Gene table of DNM1 : dynamin 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with DNM1	OMIM link	Number of associated genes	genes
PS308350	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE	ClinVar, OMIM, HUMSAVAR	link to OMIM	37	KCNT1, EEF1A2, SZT2, ALG13, ST3GAL3, WWOX, ITPA, SIK1, SCN1A, ARHGEF9, GNAO1, TBC1D24, DNM1, SLC35A2, GRIN2B, SLC13A5, SLC25A22, HCN1, KCNB1, STXBP1, SCN9A, PNKP, KCNQ2, SPTAN1, KCNA2, SCN2A, PLCB1, AARS, PCDH19, CDKL5, GABRA1, SLC12A5, DOCK7, ARX, SCN8A, NECAP1, PIGA

Download the gene annotation in CSV format

Annotation of the gene DNM1

Associated genes in ENSEMBL

ENSG00000106976

Associated proteins - SwissProt Accession ID

Q05193

Associated PDB IDs

Cytogenetic Band

9q34.11

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Synaptic vesicle cycle	hsa04721	6.74
Endocrine and other factor-regulated calcium reabsorption	hsa04961	7.12
Endocytosis	hsa04144	4.92
Bacterial invasion of epithelial cells	hsa05100	6.34

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Immune System	R-HSA-168256	2.37
Recycling pathway of L1	R-HSA-437239	7.62
Adaptive Immune System	R-HSA-1280218	3.19
Developmental Biology	R-HSA-1266738	3.48
Signalling by NGF	R-HSA-166520	4.23
Gap junction trafficking	R-HSA-190828	7.59
Toll-Like Receptors Cascades	R-HSA-168898	5.91
L1CAM interactions	R-HSA-373760	6.19
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	6.11
Innate Immune System	R-HSA-168249	3.17
Membrane Trafficking	R-HSA-199991	5.26
Gap junction degradation	R-HSA-190873	9.4
Gap junction trafficking and regulation	R-HSA-157858	7.52
EPH-Ephrin signaling	R-HSA-2682334	6.43
Axon guidance	R-HSA-422475	3.93
NGF signalling via TRKA from the plasma membrane	R-HSA-187037	4.51
Vesicle-mediated transport	R-HSA-5653656	4.33
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	7.34
Formation of annular gap junctions	R-HSA-196025	9.52
MHC class II antigen presentation	R-HSA-2132295	6.01
Retrograde neurotrophin signalling	R-HSA-177504	9.28
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
protein C-terminus binding	GO:0008022	4.5
purine ribonucleoside triphosphate binding	GO:0035639	2.22
enzyme binding	GO:0019899	2.27
dopamine receptor binding	GO:0050780	6.85
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
G-protein coupled receptor binding	GO:0001664	4.18
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
pyrophosphatase activity	GO:0016462	3.04
small molecule binding	GO:0036094	1.89
nucleotide binding	GO:0000166	1.96
guanyl ribonucleotide binding	GO:0032561	3.73
purine nucleoside binding	GO:0001883	2.22
ribonucleoside binding	GO:0032549	2.22
protein complex binding	GO:0032403	3.09
purine nucleotide binding	GO:0017076	2.19
identical protein binding	GO:0042802	2.63
GTP binding	GO:0005525	3.78
hydrolase activity	GO:0016787	1.9
D2 dopamine receptor binding	GO:0031749	8.35
poly(A) RNA binding	GO:0044822	2.69
GTPase activity	GO:0003924	4.31
nucleoside-triphosphatase activity	GO:0017111	3.09
protein kinase binding	GO:0019901	3.44
catalytic activity	GO:0003824	1.05
protein dimerization activity	GO:0046983	2.72
nitric-oxide synthase binding	GO:0050998	6.91
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	3.03
kinase binding	GO:0019900	3.32
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
hydrolase activity, acting on acid anhydrides	GO:0016817	3.03
guanyl nucleotide binding	GO:0019001	3.73
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46
purine ribonucleotide binding	GO:0032555	2.2
macromolecular complex binding	GO:0044877	2.61
receptor binding	GO:0005102	2.43
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19