| Disease ID | Disease name | Source of annotation with HGF | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS220290 | DEAFNESS, AUTOSOMAL RECESSIVE | ClinVar, OMIM | link to OMIM | 60 | CLIC5, KARS, OTOGL, CABP2, HGF, DFNB59, GIPC3, EPS8, MYO3A, CDH23, OTOF, ELMOD3, ESRRB, RDX, GJB2, GJB3, ESPN, ADCY1, CIB2, STRC, TMIE, S1PR2, FAM65B, TSPEAR, TBC1D24, SLC26A4, OTOG, COL11A2, MARVELD2, PNPT1, MYO15A, WHRN, CLDN14, MYO7A, GJB6, MET, TPRN, DCDC2, LRTOMT, TMC1, MYO6, ILDR1, MSRB3, SERPINB6, SLC26A5, ATP2B2, LHFPL5, SYNE4, GRXCR2, FOXI1, GRXCR1, LOXHD1, TECTA, PCDH15, TRIOBP, USH1C, KCNJ10, PTPRQ, TMPRSS3, OTOA |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Melanoma | hsa05218 | 6.56 |
| Focal adhesion | hsa04510 | 4.92 |
| Proteoglycans in cancer | hsa05205 | 5.02 |
| Renal cell carcinoma | hsa05211 | 6.6 |
| Pathways in cancer | hsa05200 | 3.98 |
| Rap1 signaling pathway | hsa04015 | 4.97 |
| Ras signaling pathway | hsa04014 | 4.9 |
| Malaria | hsa05144 | 7.15 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Interleukin-7 signaling | R-HSA-1266695 | 9.52 |
| Platelet degranulation | R-HSA-114608 | 6.68 |
| Signaling by Interleukins | R-HSA-449147 | 4.71 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
| Immune System | R-HSA-168256 | 2.37 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.59 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| Hemostasis | R-HSA-109582 | 3.98 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| endopeptidase activity | GO:0004175 | 3.63 |
| growth factor activity | GO:0008083 | 4.66 |
| peptidase activity | GO:0008233 | 3.23 |
| serine-type endopeptidase activity | GO:0004252 | 4.4 |
| serine hydrolase activity | GO:0017171 | 4.26 |
| chemoattractant activity | GO:0042056 | 6.48 |
| catalytic activity | GO:0003824 | 1.05 |
| peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| protein heterodimerization activity | GO:0046982 | 3.64 |
| protein dimerization activity | GO:0046983 | 2.72 |
| identical protein binding | GO:0042802 | 2.63 |
| serine-type peptidase activity | GO:0008236 | 4.27 |