenesis (GO:0001756) -5.90.02WNT5A, ROR2
non-canonical Wnt signaling pathway (GO:0035567) -4.790.0DVL1, DVL3, WNT5A, ROR2
regulation of establishment of planar polarity (GO:0090175) -5.020.0DVL1, DVL3, WNT5A, ROR2
planar cell polarity pathway involved in neural tube closure (GO:0090179) -7.160.0DVL1, DVL3, WNT5A
Wnt signaling pathway (GO:0016055) -3.880.0DVL1, DVL3, WNT5A, ROR2
response to nutrient levels (GO:0031667) NEW3.770.012DVL1, DVL3, WNT5A, ROR2
optic cup formation involved in camera-type eye development (GO:0003408) NEW8.630.0WNT5A, ROR2
regulation of canonical Wnt signaling pathway (GO:0060828) -4.260.001DVL1, DVL3, WNT5A, ROR2
regulation of cell morphogenesis (GO:0022604) NEW3.40.047DVL1, DVL3, WNT5A, ROR2
embryonic morphogenesis (GO:0048598) -3.720.038DVL1, DVL3, WNT5A, ROR2
regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) -7.020.0DVL1, DVL3, WNT5A
regulation of anatomical structure morphogenesis (GO:0022603) -2.790.002DVL1, DVL3, WNT5A, ROR2
positive regulation of canonical Wnt signaling pathway (GO:0090263) -4.950.041WNT5A, DVL1, ROR2
positive regulation of Wnt signaling pathway (GO:0030177) -4.70.0DVL1, DVL3, WNT5A, ROR2
positive regulation of gene expression (GO:0010628) -2.350.016DVL1, DVL3, WNT5A, ROR2
embryonic axis specification (GO:0000578) NEW6.360.0WNT5A, DVL1, ROR2
uterus development (GO:0060065) NEW7.020.019WNT5A, ROR2
negative regulation of Wnt signaling pathway (GO:0030178) -4.440.0DVL1, DVL3, WNT5A, ROR2
cochlea morphogenesis (GO:0090103) -6.640.0DVL1, DVL3, WNT5A
negative regulation of phosphate metabolic process (GO:0045936) NEW3.450.024DVL1, DVL3, WNT5A, ROR2
gonad development (GO:0008406) NEW4.920.04DVL1, DVL3, WNT5A
neural tube closure (GO:0001843) NEW5.380.008DVL1, DVL3, WNT5A
regulation of muscle tissue development (GO:1901861) NEW5.070.046DVL1, DVL3, WNT5A
embryonic pattern specification (GO:0009880) NEW5.80.002WNT5A, DVL1, ROR2
regulation of cardiac muscle tissue development (GO:0055024) NEW5.860.003DVL1, DVL3, WNT5A
tube closure (GO:0060606) NEW5.360.009DVL1, DVL3, WNT5A
canonical Wnt signaling pathway (GO:0060070) -5.260.0DVL1, DVL3, WNT5A
Wnt signaling pathway, calcium modulating pathway (GO:0007223) -6.120.001WNT5A, ROR2
Wnt signaling pathway, planar cell polarity pathway (GO:0060071) -5.120.0DVL1, DVL3, WNT5A, ROR2
regulation of cellular response to stress (GO:0080135) -3.40.028DVL1, DVL3, WNT5A, ROR2
positive regulation of protein catabolic process (GO:0045732) -4.180.026DVL1, DVL3, WNT5A
positive regulation of nucleocytoplasmic transport (GO:0046824) NEW4.930.02DVL1, DVL3, WNT5A
positive regulation of cell motility (GO:2000147) -3.740.009DVL1, DVL3, WNT5A, ROR2
negative regulation of phosphorus metabolic process (GO:0010563) NEW3.450.024DVL1, DVL3, WNT5A, ROR2
regulation of muscle organ development (GO:0048634) NEW5.070.049DVL1, DVL3, WNT5A
tube formation (GO:0035148) NEW4.980.0DVL1, DVL3, WNT5A, ROR2
positive regulation of signaling (GO:0023056) -2.410.009DVL1, DVL3, WNT5A, ROR2
axis specification (GO:0009798) NEW5.420.009WNT5A, DVL1, ROR2
positive regulation of cell communication (GO:0010647) -2.410.009DVL1, DVL3, WNT5A, ROR2
anatomical structure morphogenesis (GO:0009653) -2.530.016DVL1, DVL3, WNT5A, ROR2
convergent extension involved in organogenesis (GO:0060029) -8.120.0WNT5A, DVL1
negative regulation of cellular response to growth factor stimulus (GO:0090288) NEW4.920.016DVL1, DVL3, WNT5A
non-canonical Wnt signaling pathway via MAPK cascade (GO:0038030) -7.940.002DVL3, WNT5A
non-canonical Wnt signaling pathway via JNK cascade (GO:0038031) -8.120.0DVL3, WNT5A
reproductive structure development (GO:0048608) NEW4.080.009DVL1, DVL3, WNT5A, ROR2
single-organism nuclear import (GO:1902593) NEW5.240.004DVL1, DVL3, WNT5A
protein import (GO:0017038) NEW4.850.012DVL1, DVL3, WNT5A
cellular response to hormone stimulus (GO:0032870) NEW3.990.044DVL1, DVL3, WNT5A, ROR2
positive regulation of transcription, DNA-templated (GO:0045893) -2.560.011DVL1, DVL3, WNT5A, ROR2
positive regulation of biosynthetic process (GO:0009891) -2.290.029DVL1, DVL3, WNT5A, ROR2
regulation of epithelial cell proliferation (GO:0050678) NEW4.060.008DVL1, DVL3, WNT5A, ROR2
positive regulation of RNA metabolic process (GO:0051254) -2.510.014DVL1, DVL3, WNT5A, ROR2
positive regulation of RNA biosynthetic process (GO:1902680) -2.540.013DVL1, DVL3, WNT5A, ROR2
response to extracellular stimulus (GO:0009991) NEW3.710.017DVL1, DVL3, WNT5A, ROR2
positive regulation of cellular biosynthetic process (GO:0031328) -2.30.028DVL1, DVL3, WNT5A, ROR2
convergent extension (GO:0060026) -7.160.0DVL1, DVL3, WNT5A
left/right pattern formation (GO:0060972) NEW7.530.014DVL3, DVL1
regulation of muscle cell differentiation (GO:0051147) NEW4.680.035DVL1, DVL3, WNT5A
nephron tubule formation (GO:0072079) NEW7.160.008WNT5A, ROR2
prepulse inhibition (GO:0060134) NEW7.240.01DVL3, DVL1
positive regulation of JUN kinase activity (GO:0043507) -5.590.045DVL3, WNT5A
segmentation (GO:0035282) -5.80.023WNT5A, ROR2
pattern specification process (GO:0007389) -3.790.033DVL1, DVL3, WNT5A, ROR2
positive regulation of macromolecule biosynthetic process (GO:0010557) -2.390.021DVL1, DVL3, WNT5A, ROR2
tissue morphogenesis (GO:0048729) -3.870.02DVL1, DVL3, WNT5A, ROR2
forebrain development (GO:0030900) NEW5.480.005DVL1, DVL3, WNT5A
negative regulation of canonical Wnt signaling pathway (GO:0090090) -4.630.0DVL1, DVL3, WNT5A, ROR2
positive regulation of cell migration (GO:0030335) -3.770.008DVL1, DVL3, WNT5A, ROR2
epithelium development (GO:0060429) -4.570.008DVL1, DVL3, WNT5A, ROR2
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) -2.350.022DVL1, DVL3, WNT5A, ROR2
neuron differentiation (GO:0030182) NEW4.170.006DVL1, DVL3, WNT5A, ROR2
morphogenesis of an epithelium (GO:0002009) -4.080.01DVL1, DVL3, WNT5A, ROR2
nuclear import (GO:0051170) NEW5.060.004DVL1, DVL3, WNT5A
positive regulation of nitrogen compound metabolic process (GO:0051173) -2.290.024DVL1, DVL3, WNT5A, ROR2
positive regulation of cellular component movement (GO:0051272) -3.710.01DVL1, DVL3, WNT5A, ROR2
inner ear morphogenesis (GO:0042472) -5.620.0DVL1, DVL3, WNT5A, ROR2
positive regulation of locomotion (GO:0040017) -3.710.013DVL1, DVL3, WNT5A, ROR2
regulation of multicellular organismal development (GO:2000026) -2.310.019DVL1, DVL3, WNT5A, ROR2
regulation of organ morphogenesis (GO:2000027) -4.220.0DVL1, DVL3, WNT5A, ROR2
response to acid chemical (GO:0001101) NEW4.050.012DVL1, DVL3, WNT5A, ROR2
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
intracellular organelle part (GO:0044446) 0.814DVL1, DVL3, WNT5A, ROR2
intracellular part (GO:0044424) 0.284DVL1, DVL3, WNT5A, ROR2
cytoplasmic part (GO:0044444) 0.824DVL1, DVL3, WNT5A, ROR2
cell part (GO:0044464) 0.114DVL1, DVL3, WNT5A, ROR2
organelle part (GO:0044422) 0.794DVL1, DVL3, WNT5A, ROR2
cytoplasm (GO:0005737) 1.013DVL1, DVL3, WNT5A
membrane part (GO:0044425) 0.953WNT5A, DVL1, ROR2
membrane (GO:0016020) 0.683WNT5A, DVL1, ROR2
plasma membrane (GO:0005886) 1.393WNT5A, DVL1, ROR2
membrane-bounded organelle (GO:0043227) 0.472WNT5A, DVL1
organelle (GO:0043226) 0.42WNT5A, DVL1
intrinsic component of membrane (GO:0031224) 1.132WNT5A, ROR2
clathrin-coated vesicle membrane (GO:0030665) 5.62WNT5A, ROR2
endocytic vesicle membrane (GO:0030666) 4.822WNT5A, ROR2
vesicle (GO:0031982) 1.642WNT5A, DVL1
coated vesicle membrane (GO:0030662) 5.02WNT5A, ROR2
integral component of membrane (GO:0016021) 1.142WNT5A, ROR2
clathrin-coated endocytic vesicle membrane (GO:0030669) 6.092WNT5A, ROR2
membrane-bounded vesicle (GO:0031988) 1.712WNT5A, DVL1
cytoplasmic vesicle part (GO:0044433) 3.412WNT5A, ROR2
plasma membrane part (GO:0044459) 1.952DVL1, ROR2
bounding membrane of organelle (GO:0098588) 2.392WNT5A, ROR2
cytoplasmic vesicle membrane (GO:0030659) 3.672WNT5A, ROR2
vesicle membrane (GO:0012506) 3.632WNT5A, ROR2
organelle membrane (GO:0031090) 1.972WNT5A, ROR2
protein complex (GO:0043234) 1.512DVL3, DVL1
Wnt signalosome (GO:1990909) 7.42DVL3, DVL1
macromolecular complex (GO:0032991) 1.352DVL3, DVL1
cytosol (GO:0005829) 1.682DVL3, DVL1
intracellular (GO:0005622) 2.372DVL1, ROR2
whole membrane (GO:0098805) 2.852WNT5A, ROR2

NET-GE enrichment

Term New enriched termICP valueGenes
clathrin-coated vesicle membrane (GO:0030665) -5.60.005WNT5A, ROR2
receptor complex (GO:0043235) NEW4.010.036DVL1, DVL3, WNT5A
endocytic vesicle membrane (GO:0030666) -4.820.037WNT5A, ROR2
lateral plasma membrane (GO:0016328) NEW5.890.016DVL3, DVL1
coated vesicle membrane (GO:0030662) -5.00.024WNT5A, ROR2
organelle lumen (GO:0043233) NEW3.050.015DVL1, DVL3, WNT5A, ROR2
apicolateral plasma membrane (GO:0016327) NEW7.030.001DVL3, DVL1
clathrin-coated endocytic vesicle membrane (GO:0030669) -6.090.002WNT5A, ROR2
membrane-enclosed lumen (GO:0031974) NEW3.050.02DVL1, DVL3, WNT5A, ROR2
intracellular organelle lumen (GO:0070013) NEW3.050.011DVL1, DVL3, WNT5A, ROR2
cell cortex (GO:0005938) NEW4.780.014DVL3, DVL1