cellular process (GO:0009987) | 0.26 | 5 | CTLA4, PTPN22, TREX1, DNASE1, FCGR2B |
biological regulation (GO:0065007) | 0.39 | 5 | CTLA4, PTPN22, TREX1, FCGR2A, FCGR2B |
regulation of biological process (GO:0050789) | 0.45 | 5 | CTLA4, PTPN22, TREX1, FCGR2A, FCGR2B |
regulation of immune response (GO:0050776) | 2.98 | 4 | CTLA4, PTPN22, FCGR2A, FCGR2B |
response to stimulus (GO:0050896) | 1.22 | 4 | CTLA4, PTPN22, TREX1, FCGR2B |
regulation of response to stimulus (GO:0048583) | 1.54 | 4 | CTLA4, PTPN22, FCGR2A, FCGR2B |
regulation of cellular process (GO:0050794) | 0.5 | 4 | CTLA4, PTPN22, FCGR2A, FCGR2B |
immune system process (GO:0002376) | 2.29 | 4 | CTLA4, PTPN22, FCGR2A, FCGR2B |
regulation of immune system process (GO:0002682) | 2.5 | 4 | CTLA4, PTPN22, FCGR2A, FCGR2B |
signal transduction (GO:0007165) | 1.28 | 4 | CTLA4, PTPN22, FCGR2A, FCGR2B |
primary metabolic process (GO:0044238) | 0.69 | 3 | PTPN22, TREX1, DNASE1 |
cellular response to stimulus (GO:0051716) | 1.97 | 3 | CTLA4, PTPN22, TREX1 |
immune response-activating cell surface receptor signaling pathway (GO:0002429) | 4.06 | 3 | CTLA4, PTPN22, FCGR2A |
immune response-regulating signaling pathway (GO:0002764) | 3.72 | 3 | CTLA4, PTPN22, FCGR2A |
cellular macromolecule metabolic process (GO:0044260) | 0.93 | 3 | PTPN22, TREX1, DNASE1 |
immune response-regulating cell surface receptor signaling pathway (GO:0002768) | 3.96 | 3 | CTLA4, PTPN22, FCGR2A |
positive regulation of response to stimulus (GO:0048584) | 2.18 | 3 | CTLA4, PTPN22, FCGR2A |
positive regulation of immune response (GO:0050778) | 3.4 | 3 | CTLA4, PTPN22, FCGR2A |
cellular metabolic process (GO:0044237) | 0.69 | 3 | PTPN22, TREX1, DNASE1 |
macromolecule metabolic process (GO:0043170) | 0.83 | 3 | PTPN22, TREX1, DNASE1 |
regulation of multicellular organismal process (GO:0051239) | 1.87 | 3 | CTLA4, PTPN22, TREX1 |
organic substance metabolic process (GO:0071704) | 0.63 | 3 | PTPN22, TREX1, DNASE1 |
positive regulation of immune system process (GO:0002684) | 2.96 | 3 | CTLA4, PTPN22, FCGR2A |
immune response-activating signal transduction (GO:0002757) | 3.8 | 3 | CTLA4, PTPN22, FCGR2A |
cell surface receptor signaling pathway (GO:0007166) | 2.09 | 3 | CTLA4, PTPN22, FCGR2A |
positive regulation of biological process (GO:0048518) | 1.2 | 3 | CTLA4, PTPN22, FCGR2A |
activation of immune response (GO:0002253) | 3.67 | 3 | CTLA4, PTPN22, FCGR2A |
metabolic process (GO:0008152) | 0.58 | 3 | PTPN22, TREX1, DNASE1 |
regulation of mononuclear cell proliferation (GO:0032944) | 4.45 | 2 | CTLA4, PTPN22 |
negative regulation of T cell activation (GO:0050868) | 5.26 | 2 | CTLA4, PTPN22 |
regulation of cell activation (GO:0050865) | 3.53 | 2 | CTLA4, PTPN22 |
positive regulation of cell activation (GO:0050867) | 3.97 | 2 | CTLA4, PTPN22 |
negative regulation of cell activation (GO:0050866) | 4.67 | 2 | CTLA4, PTPN22 |
regulation of T cell activation (GO:0050863) | 4.05 | 2 | CTLA4, PTPN22 |
nucleic acid metabolic process (GO:0090304) | 1.46 | 2 | DNASE1, TREX1 |
regulation of cell-cell adhesion (GO:0022407) | 3.79 | 2 | CTLA4, PTPN22 |
negative regulation of cell adhesion (GO:0007162) | 4.33 | 2 | CTLA4, PTPN22 |
nitrogen compound metabolic process (GO:0006807) | 1.13 | 2 | DNASE1, TREX1 |
negative regulation of cell-cell adhesion (GO:0022408) | 4.84 | 2 | CTLA4, PTPN22 |
single-organism process (GO:0044699) | 0.48 | 2 | PTPN22, DNASE1 |
positive regulation of cell-cell adhesion (GO:0022409) | 4.23 | 2 | CTLA4, PTPN22 |
nucleobase-containing compound metabolic process (GO:0006139) | 1.35 | 2 | DNASE1, TREX1 |
regulation of lymphocyte activation (GO:0051249) | 3.73 | 2 | CTLA4, PTPN22 |
positive regulation of cell adhesion (GO:0045785) | 3.79 | 2 | CTLA4, PTPN22 |
organic cyclic compound metabolic process (GO:1901360) | 1.26 | 2 | DNASE1, TREX1 |
negative regulation of multicellular organismal process (GO:0051241) | 2.84 | 2 | CTLA4, PTPN22 |
regulation of cytokine production (GO:0001817) | 3.4 | 2 | PTPN22, TREX1 |
negative regulation of leukocyte cell-cell adhesion (GO:1903038) | 5.19 | 2 | CTLA4, PTPN22 |
positive regulation of leukocyte cell-cell adhesion (GO:1903039) | 4.35 | 2 | CTLA4, PTPN22 |
regulation of leukocyte proliferation (GO:0070663) | 4.4 | 2 | CTLA4, PTPN22 |
negative regulation of immune system process (GO:0002683) | 3.85 | 2 | CTLA4, PTPN22 |
negative regulation of biological process (GO:0048519) | 1.33 | 2 | CTLA4, PTPN22 |
regulation of cell adhesion (GO:0030155) | 3.27 | 2 | CTLA4, PTPN22 |
regulation of leukocyte cell-cell adhesion (GO:1903037) | 4.01 | 2 | CTLA4, PTPN22 |
regulation of cell proliferation (GO:0042127) | 2.41 | 2 | CTLA4, PTPN22 |
antigen receptor-mediated signaling pathway (GO:0050851) | 4.43 | 2 | CTLA4, PTPN22 |
cellular aromatic compound metabolic process (GO:0006725) | 1.3 | 2 | DNASE1, TREX1 |
positive regulation of T cell activation (GO:0050870) | 4.39 | 2 | CTLA4, PTPN22 |
cellular response to DNA damage stimulus (GO:0006974) | 3.17 | 2 | CTLA4, TREX1 |
response to stress (GO:0006950) | 1.8 | 2 | CTLA4, TREX1 |
single-organism cellular process (GO:0044763) | 0.65 | 2 | PTPN22, DNASE1 |
immune response (GO:0006955) | 2.86 | 2 | CTLA4, FCGR2B |
heterocycle metabolic process (GO:0046483) | 1.31 | 2 | DNASE1, TREX1 |
nucleic acid phosphodiester bond hydrolysis (GO:0090305) | 4.12 | 2 | DNASE1, TREX1 |
positive regulation of lymphocyte activation (GO:0051251) | 4.07 | 2 | CTLA4, PTPN22 |
negative regulation of lymphocyte activation (GO:0051250) | 4.95 | 2 | CTLA4, PTPN22 |
regulation of lymphocyte proliferation (GO:0050670) | 4.46 | 2 | CTLA4, PTPN22 |
cellular nitrogen compound metabolic process (GO:0034641) | 1.22 | 2 | DNASE1, TREX1 |
negative regulation of leukocyte activation (GO:0002695) | 4.79 | 2 | CTLA4, PTPN22 |
regulation of leukocyte activation (GO:0002694) | 3.6 | 2 | CTLA4, PTPN22 |
positive regulation of leukocyte activation (GO:0002696) | 4.0 | 2 | CTLA4, PTPN22 |
cellular response to stress (GO:0033554) | 2.51 | 2 | CTLA4, TREX1 |
regulation of type I interferon production (GO:0032479) | 5.03 | 2 | PTPN22, TREX1 |
DNA metabolic process (GO:0006259) | 3.09 | 2 | DNASE1, TREX1 |
negative regulation of cellular process (GO:0048523) | 1.41 | 2 | CTLA4, PTPN22 |
positive regulation of cellular process (GO:0048522) | 1.3 | 2 | CTLA4, PTPN22 |