| Disease ID | Disease name | Source of annotation with WNT1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 166710 | OSTEOPOROSIS | HUMSAVAR | link to OMIM | 7 | COL1A2, CALCR, PDLIM4, COL1A1, WNT1, VDR, LRP5 |
| PS166200 | OSTEOGENESIS IMPERFECTA | ClinVar, OMIM, HUMSAVAR | link to OMIM | 14 | FKBP10, PPIB, WNT1, BMP1, TMEM38B, P3H1, COL1A1, COL1A2, CRTAP, IFITM5, SPARC, SERPINF1, SP7, SERPINH1 |
| 615221 | BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 16 | ClinVar, OMIM | link to OMIM | 1 | WNT1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Signaling pathways regulating pluripotency of stem cells | hsa04550 | 5.6 |
| Hedgehog signaling pathway | hsa04340 | 7.01 |
| Proteoglycans in cancer | hsa05205 | 5.02 |
| Pathways in cancer | hsa05200 | 3.98 |
| Basal cell carcinoma | hsa05217 | 6.79 |
| Melanogenesis | hsa04916 | 5.97 |
| Hippo signaling pathway | hsa04390 | 5.37 |
| HTLV-I infection | hsa05166 | 4.59 |
| Wnt signaling pathway | hsa04310 | 5.49 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 6.52 |
| Signaling by Wnt | R-HSA-195721 | 4.79 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| beta-catenin independent WNT signaling | R-HSA-3858494 | 5.83 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 6.7 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 8.28 |
| PCP/CE pathway | R-HSA-4086400 | 6.47 |
| disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 8.03 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 5.36 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Developmental Biology | R-HSA-1266738 | 3.48 |
| GO term | GO ID | GO IC |
|---|---|---|
| transcription regulatory region DNA binding | GO:0044212 | 3.03 |
| cytokine activity | GO:0005125 | 4.34 |
| nucleic acid binding | GO:0003676 | 1.44 |
| protein binding | GO:0005515 | 0.46 |
| receptor agonist activity | GO:0048018 | 6.97 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| receptor activator activity | GO:0030546 | 6.27 |
| morphogen activity | GO:0016015 | 7.79 |
| regulatory region nucleic acid binding | GO:0001067 | 3.03 |
| receptor regulator activity | GO:0030545 | 5.91 |
| frizzled binding | GO:0005109 | 6.1 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| regulatory region DNA binding | GO:0000975 | 3.03 |
| G-protein coupled receptor binding | GO:0001664 | 4.18 |
| receptor binding | GO:0005102 | 2.43 |
| molecular function regulator | GO:0098772 | 2.51 |
| DNA binding | GO:0003677 | 1.92 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| protein domain specific binding | GO:0019904 | 3.32 |