| Disease ID | Disease name | Source of annotation with CXCR4 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 193670 | WHIM SYNDROME | ClinVar, OMIM | link to OMIM | 1 | CXCR4 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Pathways in cancer | hsa05200 | 3.98 |
| Intestinal immune network for IgA production | hsa04672 | 6.79 |
| Leukocyte transendothelial migration | hsa04670 | 5.74 |
| Endocytosis | hsa04144 | 4.92 |
| Axon guidance | hsa04360 | 5.63 |
| Chemokine signaling pathway | hsa04062 | 5.19 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| Binding and entry of HIV virion | R-HSA-173107 | 10.98 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| G alpha (i) signalling events | R-HSA-418594 | 5.1 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
| HIV Infection | R-HSA-162906 | 5.22 |
| Peptide ligand-binding receptors | R-HSA-375276 | 5.41 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 7.2 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 9.4 |
| Disease | R-HSA-1643685 | 3.33 |
| HIV Life Cycle | R-HSA-162587 | 5.89 |
| GO term | GO ID | GO IC |
|---|---|---|
| myosin light chain binding | GO:0032027 | 7.95 |
| ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
| ubiquitin-like protein binding | GO:0032182 | 4.93 |
| cytokine binding | GO:0019955 | 5.21 |
| enzyme binding | GO:0019899 | 2.27 |
| drug binding | GO:0008144 | 5.03 |
| chemokine receptor activity | GO:0004950 | 6.52 |
| molecular transducer activity | GO:0060089 | 2.32 |
| receptor activity | GO:0004872 | 2.32 |
| signal transducer activity | GO:0004871 | 2.28 |
| signaling receptor activity | GO:0038023 | 2.49 |
| C-X-C chemokine receptor activity | GO:0016494 | 7.79 |
| G-protein coupled peptide receptor activity | GO:0008528 | 4.86 |
| G-protein coupled receptor activity | GO:0004930 | 2.95 |
| actin binding | GO:0003779 | 3.74 |
| coreceptor activity | GO:0015026 | 6.1 |
| cytokine receptor activity | GO:0004896 | 5.24 |
| peptide receptor activity | GO:0001653 | 4.84 |
| myosin binding | GO:0017022 | 5.66 |
| ubiquitin protein ligase binding | GO:0031625 | 4.17 |
| G-protein coupled chemoattractant receptor activity | GO:0001637 | 6.52 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| virus receptor activity | GO:0001618 | 5.49 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| ubiquitin binding | GO:0043130 | 5.09 |
| protein binding | GO:0005515 | 0.46 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| binding | GO:0005488 | 0.18 |