Disease ID | Disease name | Source of annotation with MMP2 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
259600 | MULTICENTRIC OSTEOLYSIS, NODULOSIS, AND ARTHROPATHY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | MMP2 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Bladder cancer | hsa05219 | 7.38 |
Proteoglycans in cancer | hsa05205 | 5.02 |
Pathways in cancer | hsa05200 | 3.98 |
GnRH signaling pathway | hsa04912 | 6.18 |
Leukocyte transendothelial migration | hsa04670 | 5.74 |
Estrogen signaling pathway | hsa04915 | 6.11 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 8.59 |
EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 7.34 |
Degradation of the extracellular matrix | R-HSA-1474228 | 6.11 |
Metabolism of proteins | R-HSA-392499 | 3.41 |
Collagen degradation | R-HSA-1442490 | 7.03 |
Activation of Matrix Metalloproteinases | R-HSA-1592389 | 8.03 |
Extracellular matrix organization | R-HSA-1474244 | 4.91 |
Axon guidance | R-HSA-422475 | 3.93 |
EPH-Ephrin signaling | R-HSA-2682334 | 6.43 |
Developmental Biology | R-HSA-1266738 | 3.48 |
GO term | GO ID | GO IC |
---|---|---|
hydrolase activity | GO:0016787 | 1.9 |
endopeptidase activity | GO:0004175 | 3.63 |
metalloendopeptidase activity | GO:0004222 | 5.02 |
transition metal ion binding | GO:0046914 | 2.48 |
serine hydrolase activity | GO:0017171 | 4.26 |
metal ion binding | GO:0046872 | 1.41 |
cation binding | GO:0043169 | 1.4 |
ion binding | GO:0043167 | 1.36 |
catalytic activity | GO:0003824 | 1.05 |
peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
zinc ion binding | GO:0008270 | 2.66 |
protein binding | GO:0005515 | 0.46 |
serine-type endopeptidase activity | GO:0004252 | 4.4 |
peptidase activity | GO:0008233 | 3.23 |
serine-type peptidase activity | GO:0008236 | 4.27 |
metallopeptidase activity | GO:0008237 | 4.5 |
binding | GO:0005488 | 0.18 |