| Disease ID | Disease name | Source of annotation with TRIM32 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS253600 | MUSCULAR DYSTROPHY, LIMB-GIRDLE, AUTOSOMAL RECESSIVE | ClinVar, OMIM, HUMSAVAR | link to OMIM | 24 | SGCA, TCAP, SGCB, ISPD, BVES, POMK, POMT2, TRAPPC11, SGCD, TTN, FKTN, POMT1, TRIM32, LIMS2, ANO5, CAPN3, DYSF, FKRP, POMGNT1, SGCG, DAG1, GMPPB, DES, PLEC |
| PS209900 | BARDET-BIEDL SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 23 | ARL6, BBS7, KIF7, BBS12, BBS2, BBIP1, TMEM67, LZTFL1, BBS4, TRIM32, MKKS, CCDC28B, WDPCP, CEP290, BBS9, TTC8, BBS10, TTC21B, BBS5, IFT27, MKS1, BBS1, SDCCAG8 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Ubiquitin mediated proteolysis | hsa04120 | 5.63 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 9.08 |
| Immune System | R-HSA-168256 | 2.37 |
| Innate Immune System | R-HSA-168249 | 3.17 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 5.19 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 6.94 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| GO term | GO ID | GO IC |
|---|---|---|
| myosin binding | GO:0017022 | 5.66 |
| zinc ion binding | GO:0008270 | 2.66 |
| nucleic acid binding | GO:0003676 | 1.44 |
| translation initiation factor binding | GO:0031369 | 6.37 |
| ubiquitin protein ligase activity | GO:0061630 | 4.47 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| Tat protein binding | GO:0030957 | 7.66 |
| cation binding | GO:0043169 | 1.4 |
| transition metal ion binding | GO:0046914 | 2.48 |
| ligase activity | GO:0016874 | 3.72 |
| transcription coactivator activity | GO:0003713 | 4.04 |
| transcription cofactor activity | GO:0003712 | 3.44 |
| ion binding | GO:0043167 | 1.36 |
| transferase activity | GO:0016740 | 1.95 |
| transcription factor activity, transcription factor binding | GO:0000989 | 3.36 |
| transcription factor activity, protein binding | GO:0000988 | 3.35 |
| metal ion binding | GO:0046872 | 1.41 |
| ubiquitin-like protein transferase activity | GO:0019787 | 3.69 |
| transcription factor binding | GO:0008134 | 3.46 |
| catalytic activity | GO:0003824 | 1.05 |
| ubiquitin-protein transferase activity | GO:0004842 | 3.73 |
| protein self-association | GO:0043621 | 5.93 |
| ubiquitin-like protein ligase activity | GO:0061659 | 4.44 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| ubiquitin-like protein binding | GO:0032182 | 4.93 |
| ubiquitin binding | GO:0043130 | 5.09 |
| RNA binding | GO:0003723 | 2.36 |
| protein binding | GO:0005515 | 0.46 |
| binding | GO:0005488 | 0.18 |