Gene table of B2M : beta-2-microglobulin

Gene-disease associations table

Disease IDDisease nameSource of annotation with B2MOMIM linkNumber of associated genesgenes
105200AMYLOIDOSIS, FAMILIAL VISCERALOMIM link to OMIM 4APOA1, B2M, FGA, LYZ
241600IMMUNODEFICIENCY 43ClinVar, OMIM, HUMSAVAR link to OMIM 1B2M

Download the gene annotation in CSV format

Annotation of the gene B2M

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Antigen processing and presentationhsa046126.04
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Immune SystemR-HSA-1682562.37
Cytokine Signaling in Immune systemR-HSA-12802153.74
HIV InfectionR-HSA-1629065.22
The role of Nef in HIV-1 replication and disease pathogenesisR-HSA-1649528.18
Antigen Presentation: Folding, assembly and peptide loading of class I MHCR-HSA-9831706.64
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adaptersR-HSA-1649388.59
Adaptive Immune SystemR-HSA-12802183.19
DiseaseR-HSA-16436853.33
Host Interactions of HIV factorsR-HSA-1629095.99
Antigen processing-Cross presentationR-HSA-12369755.88
ER-Phagosome pathwayR-HSA-12369746.08
Endosomal/Vacuolar pathwayR-HSA-12369776.92
Interferon gamma signalingR-HSA-8773005.67
AmyloidsR-HSA-9772257.37
Interferon SignalingR-HSA-9135314.95
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellR-HSA-1989334.7
Infectious diseaseR-HSA-56632054.47
Innate Immune SystemR-HSA-1682493.17
Class I MHC mediated antigen processing & presentationR-HSA-9831694.65
DAP12 signalingR-HSA-24244914.64
Nef mediated downregulation of MHC class I complex cell surface expressionR-HSA-1649409.66
DAP12 interactionsR-HSA-21721274.56
Associated GO terms for Molecular function
GO termGO IDGO IC
carbohydrate derivative bindingGO:00973672.03
glycoprotein bindingGO:00019485.11
identical protein bindingGO:00428022.63
bindingGO:00054880.18
protein bindingGO:00055150.46