Gene table of SETBP1 : SET binding protein 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SETBP1	OMIM link	Number of associated genes	genes
601626	LEUKEMIA, ACUTE MYELOID	HUMSAVAR	link to OMIM	23	FLT3, RUNX1, WHSC1L1, KIT, MLF1, CHIC2, CEBPA, LPP, SH3GL1, PICALM, NPM1, CBFB, ETV6, MLLT10, TERT, NUP214, JAK2, TGM6, GATA2, SETBP1, DDX41, NSD1, KRAS
608232	LEUKEMIA, CHRONIC MYELOID	HUMSAVAR	link to OMIM	2	BCR, SETBP1
269150	SCHINZEL-GIEDION MIDFACE RETRACTION SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	SETBP1
PS156200	MENTAL RETARDATION, AUTOSOMAL DOMINANT	ClinVar, OMIM	link to OMIM	44	EHMT1, MEF2C, AHDC1, SOX11, CDH15, KIRREL3, EEF1A2, KAT6A, ZMYND11, ARID1A, KMT2C, PPP2R5D, DYNC1H1, GRIN1, CTCF, SETD5, NR1I3, PACS1, DPP6, DEAF1, KIF1A, SYNGAP1, PURA, POGZ, EPB41L1, PPP2R1A, AUTS2, CTNNB1, ARID1B, ZBTB18, CACNG2, MBD5, SMARCB1, KANSL1, SMARCE1, COL4A3BP, MYT1L, ADNP, SMARCA4, GATAD2B, SETBP1, GRIN2B, CHAMP1, DYRK1A
614286	MYELODYSPLASTIC SYNDROME	HUMSAVAR	link to OMIM	5	SETBP1, SF3B1, GATA2, TET2, ASXL1
607785	JUVENILE MYELOMONOCYTIC LEUKEMIA	HUMSAVAR	link to OMIM	8	MLLT11, NF1, ARHGAP26, KRAS, SETBP1, PTPN11, CBL, NRAS

Download the gene annotation in CSV format

Annotation of the gene SETBP1

Associated genes in ENSEMBL

ENSG00000152217

Associated proteins - SwissProt Accession ID

Q9Y6X0

Associated PDB IDs

Cytogenetic Band

18q12.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
protein binding	GO:0005515	0.46
organic cyclic compound binding	GO:0097159	1.05
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06

--> -->

<type 'exceptions.KeyError'>

Python 2.7.9: /usr/bin/python
Fri Apr 26 00:01:06 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

/usr/lib/cgi-bin/gene_disease_db/gene.py in ()

475 kegg_ann(gene)

476 react_ann(gene)

=> 477 GOBPs,GOCCs=GO_ann(gene)

478 if make_file==True:

479 outcsv.close()

GOBPs undefined, GOCCs undefined, GO_ann = <function GO_ann>, gene = 'SETBP1'

/usr/lib/cgi-bin/gene_disease_db/gene.py in GO_ann(gene='SETBP1')

345 print '<summary id="missing"> Associated GO terms for '+root2root_names[root]+' </summary>'

346 print '</details>'

=> 347 return root2GO["biological_process"],root2GO["cellular_component"]

348

349 def kegg_ann(gene):

root2GO = {'cellular_component': set(['GO:0005634', 'GO:0043226', 'GO:0043227', 'GO:0043229', 'GO:0043231', 'GO:0044424', ...]), 'molecular_function': set(['GO:0003676', 'GO:0003677', 'GO:0005488', 'GO:0005515', 'GO:0097159', 'GO:1901363'])}

<type 'exceptions.KeyError'>: 'biological_process'
args = ('biological_process',)
message = 'biological_process'