Gene table of PRDM16 : PR/SET domain 16

Gene-disease associations table

Disease IDDisease nameSource of annotation with PRDM16OMIM linkNumber of associated genesgenes
PS115200DILATED CARDIOMYOPATHYClinVar, OMIM, HUMSAVAR link to OMIM 36MYBPC3, VCL, PSEN2, PLN, LDB3, ACTC1, BAG3, RBM20, CSRP3, RAF1, MYH7, SGCD, TTN, FKTN, CRYAB, NEXN, SDHA, ABCC9, DSG2, ACTN2, TNNT2, GATAD1, EYA4, TNNC1, LAMA4, SCN5A, MYH6, DMD, TPM1, TNNI3, PRDM16, DES, LMNA, TMPO, MYPN, PSEN1
PS604169LEFT VENTRICULAR NONCOMPACTIONClinVar, OMIM, HUMSAVAR link to OMIM 9TPM1, PRDM16, LDB3, MYH7, TNNT2, MYBPC3, ACTC1, DTNA, MIB1

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Annotation of the gene PRDM16

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Chromatin organizationR-HSA-48397265.19
PKMTs methylate histone lysinesR-HSA-32148417.66
Chromatin modifying enzymesR-HSA-32475095.19
Associated GO terms for Molecular function
GO termGO IDGO IC
histone-lysine N-methyltransferase activityGO:00180245.93
histone methyltransferase activityGO:00420545.68
activating transcription factor bindingGO:00336135.68
lysine N-methyltransferase activityGO:00162785.7
protein-lysine N-methyltransferase activityGO:00162795.71
protein methyltransferase activityGO:00082765.33
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
methyltransferase activityGO:00081684.35
heterocyclic compound bindingGO:19013631.06
sequence-specific DNA bindingGO:00435652.79
transcription coactivator activityGO:00037134.04
transcription cofactor activityGO:00037123.44
ion bindingGO:00431671.36
transferase activityGO:00167401.95
transferase activity, transferring one-carbon groupsGO:00167414.3
transcription factor activity, transcription factor bindingGO:00009893.36
transcription factor activity, protein bindingGO:00009883.35
metal ion bindingGO:00468721.41
cation bindingGO:00431691.4
S-adenosylmethionine-dependent methyltransferase activityGO:00087574.81
transcription factor bindingGO:00081343.46
SMAD bindingGO:00463325.45
catalytic activityGO:00038241.05
N-methyltransferase activityGO:00081705.26
organic cyclic compound bindingGO:00971591.05
protein bindingGO:00055150.46