Gene table of WWOX : WW domain containing oxidoreductase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with WWOX	OMIM link	Number of associated genes	genes
133239	ESOPHAGEAL CANCER	OMIM	link to OMIM	7	TGFBR2, DCC, DLEC1, RNF6, DEC1, WWOX, LZTS1
614322	SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 12	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	WWOX
PS308350	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE	ClinVar, OMIM, HUMSAVAR	link to OMIM	37	KCNT1, EEF1A2, SZT2, ALG13, ST3GAL3, WWOX, ITPA, SIK1, SCN1A, ARHGEF9, GNAO1, TBC1D24, DNM1, SLC35A2, GRIN2B, SLC13A5, SLC25A22, HCN1, KCNB1, STXBP1, SCN9A, PNKP, KCNQ2, SPTAN1, KCNA2, SCN2A, PLCB1, AARS, PCDH19, CDKL5, GABRA1, SLC12A5, DOCK7, ARX, SCN8A, NECAP1, PIGA

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
coenzyme binding	GO:0050662	4.53
transcriptional repressor activity, RNA polymerase II transcription factor binding	GO:0001191	5.28
transcriptional activator activity, RNA polymerase II transcription factor binding	GO:0001190	5.77
protein binding	GO:0005515	0.46
catalytic activity	GO:0003824	1.05
transcriptional repressor activity, RNA polymerase II activating transcription factor binding	GO:0098811	5.77
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
enzyme binding	GO:0019899	2.27
RNA polymerase II transcription cofactor activity	GO:0001104	5.22
RNA polymerase II transcription coactivator activity	GO:0001105	6.15
transcription factor activity, RNA polymerase II transcription factor binding	GO:0001076	4.84
cofactor binding	GO:0048037	4.16
binding	GO:0005488	0.18
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
protein dimerization activity	GO:0046983	2.72
oxidoreductase activity	GO:0016491	3.12