Disease ID | Disease name | Source of annotation with ALDH2 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
610251 | ALCOHOL SENSITIVITY, ACUTE | OMIM | link to OMIM | 1 | ALDH2 |
103780 | ALCOHOL DEPENDENCE | ClinVar | link to OMIM | 7 | ADH1C, RCBTB1, ADH1B, GABRA2, HTR2A, ALDH2, TAS2R16 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Lysine degradation | hsa00310 | 7.01 |
Glycerolipid metabolism | hsa00561 | 6.91 |
Tryptophan metabolism | hsa00380 | 7.34 |
Arginine and proline metabolism | hsa00330 | 6.84 |
Pyruvate metabolism | hsa00620 | 7.45 |
beta-Alanine metabolism | hsa00410 | 7.72 |
Fatty acid degradation | hsa00071 | 7.15 |
Valine, leucine and isoleucine degradation | hsa00280 | 7.09 |
Ascorbate and aldarate metabolism | hsa00053 | 8.07 |
Pentose and glucuronate interconversions | hsa00040 | 7.68 |
Glycolysis / Gluconeogenesis | hsa00010 | 6.64 |
Metabolic pathways | hsa01100 | 2.49 |
Histidine metabolism | hsa00340 | 8.24 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Serotonin clearance from the synaptic cleft | R-HSA-380615 | 11.98 |
Metabolism of serotonin | R-HSA-380612 | 11.98 |
Ethanol oxidation | R-HSA-71384 | 9.66 |
Biological oxidations | R-HSA-211859 | 5.55 |
Phase 1 - Functionalization of compounds | R-HSA-211945 | 6.7 |
Metabolism | R-HSA-1430728 | 2.34 |
Neuronal System | R-HSA-112316 | 4.82 |
Transmission across Chemical Synapses | R-HSA-112315 | 5.28 |
Neurotransmitter Clearance In The Synaptic Cleft | R-HSA-112311 | 9.98 |
GO term | GO ID | GO IC |
---|---|---|
GO:0004030 | 7.79 | |
GO:0004029 | 6.74 | |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | GO:0016620 | 6.13 |
catalytic activity | GO:0003824 | 1.05 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors | GO:0016903 | 5.87 |
electron carrier activity | GO:0009055 | 4.97 |
oxidoreductase activity | GO:0016491 | 3.12 |