Disease table of IGA NEPHROPATHY OMIM ID: PS161950

Gene-disease associations table

GeneAssociated with IGA NEPHROPATHY inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
SPRY2ClinVar, OMIMHGNC link13q31.11PS161950
PIGRClinVarHGNC link1q32.11PS161950

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
SPRY2YES4SP1, CREB1, ETS1, TFAP2A0
PIGRYES7AR, IRF1, USF2, RELB, RELA, NFKB1, USF10
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms / NET-GE enrichment (no shared terms)
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
single-organism cellular localization (GO:1902580) 3.162SPRY2, PIGR
cellular process (GO:0009987) 0.262SPRY2, PIGR
regulation of response to stimulus (GO:0048583) 1.542SPRY2, PIGR
cellular component organization (GO:0016043) 1.242SPRY2, PIGR
regulation of cellular process (GO:0050794) 0.52SPRY2, PIGR
single-organism cellular process (GO:0044763) 0.652SPRY2, PIGR
cellular component organization or biogenesis (GO:0071840) 1.222SPRY2, PIGR
single-organism localization (GO:1902578) 2.092SPRY2, PIGR
biological regulation (GO:0065007) 0.392SPRY2, PIGR
localization (GO:0051179) 1.42SPRY2, PIGR
establishment of localization (GO:0051234) 1.482SPRY2, PIGR
regulation of biological process (GO:0050789) 0.452SPRY2, PIGR
single-organism process (GO:0044699) 0.482SPRY2, PIGR
cellular localization (GO:0051641) 2.322SPRY2, PIGR

NET-GE enrichment

Term New enriched termICP valueGenes
epidermal growth factor receptor signaling pathway (GO:0007173) NEW5.720.023SPRY2, PIGR
ERBB signaling pathway (GO:0038127) NEW5.360.024SPRY2, PIGR
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
membrane-bounded organelle (GO:0043227) 0.472SPRY2, PIGR
membrane (GO:0016020) 0.682SPRY2, PIGR
cell part (GO:0044464) 0.112SPRY2, PIGR
plasma membrane (GO:0005886) 1.392SPRY2, PIGR
membrane part (GO:0044425) 0.952SPRY2, PIGR
plasma membrane part (GO:0044459) 1.952SPRY2, PIGR
organelle (GO:0043226) 0.42SPRY2, PIGR

NET-GE enrichment

Term New enriched termICP valueGenes
transport vesicle membrane (GO:0030658) NEW4.860.013SPRY2, PIGR
coated vesicle membrane (GO:0030662) NEW5.00.013SPRY2, PIGR