Gene table of TSEN34 : tRNA splicing endonuclease subunit 34

Gene-disease associations table

Disease ID	Disease name	Source of annotation with TSEN34	OMIM link	Number of associated genes	genes
PS607596	PONTOCEREBELLAR HYPOPLASIA	ClinVar, OMIM, HUMSAVAR	link to OMIM	13	AMPD2, EXOSC3, CLP1, SEPSECS, TSEN34, TSEN2, PCLO, VPS53, TSEN54, KCNT1, RARS2, VRK1, CHMP1A

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
tRNA-intron endonuclease activity	GO:0000213	8.35
hydrolase activity	GO:0016787	1.9
tRNA-specific ribonuclease activity	GO:0004549	6.97
nucleic acid binding	GO:0003676	1.44
nuclease activity	GO:0004518	4.33
organic cyclic compound binding	GO:0097159	1.05
lyase activity	GO:0016829	4.53
ribonuclease activity	GO:0004540	5.04
endoribonuclease activity	GO:0004521	5.58
hydrolase activity, acting on ester bonds	GO:0016788	3.1
endoribonuclease activity, producing 3'-phosphomonoesters	GO:0016892	7.34
catalytic activity	GO:0003824	1.05
binding	GO:0005488	0.18
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	GO:0016894	6.74
endonuclease activity	GO:0004519	4.78
heterocyclic compound binding	GO:1901363	1.06