Disease ID | Disease name | Source of annotation with SUFU | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
607174 | MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TO | OMIM | link to OMIM | 6 | PTEN, PDGFB, NF2, MN1, SUFU, SMARCE1 |
109400 | BASAL CELL NEVUS SYNDROME | ClinVar, OMIM | link to OMIM | 3 | PTCH2, PTCH1, SUFU |
155255 | MEDULLOBLASTOMA | ClinVar, OMIM | link to OMIM | 5 | APC, BRCA2, CTNNB1, PTCH2, SUFU |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Hedgehog signaling pathway | hsa04340 | 7.01 |
Pathways in cancer | hsa05200 | 3.98 |
Basal cell carcinoma | hsa05217 | 6.79 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Degradation of GLI2 by the proteasome | R-HSA-5610783 | 7.1 |
Degradation of GLI1 by the proteasome | R-HSA-5610780 | 7.1 |
Hedgehog 'off' state | R-HSA-5610787 | 6.19 |
GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 7.1 |
Hedgehog 'on' state | R-HSA-5632684 | 6.62 |
Signaling by Hedgehog | R-HSA-5358351 | 5.79 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
enzyme binding | GO:0019899 | 2.27 |
protein binding | GO:0005515 | 0.46 |
transcription factor binding | GO:0008134 | 3.46 |
transcription corepressor activity | GO:0003714 | 4.33 |
transcription cofactor activity | GO:0003712 | 3.44 |
beta-catenin binding | GO:0008013 | 5.3 |
transcription factor activity, transcription factor binding | GO:0000989 | 3.36 |
protein kinase binding | GO:0019901 | 3.44 |
kinase binding | GO:0019900 | 3.32 |
binding | GO:0005488 | 0.18 |
signal transducer activity | GO:0004871 | 2.28 |
transcription factor activity, protein binding | GO:0000988 | 3.35 |