Disease table of TUMORAL CALCINOSIS, HYPERPHOSPHATEMIC, FAMILIAL OMIM ID: 211900

Gene-disease associations table

Gene	Associated with TUMORAL CALCINOSIS, HYPERPHOSPHATEMIC, FAMILIAL in	Link to HGNC	Cytogenetic band	Number of associated diseases	Associated diseases
KL	OMIM, HUMSAVAR	HGNC link	13q13.1	1	211900
FGF23	ClinVar, OMIM, HUMSAVAR	HGNC link	12p13.32	2	PS193100, 211900
GALNT3	ClinVar, OMIM	HGNC link	2q24.3	1	211900

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD

Cytogenetic band analysis

Transcription Factors (TF) annotation from TRRUST

regulated gene	associated to this disease	# TFs	TFs	# TFs associated with this disease	TFs associated with this disease
KL	YES	1	HMGA1	0
GALNT3	YES	2	NRF1, TFAP2A	0

Interactions from BIOGRID - physical

Interactions from BIOGRID - genetic

Interactions from STRING

Gene1	Gene2	Direct Interaction	Interaction mode	Number of shared interactors	Shared genes in interaction
KL	FGF23	Yes	activation, binding	2	FGFR1, FGFR4
KL	GALNT3	No	-	1	FGF23
FGF23	GALNT3	Yes	activation, ptmod	0

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM

Interactions from CENSUS

Interactions from PDB

Interactions from manually curated literature

Gene1	Gene2	Direct interaction	More information
FGF23	GALNT3	yes, they interact	GALNT3 Glycosylates FGF23. [UniProt]
FGF23	KL	yes, they interact	FGF23 upregulates EGR1 expression in the presence of KL. [UniProt]
GALNT3	KL	No

KEGG pathways annotation: shared terms (no NET-GE enrichment)

Shared terms

KEGG term	KEGG term ID	IC	Number of genes with the same term	Genes
Metabolic pathways	hsa01100	2.49	2	GALNT3, KL

REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME term	REACTOME term ID	IC	Number of genes with the same term	Genes
Interleukin-2 signaling	R-HSA-451927	5.05	2	FGF23, KL
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	4.62	2	FGF23, KL
GAB1 signalosome	R-HSA-180292	6.31	2	FGF23, KL
Developmental Biology	R-HSA-1266738	3.48	2	FGF23, KL
Signaling by VEGF	R-HSA-194138	4.66	2	FGF23, KL
FCERI mediated MAPK activation	R-HSA-2871796	4.32	2	FGF23, KL
IRS-mediated signalling	R-HSA-112399	4.87	2	FGF23, KL
VEGFA-VEGFR2 Pathway	R-HSA-4420097	4.7	2	FGF23, KL
Signaling by EGFR	R-HSA-177929	4.59	2	FGF23, KL
PI-3K cascade:FGFR3	R-HSA-5654710	6.37	2	FGF23, KL
DAP12 interactions	R-HSA-2172127	4.56	2	FGF23, KL
Downstream signaling of activated FGFR4	R-HSA-5654716	4.71	2	FGF23, KL
Signaling by ERBB2	R-HSA-1227986	4.66	2	FGF23, KL
VEGFR2 mediated cell proliferation	R-HSA-5218921	5.07	2	FGF23, KL
PI3K/AKT activation	R-HSA-198203	6.32	2	FGF23, KL
Immune System	R-HSA-168256	2.37	2	FGF23, KL
Frs2-mediated activation	R-HSA-170968	5.12	2	FGF23, KL
PI3K events in ERBB2 signaling	R-HSA-1963642	6.37	2	FGF23, KL
Downstream signal transduction	R-HSA-186763	4.65	2	FGF23, KL
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	4.95	2	FGF23, KL
Signalling to p38 via RIT and RIN	R-HSA-187706	5.12	2	FGF23, KL
FRS-mediated FGFR2 signaling	R-HSA-5654700	5.14	2	FGF23, KL
SOS-mediated signalling	R-HSA-112412	5.15	2	FGF23, KL
FRS-mediated FGFR3 signaling	R-HSA-5654706	5.14	2	FGF23, KL
Downstream signaling of activated FGFR3	R-HSA-5654708	4.71	2	FGF23, KL
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	4.03	2	FGF23, KL
Interleukin receptor SHC signaling	R-HSA-912526	5.09	2	FGF23, KL
Innate Immune System	R-HSA-168249	3.17	2	FGF23, KL
NGF signalling via TRKA from the plasma membrane	R-HSA-187037	4.51	2	FGF23, KL
Prolonged ERK activation events	R-HSA-169893	5.11	2	FGF23, KL
Signaling by FGFR2	R-HSA-5654738	4.68	2	FGF23, KL
GRB2 events in EGFR signaling	R-HSA-179812	5.15	2	FGF23, KL
Signaling by FGFR1	R-HSA-5654736	4.69	2	FGF23, KL
PI3K events in ERBB4 signaling	R-HSA-1250342	6.37	2	FGF23, KL
PI3K Cascade	R-HSA-109704	6.68	2	FGF23, KL
Axon guidance	R-HSA-422475	3.93	2	FGF23, KL
SHC-mediated cascade:FGFR1	R-HSA-5654688	8.59	2	FGF23, KL
FGFR1 ligand binding and activation	R-HSA-190242	8.98	2	FGF23, KL
Signaling by Leptin	R-HSA-2586552	5.1	2	FGF23, KL
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	7.05	2	FGF23, KL
IGF1R signaling cascade	R-HSA-2428924	4.85	2	FGF23, KL
IRS-related events triggered by IGF1R	R-HSA-2428928	4.85	2	FGF23, KL
Signaling by Insulin receptor	R-HSA-74752	4.73	2	FGF23, KL
Disease	R-HSA-1643685	3.33	2	FGF23, KL
Insulin receptor signalling cascade	R-HSA-74751	4.85	2	FGF23, KL
FGFR1c and Klotho ligand binding and activation	R-HSA-190374	11.4	2	FGF23, KL
Downstream signaling of activated FGFR1	R-HSA-5654687	4.71	2	FGF23, KL
PI-3K cascade:FGFR4	R-HSA-5654720	6.37	2	FGF23, KL
PI-3K cascade:FGFR1	R-HSA-5654689	6.37	2	FGF23, KL
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	4.26	2	FGF23, KL
Negative regulation of FGFR1 signaling	R-HSA-5654726	7.98	2	FGF23, KL
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	5.59	2	FGF23, KL
PI3K/AKT Signaling in Cancer	R-HSA-2219528	6.56	2	FGF23, KL
Diseases of signal transduction	R-HSA-5663202	4.89	2	FGF23, KL
GRB2 events in ERBB2 signaling	R-HSA-1963640	5.15	2	FGF23, KL
Signalling to RAS	R-HSA-167044	5.08	2	FGF23, KL
PI-3K cascade:FGFR2	R-HSA-5654695	6.37	2	FGF23, KL
Downstream signaling of activated FGFR2	R-HSA-5654696	4.71	2	FGF23, KL
SHC1 events in EGFR signaling	R-HSA-180336	5.15	2	FGF23, KL
FRS-mediated FGFR1 signaling	R-HSA-5654693	5.14	2	FGF23, KL
SHC1 events in ERBB2 signaling	R-HSA-1250196	5.15	2	FGF23, KL
ARMS-mediated activation	R-HSA-170984	5.12	2	FGF23, KL
SHC1 events in ERBB4 signaling	R-HSA-1250347	5.15	2	FGF23, KL
Signaling by PDGF	R-HSA-186797	4.53	2	FGF23, KL
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	4.85	2	FGF23, KL
Signaling by Interleukins	R-HSA-449147	4.71	2	FGF23, KL
Cytokine Signaling in Immune system	R-HSA-1280215	3.74	2	FGF23, KL
Signaling by ERBB4	R-HSA-1236394	4.7	2	FGF23, KL
MAPK1/MAPK3 signaling	R-HSA-5684996	5.11	2	FGF23, KL
Adaptive Immune System	R-HSA-1280218	3.19	2	FGF23, KL
MAPK family signaling cascades	R-HSA-5683057	4.89	2	FGF23, KL
Signalling by NGF	R-HSA-166520	4.23	2	FGF23, KL
Phospholipase C-mediated cascade: FGFR1	R-HSA-5654219	7.43	2	FGF23, KL
RAF/MAP kinase cascade	R-HSA-5673001	5.15	2	FGF23, KL
Signaling by FGFR4	R-HSA-5654743	4.69	2	FGF23, KL
Signaling by FGFR3	R-HSA-5654741	4.69	2	FGF23, KL
Signaling by FGFR	R-HSA-190236	4.67	2	FGF23, KL
Signaling by SCF-KIT	R-HSA-1433557	4.73	2	FGF23, KL
NCAM signaling for neurite out-growth	R-HSA-375165	4.9	2	FGF23, KL
DAP12 signaling	R-HSA-2424491	4.64	2	FGF23, KL
Interleukin-3, 5 and GM-CSF signaling	R-HSA-512988	4.99	2	FGF23, KL
FRS-mediated FGFR4 signaling	R-HSA-5654712	5.14	2	FGF23, KL
PIP3 activates AKT signaling	R-HSA-1257604	6.37	2	FGF23, KL
Signaling by GPCR	R-HSA-372790	2.68	2	FGF23, KL
Signalling to ERKs	R-HSA-187687	5.04	2	FGF23, KL
Signal Transduction	R-HSA-162582	1.78	2	FGF23, KL

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
FGFR1c and Klotho ligand binding and activation (R-HSA-190374)	-	11.4	0.0	FGF23, KL
PI3K/AKT Signaling in Cancer (R-HSA-2219528)	-	6.56	0.039	FGF23, KL
PI3K Cascade (R-HSA-109704)	-	6.68	0.033	FGF23, KL
FGFR1 ligand binding and activation (R-HSA-190242)	-	8.98	0.001	FGF23, KL
SHC-mediated cascade:FGFR1 (R-HSA-5654688)	-	8.59	0.002	FGF23, KL
Constitutive Signaling by Aberrant PI3K in Cancer (R-HSA-2219530)	-	7.05	0.031	FGF23, KL
Negative regulation of FGFR1 signaling (R-HSA-5654726)	-	7.98	0.005	FGF23, KL
Phospholipase C-mediated cascade: FGFR1 (R-HSA-5654219)	-	7.43	0.031	FGF23, KL

GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
catalytic activity (GO:0003824)	1.05	3	FGF23, GALNT3, KL
transferase activity (GO:0016740)	1.95	3	FGF23, KL, GALNT3
binding (GO:0005488)	0.18	3	FGF23, KL, GALNT3
protein binding (GO:0005515)	0.46	3	FGF23, KL, GALNT3
phosphatidylinositol-4,5-bisphosphate 3-kinase activity (GO:0046934)	5.61	2	FGF23, KL
Ras guanyl-nucleotide exchange factor activity (GO:0005088)	4.31	2	FGF23, KL
growth factor receptor binding (GO:0070851)	4.87	2	FGF23, KL
phosphatidylinositol kinase activity (GO:0052742)	5.81	2	FGF23, KL
transferase activity, transferring phosphorus-containing groups (GO:0016772)	2.77	2	FGF23, KL
kinase activity (GO:0016301)	2.93	2	FGF23, KL
guanyl-nucleotide exchange factor activity (GO:0005085)	4.02	2	FGF23, KL
phosphatidylinositol bisphosphate kinase activity (GO:0052813)	5.56	2	FGF23, KL
phosphatidylinositol 3-kinase activity (GO:0035004)	5.49	2	FGF23, KL
1-phosphatidylinositol-3-kinase activity (GO:0016303)	5.98	2	FGF23, KL
receptor binding (GO:0005102)	2.43	2	FGF23, KL
molecular function regulator (GO:0098772)	2.51	2	FGF23, KL
fibroblast growth factor receptor binding (GO:0005104)	6.41	2	FGF23, KL
phosphotransferase activity, alcohol group as acceptor (GO:0016773)	3.08	2	FGF23, KL

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
extracellular matrix structural constituent (GO:0005201)	NEW	5.37	0.016	FGF23, GALNT3
growth factor receptor binding (GO:0070851)	-	4.87	0.005	FGF23, KL
fibroblast growth factor receptor binding (GO:0005104)	-	6.41	0.0	FGF23, KL

GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
signal transduction (GO:0007165)	1.28	3	FGF23, GALNT3, KL
cell surface receptor signaling pathway (GO:0007166)	2.09	3	FGF23, KL, GALNT3
enzyme linked receptor protein signaling pathway (GO:0007167)	3.24	3	FGF23, KL, GALNT3
transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)	3.54	3	FGF23, KL, GALNT3
fibroblast growth factor receptor signaling pathway (GO:0008543)	5.3	3	FGF23, GALNT3, KL
regulation of biological process (GO:0050789)	0.45	3	FGF23, GALNT3, KL
single-organism process (GO:0044699)	0.48	3	FGF23, KL, GALNT3
cellular protein metabolic process (GO:0044267)	1.63	3	FGF23, GALNT3, KL
single-organism metabolic process (GO:0044710)	1.63	3	FGF23, KL, GALNT3
cellular macromolecule metabolic process (GO:0044260)	0.93	3	FGF23, KL, GALNT3
organic substance metabolic process (GO:0071704)	0.63	3	FGF23, GALNT3, KL
biological regulation (GO:0065007)	0.39	3	FGF23, KL, GALNT3
cellular process (GO:0009987)	0.26	3	FGF23, GALNT3, KL
cellular protein modification process (GO:0006464)	1.79	3	FGF23, GALNT3, KL
regulation of cellular process (GO:0050794)	0.5	3	FGF23, KL, GALNT3
macromolecule modification (GO:0043412)	1.73	3	FGF23, GALNT3, KL
protein modification process (GO:0036211)	1.79	3	FGF23, GALNT3, KL
single-organism cellular process (GO:0044763)	0.65	3	FGF23, KL, GALNT3
metabolic process (GO:0008152)	0.58	3	FGF23, KL, GALNT3
primary metabolic process (GO:0044238)	0.69	3	FGF23, KL, GALNT3
protein metabolic process (GO:0019538)	1.45	3	FGF23, GALNT3, KL
cellular metabolic process (GO:0044237)	0.69	3	FGF23, KL, GALNT3
macromolecule metabolic process (GO:0043170)	0.83	3	FGF23, GALNT3, KL
regulation of phosphate metabolic process (GO:0019220)	2.35	2	FGF23, KL
regulation of primary metabolic process (GO:0080090)	1.08	2	FGF23, KL
regulation of metabolic process (GO:0019222)	1.02	2	FGF23, KL
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway (GO:0090080)	8.12	2	FGF23, KL
positive regulation of response to stimulus (GO:0048584)	2.18	2	FGF23, KL
regulation of response to stimulus (GO:0048583)	1.54	2	FGF23, KL
regulation of bone mineralization (GO:0030500)	5.49	2	FGF23, KL
signal transduction by protein phosphorylation (GO:0023014)	3.79	2	FGF23, KL
single-organism biosynthetic process (GO:0044711)	2.8	2	FGF23, KL
positive regulation of macromolecule metabolic process (GO:0010604)	1.81	2	FGF23, KL
regulation of signal transduction (GO:0009966)	1.84	2	FGF23, KL
positive regulation of signal transduction (GO:0009967)	2.5	2	FGF23, KL
MAPK cascade (GO:0000165)	3.91	2	FGF23, KL
peptidyl-amino acid modification (GO:0018193)	2.98	2	FGF23, GALNT3
positive regulation of molecular function (GO:0044093)	2.23	2	FGF23, KL
positive regulation of biological process (GO:0048518)	1.2	2	FGF23, KL
phosphatidylinositol biosynthetic process (GO:0006661)	4.94	2	FGF23, KL
regulation of macromolecule metabolic process (GO:0060255)	1.08	2	FGF23, KL
phosphatidylinositol metabolic process (GO:0046488)	4.46	2	FGF23, KL
glycerolipid metabolic process (GO:0046486)	3.91	2	FGF23, KL
regulation of phosphorylation (GO:0042325)	2.5	2	FGF23, KL
positive regulation of phosphorylation (GO:0042327)	2.9	2	FGF23, KL
chemical homeostasis (GO:0048878)	2.97	2	FGF23, KL
organophosphate metabolic process (GO:0019637)	3.04	2	FGF23, KL
positive regulation of metabolic process (GO:0009893)	1.74	2	FGF23, KL
inorganic ion homeostasis (GO:0098771)	3.43	2	FGF23, KL
intracellular signal transduction (GO:0035556)	2.39	2	FGF23, KL
organic substance biosynthetic process (GO:1901576)	1.34	2	FGF23, KL
positive regulation of GTPase activity (GO:0043547)	3.28	2	FGF23, KL
positive regulation of hydrolase activity (GO:0051345)	2.91	2	FGF23, KL
phosphatidylinositol phosphorylation (GO:0046854)	5.19	2	FGF23, KL
regulation of molecular function (GO:0065009)	1.78	2	FGF23, KL
regulation of biological quality (GO:0065008)	1.68	2	FGF23, KL
lipid metabolic process (GO:0006629)	2.68	2	FGF23, KL
regulation of developmental process (GO:0050793)	2.1	2	FGF23, KL
regulation of catalytic activity (GO:0050790)	1.97	2	FGF23, KL
regulation of biomineral tissue development (GO:0070167)	5.41	2	FGF23, KL
positive regulation of MAPK cascade (GO:0043410)	3.57	2	FGF23, KL
regulation of multicellular organismal process (GO:0051239)	1.87	2	FGF23, KL
positive regulation of intracellular signal transduction (GO:1902533)	2.95	2	FGF23, KL
regulation of ossification (GO:0030278)	4.53	2	FGF23, KL
regulation of intracellular signal transduction (GO:1902531)	2.31	2	FGF23, KL
organophosphate biosynthetic process (GO:0090407)	3.67	2	FGF23, KL
inositol lipid-mediated signaling (GO:0048017)	4.91	2	FGF23, KL
regulation of hydrolase activity (GO:0051336)	2.53	2	FGF23, KL
phospholipid biosynthetic process (GO:0008654)	4.39	2	FGF23, KL
positive regulation of protein modification process (GO:0031401)	2.7	2	FGF23, KL
phosphorylation (GO:0016310)	2.63	2	FGF23, KL
ion homeostasis (GO:0050801)	3.42	2	FGF23, KL
positive regulation of signaling (GO:0023056)	2.41	2	FGF23, KL
cellular biosynthetic process (GO:0044249)	1.37	2	FGF23, KL
regulation of signaling (GO:0023051)	1.72	2	FGF23, KL
positive regulation of cell communication (GO:0010647)	2.41	2	FGF23, KL
regulation of cell communication (GO:0010646)	1.73	2	FGF23, KL
regulation of GTPase activity (GO:0043087)	3.21	2	FGF23, KL
positive regulation of catalytic activity (GO:0043085)	2.4	2	FGF23, KL
regulation of MAPK cascade (GO:0043408)	3.22	2	FGF23, KL
phosphatidylinositol-mediated signaling (GO:0048015)	4.93	2	FGF23, KL
positive regulation of phosphorus metabolic process (GO:0010562)	2.78	2	FGF23, KL
regulation of protein metabolic process (GO:0051246)	1.93	2	FGF23, KL
positive regulation of protein metabolic process (GO:0051247)	2.43	2	FGF23, KL
lipid phosphorylation (GO:0046834)	5.13	2	FGF23, KL
positive regulation of cellular protein metabolic process (GO:0032270)	2.49	2	FGF23, KL
regulation of protein modification process (GO:0031399)	2.32	2	FGF23, KL
phospholipid metabolic process (GO:0006644)	3.88	2	FGF23, KL
cellular lipid metabolic process (GO:0044255)	2.92	2	FGF23, KL
regulation of phosphatidylinositol 3-kinase signaling (GO:0014066)	4.79	2	FGF23, KL
lipid modification (GO:0030258)	4.37	2	FGF23, KL
regulation of cellular protein metabolic process (GO:0032268)	1.99	2	FGF23, KL
glycerophospholipid biosynthetic process (GO:0046474)	4.62	2	FGF23, KL
glycerophospholipid metabolic process (GO:0006650)	4.13	2	FGF23, KL
positive regulation of cellular metabolic process (GO:0031325)	1.81	2	FGF23, KL
regulation of cellular metabolic process (GO:0031323)	1.07	2	FGF23, KL
homeostatic process (GO:0042592)	2.61	2	FGF23, KL
glycerolipid biosynthetic process (GO:0045017)	4.53	2	FGF23, KL
protein phosphorylation (GO:0006468)	2.89	2	FGF23, KL
positive regulation of phosphate metabolic process (GO:0045937)	2.78	2	FGF23, KL
regulation of phosphorus metabolic process (GO:0051174)	2.35	2	FGF23, KL
biosynthetic process (GO:0009058)	1.32	2	FGF23, KL
phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)	5.84	2	FGF23, KL
lipid biosynthetic process (GO:0008610)	3.49	2	FGF23, KL
carbohydrate metabolic process (GO:0005975)	3.26	2	GALNT3, KL
phosphate-containing compound metabolic process (GO:0006796)	2.16	2	FGF23, KL
regulation of multicellular organismal development (GO:2000026)	2.31	2	FGF23, KL
phosphorus metabolic process (GO:0006793)	2.15	2	FGF23, KL
regulation of protein phosphorylation (GO:0001932)	2.57	2	FGF23, KL
positive regulation of protein phosphorylation (GO:0001934)	2.95	2	FGF23, KL
positive regulation of cellular process (GO:0048522)	1.3	2	FGF23, KL

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
insulin receptor signaling pathway (GO:0008286)	NEW	5.33	0.042	FGF23, KL
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway (GO:0090080)	-	8.12	0.0	FGF23, KL
regulation of biomineral tissue development (GO:0070167)	-	5.41	0.01	FGF23, KL
regulation of bone mineralization (GO:0030500)	-	5.49	0.009	FGF23, KL
phosphatidylinositol-mediated signaling (GO:0048015)	-	4.93	0.036	FGF23, KL
inositol lipid-mediated signaling (GO:0048017)	-	4.91	0.036	FGF23, KL

GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GO	IC	Number of genes with the same GO	Genes
cell part (GO:0044464)	0.11	3	FGF23, KL, GALNT3
extracellular region part (GO:0044421)	1.57	3	FGF23, GALNT3, KL
extracellular organelle (GO:0043230)	1.89	2	GALNT3, KL
extracellular space (GO:0005615)	2.63	2	FGF23, KL
extracellular exosome (GO:0070062)	1.89	2	KL, GALNT3
integral component of membrane (GO:0016021)	1.14	2	GALNT3, KL
membrane (GO:0016020)	0.68	2	GALNT3, KL
cytoplasmic part (GO:0044444)	0.82	2	FGF23, GALNT3
membrane-bounded vesicle (GO:0031988)	1.71	2	GALNT3, KL
intracellular organelle part (GO:0044446)	0.81	2	FGF23, GALNT3
Golgi apparatus part (GO:0044431)	3.0	2	FGF23, GALNT3
extracellular region (GO:0005576)	2.18	2	FGF23, KL
organelle part (GO:0044422)	0.79	2	FGF23, GALNT3
intracellular part (GO:0044424)	0.28	2	FGF23, GALNT3
membrane part (GO:0044425)	0.95	2	GALNT3, KL
extracellular vesicle (GO:1903561)	1.89	2	KL, GALNT3
membrane-bounded organelle (GO:0043227)	0.47	2	KL, GALNT3
organelle (GO:0043226)	0.4	2	KL, GALNT3
intrinsic component of membrane (GO:0031224)	1.13	2	KL, GALNT3
vesicle (GO:0031982)	1.64	2	GALNT3, KL