| Disease ID | Disease name | Source of annotation with SLC25A4 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS603041 | MITOCHONDRIAL DNA DEPLETION SYNDROME | ClinVar, OMIM | link to OMIM | 14 | RRM2B, SLC25A4, AGK, C10orf2, FBXL4, SUCLG1, MGME1, POLG, MPV17, TK2, SUCLA2, DGUOK, OPA1, TYMP |
| PS157640 | PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MTDNA DELETIONS | ClinVar, OMIM, HUMSAVAR | link to OMIM | 7 | SLC25A4, DNA2, C10orf2, RRM2B, RNASEH1, POLG, POLG2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| cGMP-PKG signaling pathway | hsa04022 | 5.32 |
| Calcium signaling pathway | hsa04020 | 5.22 |
| HTLV-I infection | hsa05166 | 4.59 |
| Huntington's disease | hsa05016 | 5.17 |
| Parkinson's disease | hsa05012 | 5.59 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| Host Interactions of HIV factors | R-HSA-162909 | 5.99 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 7.89 |
| Regulation of insulin secretion | R-HSA-422356 | 6.66 |
| Mitochondrial protein import | R-HSA-1268020 | 7.28 |
| Integration of energy metabolism | R-HSA-163685 | 6.24 |
| HIV Infection | R-HSA-162906 | 5.22 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization | R-HSA-180897 | 11.4 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Disease | R-HSA-1643685 | 3.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| substrate-specific transmembrane transporter activity | GO:0022891 | 2.9 |
| purine nucleobase transmembrane transporter activity | GO:0005345 | 7.95 |
| transporter activity | GO:0005215 | 2.57 |
| nucleobase transmembrane transporter activity | GO:0015205 | 7.66 |
| structural molecule activity | GO:0005198 | 3.1 |
| structural constituent of ribosome | GO:0003735 | 4.32 |
| transmembrane transporter activity | GO:0022857 | 2.82 |
| substrate-specific transporter activity | GO:0022892 | 2.72 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| adenine transmembrane transporter activity | GO:0015207 | 8.64 |