Gene table of HRG : histidine rich glycoprotein

Gene-disease associations table

Disease ID	Disease name	Source of annotation with HRG	OMIM link	Number of associated genes	genes
PS188050	THROMBOPHILIA	ClinVar, OMIM, HUMSAVAR	link to OMIM	13	HRG, SERPIND1, F5, MTHFR, SERPINC1, THBD, F2, PROS1, PLAT, F9, HABP2, F13A1, PROC

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Platelet activation, signaling and aggregation	R-HSA-76002	5.15
Dissolution of Fibrin Clot	R-HSA-75205	9.28
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	6.59
Platelet degranulation	R-HSA-114608	6.68
Hemostasis	R-HSA-109582	3.98

Associated GO terms for Molecular function

GO term	GO ID	GO IC
peptidase inhibitor activity	GO:0030414	4.55
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
enzyme inhibitor activity	GO:0004857	3.78
molecular function regulator	GO:0098772	2.51
heterocyclic compound binding	GO:1901363	1.06
sulfur compound binding	GO:1901681	4.32
cation binding	GO:0043169	1.4
transition metal ion binding	GO:0046914	2.48
ion binding	GO:0043167	1.36
protein complex binding	GO:0032403	3.09
metal ion binding	GO:0046872	1.41
endopeptidase regulator activity	GO:0061135	4.57
glycoprotein binding	GO:0001948	5.11
heme binding	GO:0020037	4.86
enzyme regulator activity	GO:0030234	2.85
peptidase regulator activity	GO:0061134	4.37
heparan sulfate proteoglycan binding	GO:0043395	6.85
proteoglycan binding	GO:0043394	6.34
endopeptidase inhibitor activity	GO:0004866	4.6
serine-type endopeptidase inhibitor activity	GO:0004867	5.16
cysteine-type endopeptidase inhibitor activity	GO:0004869	5.71
heparin binding	GO:0008201	4.68
tetrapyrrole binding	GO:0046906	4.8
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
immunoglobulin binding	GO:0019865	6.6
glycosaminoglycan binding	GO:0005539	4.42
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43
zinc ion binding	GO:0008270	2.66