Disease table of CHILBLAIN LUPUS OMIM ID: PS610448

Gene-disease associations table

GeneAssociated with CHILBLAIN LUPUS inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
TREX1ClinVar, OMIM, HUMSAVARHGNC link3p21.314PS225750, 192315, PS610448, 152700
SAMHD1ClinVar, OMIM, HUMSAVARHGNC link20q11.232PS610448, PS225750

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms (no NET-GE enrichment)

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Immune SystemR-HSA-1682562.372SAMHD1, TREX1
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cation binding (GO:0043169) 1.42SAMHD1, TREX1
protein binding (GO:0005515) 0.462SAMHD1, TREX1
hydrolase activity (GO:0016787) 1.92SAMHD1, TREX1
organic cyclic compound binding (GO:0097159) 1.052SAMHD1, TREX1
hydrolase activity, acting on ester bonds (GO:0016788) 3.12SAMHD1, TREX1
ion binding (GO:0043167) 1.362SAMHD1, TREX1
catalytic activity (GO:0003824) 1.052SAMHD1, TREX1
binding (GO:0005488) 0.182SAMHD1, TREX1
nucleic acid binding (GO:0003676) 1.442SAMHD1, TREX1
metal ion binding (GO:0046872) 1.412SAMHD1, TREX1
heterocyclic compound binding (GO:1901363) 1.062SAMHD1, TREX1

NET-GE enrichment

Term New enriched termICP valueGenes
purine deoxyribonucleotide binding (GO:0032554) NEW8.130.0SAMHD1, TREX1
deoxyribonucleotide binding (GO:0032552) NEW7.950.0SAMHD1, TREX1
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
nucleobase-containing compound metabolic process (GO:0006139) 1.352SAMHD1, TREX1
primary metabolic process (GO:0044238) 0.692SAMHD1, TREX1
response to stimulus (GO:0050896) 1.222SAMHD1, TREX1
cellular process (GO:0009987) 0.262SAMHD1, TREX1
cellular aromatic compound metabolic process (GO:0006725) 1.32SAMHD1, TREX1
cellular nitrogen compound metabolic process (GO:0034641) 1.222SAMHD1, TREX1
cellular metabolic process (GO:0044237) 0.692SAMHD1, TREX1
organic substance metabolic process (GO:0071704) 0.632SAMHD1, TREX1
response to stress (GO:0006950) 1.82SAMHD1, TREX1
nitrogen compound metabolic process (GO:0006807) 1.132SAMHD1, TREX1
biological regulation (GO:0065007) 0.392SAMHD1, TREX1
metabolic process (GO:0008152) 0.582SAMHD1, TREX1
regulation of biological process (GO:0050789) 0.452SAMHD1, TREX1
organic cyclic compound metabolic process (GO:1901360) 1.262SAMHD1, TREX1
heterocycle metabolic process (GO:0046483) 1.312SAMHD1, TREX1
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
intracellular membrane-bounded organelle (GO:0043231) 0.62SAMHD1, TREX1
nucleus (GO:0005634) 1.072SAMHD1, TREX1
membrane (GO:0016020) 0.682SAMHD1, TREX1
cell part (GO:0044464) 0.112SAMHD1, TREX1
intracellular organelle part (GO:0044446) 0.812SAMHD1, TREX1
intracellular organelle (GO:0043229) 0.512SAMHD1, TREX1
nuclear part (GO:0044428) 1.552SAMHD1, TREX1
intracellular part (GO:0044424) 0.282SAMHD1, TREX1
membrane-bounded organelle (GO:0043227) 0.472SAMHD1, TREX1
organelle (GO:0043226) 0.42SAMHD1, TREX1
organelle part (GO:0044422) 0.792SAMHD1, TREX1