| Disease ID | Disease name | Source of annotation with CBX2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS400044 | 46,XY SEX REVERSAL | ClinVar, OMIM, HUMSAVAR | link to OMIM | 9 | AKR1C2, AKR1C4, NR0B1, SRY, MAP3K1, CBX2, NR5A1, DHH, ZFPM2 |
Download the gene annotation in CSV format
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 6.51 |
| Cellular Senescence | R-HSA-2559583 | 5.7 |
| SUMO E3 ligases SUMOylate target proteins | R-HSA-3108232 | 6.77 |
| Cellular responses to stress | R-HSA-2262752 | 4.56 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| SUMOylation | R-HSA-2990846 | 6.68 |
| SUMOylation of DNA damage response and repair proteins | R-HSA-3108214 | 6.77 |
| Post-translational protein modification | R-HSA-597592 | 4.54 |
| GO term | GO ID | GO IC |
|---|---|---|
| histone binding | GO:0042393 | 4.72 |
| methylated histone binding | GO:0035064 | 5.81 |
| nucleic acid binding | GO:0003676 | 1.44 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| DNA binding | GO:0003677 | 1.92 |
| chromatin binding | GO:0003682 | 3.64 |
| heterocyclic compound binding | GO:1901363 | 1.06 |