Gene table of CLP1 : cleavage and polyadenylation factor I subunit 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CLP1	OMIM link	Number of associated genes	genes
PS607596	PONTOCEREBELLAR HYPOPLASIA	ClinVar, OMIM, HUMSAVAR	link to OMIM	13	AMPD2, EXOSC3, CLP1, SEPSECS, TSEN34, TSEN2, PCLO, VPS53, TSEN54, KCNT1, RARS2, VRK1, CHMP1A

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
mRNA surveillance pathway	hsa03015	6.28

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
mRNA Splicing - Major Pathway	R-HSA-72163	6.15
mRNA Splicing	R-HSA-72172	6.15
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	8.46
Gene Expression	R-HSA-74160	2.72
Cleavage of Growing Transcript in the Termination Region	R-HSA-109688	7.56
mRNA 3'-end processing	R-HSA-72187	7.89
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	6.1
Processing of Intronless Pre-mRNAs	R-HSA-77595	9.18
RNA Polymerase II Transcription Termination	R-HSA-73856	7.56
RNA Polymerase II Transcription	R-HSA-73857	6.25

Associated GO terms for Molecular function

GO term	GO ID	GO IC
nucleobase-containing compound kinase activity	GO:0019205	5.85
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
polyribonucleotide kinase activity	GO:0051732	9.74
polydeoxyribonucleotide kinase activity	GO:0051733	8.64
polynucleotide 5'-hydroxyl-kinase activity	GO:0051731	8.35
ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	GO:0051736	9.74
ATP-dependent polynucleotide kinase activity	GO:0051734	8.64
nucleotide binding	GO:0000166	1.96
transferase activity	GO:0016740	1.95
nucleoside phosphate binding	GO:1901265	1.96
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
ATP binding	GO:0005524	2.43
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	GO:0046404	8.64
kinase activity	GO:0016301	2.93
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
adenyl ribonucleotide binding	GO:0032559	2.41
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19