Gene table of SUFU : SUFU negative regulator of hedgehog signaling

Gene-disease associations table

Disease IDDisease nameSource of annotation with SUFUOMIM linkNumber of associated genesgenes
607174MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TOOMIM link to OMIM 6PTEN, PDGFB, NF2, MN1, SUFU, SMARCE1
109400BASAL CELL NEVUS SYNDROMEClinVar, OMIM link to OMIM 3PTCH2, PTCH1, SUFU
155255MEDULLOBLASTOMAClinVar, OMIM link to OMIM 5APC, BRCA2, CTNNB1, PTCH2, SUFU

Download the gene annotation in CSV format

Annotation of the gene SUFU

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Hedgehog signaling pathwayhsa043407.01
Pathways in cancerhsa052003.98
Basal cell carcinomahsa052176.79
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Degradation of GLI2 by the proteasomeR-HSA-56107837.1
Degradation of GLI1 by the proteasomeR-HSA-56107807.1
Hedgehog 'off' stateR-HSA-56107876.19
GLI3 is processed to GLI3R by the proteasomeR-HSA-56107857.1
Hedgehog 'on' stateR-HSA-56326846.62
Signaling by HedgehogR-HSA-53583515.79
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
enzyme bindingGO:00198992.27
protein bindingGO:00055150.46
transcription factor bindingGO:00081343.46
transcription corepressor activityGO:00037144.33
transcription cofactor activityGO:00037123.44
beta-catenin bindingGO:00080135.3
transcription factor activity, transcription factor bindingGO:00009893.36
protein kinase bindingGO:00199013.44
kinase bindingGO:00199003.32
bindingGO:00054880.18
signal transducer activityGO:00048712.28
transcription factor activity, protein bindingGO:00009883.35