Disease ID | Disease name | Source of annotation with HTR2A | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
164230 | OBSESSIVE-COMPULSIVE DISORDER | OMIM | link to OMIM | 3 | BDNF, SLC6A4, HTR2A |
606788 | ANOREXIA NERVOSA, SUSCEPTIBILITY TO, 1 | OMIM | link to OMIM | 1 | HTR2A |
181500 | SCHIZOPHRENIA | OMIM | link to OMIM | 17 | COMT, DISC2, MTHFR, DISC1, CHI3L1, SYN2, MC4R, DAO, AKT1, HTR2A, APOL2, DTNBP1, SETD1A, DRD3, APOL4, RTN4R, DAOA |
608516 | MAJOR DEPRESSIVE DISORDER | OMIM | link to OMIM | 4 | FKBP5, TPH2, APOE, HTR2A |
103780 | ALCOHOL DEPENDENCE | OMIM | link to OMIM | 7 | ADH1C, RCBTB1, ADH1B, GABRA2, HTR2A, ALDH2, TAS2R16 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Inflammatory mediator regulation of TRP channels | hsa04750 | 6.07 |
Calcium signaling pathway | hsa04020 | 5.22 |
Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
Gap junction | hsa04540 | 6.24 |
Serotonergic synapse | hsa04726 | 5.84 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Amine ligand-binding receptors | R-HSA-375280 | 7.59 |
Signaling by GPCR | R-HSA-372790 | 2.68 |
GPCR downstream signaling | R-HSA-388396 | 3.07 |
Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.26 |
G alpha (q) signalling events | R-HSA-416476 | 5.42 |
GPCR ligand binding | R-HSA-500792 | 4.19 |
Serotonin receptors | R-HSA-390666 | 9.4 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
signaling receptor activity | GO:0038023 | 2.49 |
drug binding | GO:0008144 | 5.03 |
molecular transducer activity | GO:0060089 | 2.32 |
macromolecular complex binding | GO:0044877 | 2.61 |
binding | GO:0005488 | 0.18 |
signal transducer activity | GO:0004871 | 2.28 |
heterocyclic compound binding | GO:1901363 | 1.06 |
G-protein coupled receptor activity | GO:0004930 | 2.95 |
serotonin receptor activity | GO:0099589 | 6.85 |
G-protein alpha-subunit binding | GO:0001965 | 6.6 |
protein complex binding | GO:0032403 | 3.09 |
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding | GO:0071886 | 9.05 |
G-protein coupled serotonin receptor activity | GO:0004993 | 6.91 |
G-protein coupled amine receptor activity | GO:0008227 | 5.83 |
serotonin binding | GO:0051378 | 7.54 |
amine binding | GO:0043176 | 7.34 |
virus receptor activity | GO:0001618 | 5.49 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
protein binding | GO:0005515 | 0.46 |
organic cyclic compound binding | GO:0097159 | 1.05 |
transmembrane receptor activity | GO:0099600 | 2.53 |
receptor activity | GO:0004872 | 2.32 |