Disease ID | Disease name | Source of annotation with ADH1C | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS168600 | PARKINSON DISEASE | OMIM | link to OMIM | 30 | ATP13A2, FGF20, VPS13C, DNAJC13, ATXN2, PINK1, CHCHD2, ADH1C, UCHL1, GIGYF2, SYNJ1, PODXL, HTRA2, LRRK2, TBP, PARK2, ATXN8OS, SNCAIP, GBA, SNCA, NR4A2, PLA2G6, GLUD2, PARK7, ATXN3, MAPT, DNAJC6, EIF4G1, FBXO7, VPS35 |
103780 | ALCOHOL DEPENDENCE | ClinVar, OMIM | link to OMIM | 7 | ADH1C, RCBTB1, ADH1B, GABRA2, HTR2A, ALDH2, TAS2R16 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Metabolism of xenobiotics by cytochrome P450 | hsa00980 | 6.48 |
Drug metabolism - cytochrome P450 | hsa00982 | 6.6 |
Retinol metabolism | hsa00830 | 6.79 |
Metabolic pathways | hsa01100 | 2.49 |
Fatty acid degradation | hsa00071 | 7.15 |
Chemical carcinogenesis | hsa05204 | 6.36 |
Glycolysis / Gluconeogenesis | hsa00010 | 6.64 |
Tyrosine metabolism | hsa00350 | 7.64 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
RA biosynthesis pathway | R-HSA-5365859 | 8.59 |
Ethanol oxidation | R-HSA-71384 | 9.66 |
Biological oxidations | R-HSA-211859 | 5.55 |
Phase 1 - Functionalization of compounds | R-HSA-211945 | 6.7 |
Metabolism | R-HSA-1430728 | 2.34 |
Signal Transduction | R-HSA-162582 | 1.78 |
Signaling by Retinoic Acid | R-HSA-5362517 | 7.62 |
GO term | GO ID | GO IC |
---|---|---|
cation binding | GO:0043169 | 1.4 |
metal ion binding | GO:0046872 | 1.41 |
oxidoreductase activity, acting on CH-OH group of donors | GO:0016614 | 4.83 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | GO:0016616 | 5.0 |
transition metal ion binding | GO:0046914 | 2.48 |
GO:0004024 | 7.95 | |
GO:0004022 | 7.66 | |
ion binding | GO:0043167 | 1.36 |
catalytic activity | GO:0003824 | 1.05 |
binding | GO:0005488 | 0.18 |
oxidoreductase activity | GO:0016491 | 3.12 |
retinol dehydrogenase activity | GO:0004745 | 6.85 |
zinc ion binding | GO:0008270 | 2.66 |