Disease table of PITUITARY ADENOMA, GROWTH HORMONE-SECRETING, 1 OMIM ID: 102200

Gene-disease associations table

GeneAssociated with PITUITARY ADENOMA, GROWTH HORMONE-SECRETING, 1 inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
AIPClinVar, OMIMHGNC link11q13.23219090, 102200, 600634
GNASClinVar, OMIMHGNC link20q13.329612463, 103580, 166350, 174800, 219080, 102200, 219090, 603233, 612462

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
TFassociated to this disease# regulated genesRegulated genes# regulated genes associated with this diseaseRegulated genes associated with this disease
AIPYES5AHR, TFF1, NFKB2, GREB1, RSF10
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
GNASYES1GATA10
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
AIPGNASNo2GNAQ, EGFR

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
AIPGNASNo-1UBC

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: NET-GE enrichment (no shared terms)

NET-GE enrichment

Term New enriched termICP valueGenes
Nervous systemNEW3.770.022AIP, GNAS
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
catalytic activity (GO:0003824) 1.052AIP, GNAS
receptor binding (GO:0005102) 2.432AIP, GNAS
binding (GO:0005488) 0.182AIP, GNAS
signal transducer activity (GO:0004871) 2.282AIP, GNAS
protein binding (GO:0005515) 0.462AIP, GNAS
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
protein localization (GO:0008104) 2.362AIP, GNAS
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.432AIP, GNAS
regulation of primary metabolic process (GO:0080090) 1.082AIP, GNAS
regulation of metabolic process (GO:0019222) 1.022AIP, GNAS
regulation of cellular biosynthetic process (GO:0031326) 1.382AIP, GNAS
regulation of response to stimulus (GO:0048583) 1.542AIP, GNAS
signal transduction (GO:0007165) 1.282AIP, GNAS
regulation of signaling (GO:0023051) 1.722AIP, GNAS
regulation of cell communication (GO:0010646) 1.732AIP, GNAS
regulation of biological process (GO:0050789) 0.452AIP, GNAS
establishment of localization (GO:0051234) 1.482AIP, GNAS
cellular macromolecule metabolic process (GO:0044260) 0.932AIP, GNAS
regulation of signal transduction (GO:0009966) 1.842AIP, GNAS
organic substance metabolic process (GO:0071704) 0.632AIP, GNAS
biological regulation (GO:0065007) 0.392AIP, GNAS
organic substance transport (GO:0071702) 2.152AIP, GNAS
regulation of molecular function (GO:0065009) 1.782AIP, GNAS
macromolecule localization (GO:0033036) 2.342AIP, GNAS
transport (GO:0006810) 1.512AIP, GNAS
regulation of macromolecule metabolic process (GO:0060255) 1.082AIP, GNAS
regulation of cellular metabolic process (GO:0031323) 1.072AIP, GNAS
regulation of catalytic activity (GO:0050790) 1.972AIP, GNAS
regulation of biosynthetic process (GO:0009889) 1.372AIP, GNAS
regulation of cellular process (GO:0050794) 0.52AIP, GNAS
establishment of protein localization (GO:0045184) 2.532AIP, GNAS
macromolecule modification (GO:0043412) 1.732AIP, GNAS
regulation of nitrogen compound metabolic process (GO:0051171) 1.362AIP, GNAS
metabolic process (GO:0008152) 0.582AIP, GNAS
establishment of localization in cell (GO:0051649) 2.472AIP, GNAS
regulation of intracellular signal transduction (GO:1902531) 2.312AIP, GNAS
localization (GO:0051179) 1.42AIP, GNAS
cellular localization (GO:0051641) 2.322AIP, GNAS
regulation of hydrolase activity (GO:0051336) 2.532AIP, GNAS
primary metabolic process (GO:0044238) 0.692AIP, GNAS
intracellular transport (GO:0046907) 2.672AIP, GNAS
cellular metabolic process (GO:0044237) 0.692AIP, GNAS
macromolecule metabolic process (GO:0043170) 0.832AIP, GNAS
protein transport (GO:0015031) 2.622AIP, GNAS
cellular process (GO:0009987) 0.262AIP, GNAS
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cytoplasm (GO:0005737) 1.012AIP, GNAS
protein complex (GO:0043234) 1.512AIP, GNAS
macromolecular complex (GO:0032991) 1.352AIP, GNAS
cytosol (GO:0005829) 1.682AIP, GNAS
membrane (GO:0016020) 0.682AIP, GNAS
cell part (GO:0044464) 0.112AIP, GNAS
intracellular organelle part (GO:0044446) 0.812AIP, GNAS
cytoplasmic part (GO:0044444) 0.822AIP, GNAS
plasma membrane (GO:0005886) 1.392AIP, GNAS
intracellular part (GO:0044424) 0.282AIP, GNAS
organelle part (GO:0044422) 0.792AIP, GNAS