Gene table of AR : androgen receptor

Gene-disease associations table

Disease ID	Disease name	Source of annotation with AR	OMIM link	Number of associated genes	genes
300068	ANDROGEN INSENSITIVITY SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	AR
PS300633	HYPOSPADIAS	ClinVar, OMIM	link to OMIM	2	AR, MAMLD1
312300	ANDROGEN INSENSITIVITY, PARTIAL	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	AR
313200	SPINAL AND BULBAR MUSCULAR ATROPHY, X-LINKED 1	ClinVar, OMIM	link to OMIM	1	AR
176807	PROSTATE CANCER	OMIM	link to OMIM	15	PTEN, EPHB2, KLF6, AR, HIP1, CD82, ZFHX3, BRCA2, CDH1, CHEK2, MXI1, MAD1L1, HOXB13, MSR1, FGFR4

Download the gene annotation in CSV format

Annotation of the gene AR

Associated genes in ENSEMBL

ENSG00000169083

Associated proteins - SwissProt Accession ID

P10275

Associated PDB IDs

Cytogenetic Band

Xq12

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Pathways in cancer	hsa05200	3.98
Oocyte meiosis	hsa04114	5.91
Prostate cancer	hsa05215	6.11

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Nuclear Receptor transcription pathway	R-HSA-383280	7.31
RHO GTPase Effectors	R-HSA-195258	4.94
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	7.94
Generic Transcription Pathway	R-HSA-212436	3.86
Gene Expression	R-HSA-74160	2.72
RHO GTPases activate PKNs	R-HSA-5625740	7.1
Signaling by Rho GTPases	R-HSA-194315	4.43
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
nucleic acid binding	GO:0003676	1.44
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
molecular transducer activity	GO:0060089	2.32
transcription factor activity, direct ligand regulated sequence-specific DNA binding	GO:0098531	5.87
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
DNA binding	GO:0003677	1.92
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
heterocyclic compound binding	GO:1901363	1.06
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	GO:0004879	5.87
hormone binding	GO:0042562	5.53
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transition metal ion binding	GO:0046914	2.48
zinc ion binding	GO:0008270	2.66
ion binding	GO:0043167	1.36
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
metal ion binding	GO:0046872	1.41
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
cation binding	GO:0043169	1.4
ATPase binding	GO:0051117	5.41
transcription factor binding	GO:0008134	3.46
regulatory region nucleic acid binding	GO:0001067	3.03
lipid binding	GO:0008289	3.26
beta-catenin binding	GO:0008013	5.3
enzyme binding	GO:0019899	2.27
steroid binding	GO:0005496	5.24
	GO:0005497	8.35
protein dimerization activity	GO:0046983	2.72
RNA polymerase II transcription factor binding	GO:0001085	5.08
transcription regulatory region DNA binding	GO:0044212	3.03
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
nucleic acid binding transcription factor activity	GO:0001071	2.65
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
steroid hormone receptor activity	GO:0003707	5.66
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
androgen receptor activity	GO:0004882	8.64
receptor binding	GO:0005102	2.43
chromatin binding	GO:0003682	3.64
receptor activity	GO:0004872	2.32