Disease table of ASTHMA, NASAL POLYPS, AND ASPIRIN INTOLERANCE OMIM ID: 208550

Gene-disease associations table

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Gene	Associated with ASTHMA, NASAL POLYPS, AND ASPIRIN INTOLERANCE in	Link to HGNC	Cytogenetic band	Number of associated diseases	Associated diseases
PTGER2	OMIM	HGNC link	14q22.1	1	208550
TBX21	OMIM	HGNC link	17q21.32	1	208550

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Tandem repeat annotations from DGD

Cytogenetic band analysis

Transcription Factors (TF) annotation from TRRUST

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TF	associated to this disease	# regulated genes	Regulated genes	# regulated genes associated with this disease	Regulated genes associated with this disease
TBX21	YES	14	IL12RB2, SPP1, GATA3, IL4, CXCR3, CHST4, IFNG, IL23R, NELFCD, CCR4, IL10, IL13, PTGDR2, FUT7	0

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regulated gene	associated to this disease	# TFs	TFs	# TFs associated with this disease	TFs associated with this disease
TBX21	YES	8	SP1, BCL6, STAT4, NFKB1, STAT1, RELA, PPARA, USF1	0
PTGER2	YES	2	SETBP1, PGR	0

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Interactions from BIOGRID - physical

Interactions from BIOGRID - genetic

Interactions from STRING

Gene1	Gene2	Direct Interaction	Interaction mode	Number of shared interactors	Shared genes in interaction
TBX21	PTGER2	No	-	1	VIP

Interactions from CORUM

Interactions from CENSUS

Interactions from PDB

Interactions from manually curated literature

KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)

REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)

GO - molecular function annotation: shared terms / NET-GE enrichment (no shared terms)

GO - biological process annotation: shared terms (no NET-GE enrichment)

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GO	IC	Number of genes with the same GO	Genes
response to external biotic stimulus (GO:0043207)	3.13	2	TBX21, PTGER2
response to biotic stimulus (GO:0009607)	3.09	2	TBX21, PTGER2
cellular response to organic substance (GO:0071310)	2.78	2	TBX21, PTGER2
cellular response to chemical stimulus (GO:0070887)	2.57	2	TBX21, PTGER2
response to external stimulus (GO:0009605)	2.55	2	TBX21, PTGER2
response to organic substance (GO:0010033)	2.2	2	TBX21, PTGER2
response to chemical (GO:0042221)	1.98	2	TBX21, PTGER2
cellular response to stimulus (GO:0051716)	1.97	2	TBX21, PTGER2
response to stimulus (GO:0050896)	1.22	2	TBX21, PTGER2
regulation of cellular process (GO:0050794)	0.5	2	TBX21, PTGER2

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GO - cellular component annotation: shared terms (no NET-GE enrichment)