Gene table of SETD1A : SET domain containing 1A

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SETD1A	OMIM link	Number of associated genes	genes
181500	SCHIZOPHRENIA	ClinVar	link to OMIM	17	COMT, DISC2, MTHFR, DISC1, CHI3L1, SYN2, MC4R, DAO, AKT1, HTR2A, APOL2, DTNBP1, SETD1A, DRD3, APOL4, RTN4R, DAOA

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Lysine degradation	hsa00310	7.01

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Chromatin organization	R-HSA-4839726	5.19
PKMTs methylate histone lysines	R-HSA-3214841	7.66
Chromatin modifying enzymes	R-HSA-3247509	5.19

Associated GO terms for Molecular function

GO term	GO ID	GO IC
histone-lysine N-methyltransferase activity	GO:0018024	5.93
histone methyltransferase activity	GO:0042054	5.68
lysine N-methyltransferase activity	GO:0016278	5.7
protein-lysine N-methyltransferase activity	GO:0016279	5.71
protein methyltransferase activity	GO:0008276	5.33
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
methyltransferase activity	GO:0008168	4.35
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleotide binding	GO:0000166	1.96
transferase activity	GO:0016740	1.95
transferase activity, transferring one-carbon groups	GO:0016741	4.3
histone methyltransferase activity (H3-K4 specific)	GO:0042800	6.85
S-adenosylmethionine-dependent methyltransferase activity	GO:0008757	4.81
beta-catenin binding	GO:0008013	5.3
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
N-methyltransferase activity	GO:0008170	5.26
organic cyclic compound binding	GO:0097159	1.05
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46