Disease table of MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY, TYPE A OMIM ID: PS236670

Gene-disease associations table

GeneAssociated with MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY, TYPE A inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
FKRPClinVar, OMIM, HUMSAVARHGNC link19q13.323PS613155, PS253600, PS236670
B3GALNT2ClinVar, OMIM, HUMSAVARHGNC link1q42.31PS236670
B4GAT1ClinVar, OMIM, HUMSAVARHGNC link11q13.21PS236670
LARGE1ClinVar, OMIM, HUMSAVARHGNC link22q12.32PS613155, PS236670
POMGNT1ClinVar, OMIM, HUMSAVARHGNC link1p34.13PS613155, PS253600, PS236670
POMGNT2ClinVar, OMIM, HUMSAVARHGNC link3p22.11PS236670
GMPPBClinVar, OMIM, HUMSAVARHGNC link3p21.313PS613155, PS253600, PS236670
ISPDClinVar, OMIM, HUMSAVARHGNC link7p21.22PS236670, PS253600
DAG1ClinVar, OMIM, HUMSAVARHGNC link3p21.312PS236670, PS253600
FKTNClinVar, OMIM, HUMSAVARHGNC link9q31.24PS236670, PS613155, PS115200, PS253600
POMT1ClinVar, OMIM, HUMSAVARHGNC link9q34.133PS613155, PS253600, PS236670
POMT2ClinVar, OMIM, HUMSAVARHGNC link14q24.33PS613155, PS253600, PS236670
TMEM5ClinVar, OMIM, HUMSAVARHGNC link12q14.21PS236670
POMKClinVar, OMIM, HUMSAVARHGNC link8p11.212PS236670, PS253600

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By sub-band
Shared sub_bandNumber of genes associated with the diseaseGenes associated with the disease
3p21.312GMPPB, DAG1
By band
Shared bandNumber of genes associated with the diseaseGenes associated with the disease
3p212GMPPB, DAG1
By region
Shared regionNumber of genes associated with the diseaseGenes associated with the disease
3p23DAG1, GMPPB, POMGNT2
9q32FKTN, POMT1
By arm
Shared armNumber of genes associated with the diseaseGenes associated with the disease
3p3DAG1, GMPPB, POMGNT2
9q2FKTN, POMT1
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
12B3GALNT2, POMGNT1
33DAG1, GMPPB, POMGNT2
92FKTN, POMT1
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
POMGNT1YES1ZNF2020
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
FKRPPOMGNT1No2HAUS7, SLC39A4
FKRPDAG1No1HLA-DPA1
FKRPFKTNNo1HLA-DPA1
FKRPPOMT1No1SYNE4
FKRPPOMT2No1CD1B
B3GALNT2B4GAT1No1FBXO6
B3GALNT2POMGNT2No3IDS, FBXO6, NRG1
B3GALNT2POMT1No1NRG1
B4GAT1POMGNT2No1FBXO6
POMGNT1POMT1No1POMK
POMGNT1POMKYes2B4GALT3, FAM134C
POMGNT2POMT1No2ATP1B3, NRG1
POMGNT2POMT2No2PTCH1, PON2
DAG1FKTNNo1HLA-DPA1
DAG1POMT1No1HTR3C
DAG1POMT2No1HTR3C
POMT1POMT2No4HTR3C, TMEM92, ATP1B4, CD244
POMT1POMKYes0

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
GMPPBDAG1No1KRAS

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
FKRPDAG1Yesbinding0
POMGNT1FKTNYesbinding0
GMPPBDAG1No-1UBC

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Gene1Gene2InteractionNumber of common interactorsCommon genes in interaction
POMGNT1DAG1Yes2POMGNT1, DAG1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Other types of O-glycan biosynthesishsa005147.723POMGNT1, POMT1, POMT2
Metabolic pathwayshsa011002.492GMPPB, B4GAT1

NET-GE enrichment

Term New enriched termICP valueGenes
Glycan biosynthesis and metabolismNEW4.780.002POMGNT1, POMT1, POMT2, B4GAT1
Other types of O-glycan biosynthesis (hsa00514) -7.720.0POMGNT1, POMT1, POMT2
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
catalytic activity (GO:0003824) 1.0511POMT1, ISPD, B3GALNT2, POMT2, FKRP, POMGNT2, POMGNT1, POMK, GMPPB, B4GAT1, FKTN
transferase activity (GO:0016740) 1.9511POMT1, FKTN, B3GALNT2, POMT2, FKRP, POMGNT2, POMGNT1, POMK, GMPPB, B4GAT1, ISPD
binding (GO:0005488) 0.188POMT1, POMT2, B4GAT1, POMGNT1, POMK, GMPPB, POMGNT2, DAG1
transferase activity, transferring hexosyl groups (GO:0016758) 4.436POMT1, B3GALNT2, POMT2, B4GAT1, POMGNT1, POMGNT2
transferase activity, transferring glycosyl groups (GO:0016757) 4.086POMT1, B3GALNT2, POMT2, B4GAT1, POMGNT1, POMGNT2
cation binding (GO:0043169) 1.44POMT1, POMT2, DAG1, B4GAT1
ion binding (GO:0043167) 1.364POMT1, POMT2, DAG1, B4GAT1
protein binding (GO:0005515) 0.464POMGNT1, DAG1, GMPPB, POMGNT2
acetylglucosaminyltransferase activity (GO:0008375) 5.854POMGNT1, B4GAT1, B3GALNT2, POMGNT2
metal ion binding (GO:0046872) 1.414POMT1, POMT2, DAG1, B4GAT1
UDP-glycosyltransferase activity (GO:0008194) 4.814POMGNT1, B3GALNT2, POMGNT2, B4GAT1
carbohydrate derivative binding (GO:0097367) 2.033POMK, GMPPB, DAG1
transferase activity, transferring phosphorus-containing groups (GO:0016772) 2.773POMK, GMPPB, ISPD
nucleotidyltransferase activity (GO:0016779) 4.812GMPPB, ISPD
purine ribonucleoside triphosphate binding (GO:0035639) 2.222POMK, GMPPB
organic cyclic compound binding (GO:0097159) 1.052POMK, GMPPB
dolichyl-phosphate-mannose-protein mannosyltransferase activity (GO:0004169) 7.952POMT1, POMT2
nucleotide binding (GO:0000166) 1.962POMK, GMPPB
small molecule binding (GO:0036094) 1.892POMK, GMPPB
ribonucleotide binding (GO:0032553) 2.192POMK, GMPPB
purine ribonucleoside binding (GO:0032550) 2.222POMK, GMPPB
nucleoside phosphate binding (GO:1901265) 1.962POMK, GMPPB
ribonucleoside binding (GO:0032549) 2.222POMK, GMPPB
purine ribonucleotide binding (GO:0032555) 2.22POMK, GMPPB
purine nucleotide binding (GO:0017076) 2.192POMK, GMPPB
mannosyltransferase activity (GO:0000030) 6.522POMT1, POMT2
heterocyclic compound binding (GO:1901363) 1.062POMK, GMPPB
purine nucleoside binding (GO:0001883) 2.222POMK, GMPPB
nucleoside binding (GO:0001882) 2.212POMK, GMPPB

NET-GE enrichment

Term New enriched termICP valueGenes
dolichyl-phosphate-mannose-protein mannosyltransferase activity (GO:0004169) -7.950.0POMT1, POMT2
catalytic activity (GO:0003824) -1.050.002POMT1, ISPD, B3GALNT2, POMT2, FKRP, POMGNT2, POMGNT1, POMK, GMPPB, LARGE, FKTN, B4GAT1
transferase activity (GO:0016740) -1.950.0POMT1, ISPD, B3GALNT2, POMT2, FKRP, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, DAG1, B4GAT1
transferase activity, transferring glycosyl groups (GO:0016757) -4.080.0POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, B4GAT1, POMGNT2
acetylglucosaminyltransferase activity (GO:0008375) -5.850.0POMGNT1, B3GALNT2, B4GAT1, POMGNT2, LARGE
transferase activity, transferring hexosyl groups (GO:0016758) -4.430.0POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, B4GAT1, POMGNT2
UDP-glycosyltransferase activity (GO:0008194) -4.810.0POMGNT1, B3GALNT2, POMGNT2, B4GAT1, LARGE
mannosyltransferase activity (GO:0000030) -6.520.014POMT1, POMT2
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
organic substance metabolic process (GO:0071704) 0.6313POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, GMPPB, B4GAT1, ISPD, TMEM5, DAG1
cellular process (GO:0009987) 0.2613POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, GMPPB, B4GAT1, ISPD, TMEM5, DAG1
cellular metabolic process (GO:0044237) 0.6913POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, GMPPB, B4GAT1, ISPD, TMEM5, DAG1
metabolic process (GO:0008152) 0.5813POMT1, FKTN, B3GALNT2, POMT2, FKRP, POMGNT2, POMGNT1, POMK, GMPPB, B4GAT1, ISPD, TMEM5, DAG1
primary metabolic process (GO:0044238) 0.6913POMT1, FKTN, B3GALNT2, POMT2, FKRP, POMGNT2, POMGNT1, POMK, GMPPB, B4GAT1, ISPD, TMEM5, DAG1
cellular protein metabolic process (GO:0044267) 1.6312POMT1, ISPD, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, FKTN, DAG1
single-organism metabolic process (GO:0044710) 1.6312POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, ISPD, DAG1
carbohydrate metabolic process (GO:0005975) 3.2612POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, ISPD, DAG1
protein glycosylation (GO:0006486) 4.212POMT1, ISPD, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, FKTN, DAG1
cellular macromolecule metabolic process (GO:0044260) 0.9312POMT1, ISPD, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, TMEM5, POMGNT2, FKTN, DAG1
protein metabolic process (GO:0019538) 1.4512POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, ISPD, DAG1
glycosylation (GO:0070085) 4.1612POMT1, ISPD, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, FKTN, DAG1
cellular protein modification process (GO:0006464) 1.7912POMT1, ISPD, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, FKTN, DAG1
macromolecule metabolic process (GO:0043170) 0.8312POMT1, ISPD, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, FKTN, DAG1
macromolecule modification (GO:0043412) 1.7312POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, ISPD, DAG1
macromolecule glycosylation (GO:0043413) 4.212POMT1, ISPD, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, TMEM5, POMGNT2, FKTN, DAG1
single-organism cellular process (GO:0044763) 0.6512POMT1, ISPD, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, TMEM5, POMGNT2, FKTN, DAG1
protein modification process (GO:0036211) 1.7912POMT1, ISPD, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, FKTN, DAG1
single-organism carbohydrate metabolic process (GO:0044723) 3.4212POMT1, FKTN, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, TMEM5, POMGNT2, ISPD, DAG1
protein O-linked glycosylation (GO:0006493) 5.1312POMT1, FKTN, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, ISPD, DAG1
single-organism process (GO:0044699) 0.4812POMT1, ISPD, B3GALNT2, POMT2, POMK, POMGNT2, POMGNT1, FKRP, TMEM5, B4GAT1, FKTN, DAG1
protein mannosylation (GO:0035268) 6.738POMT1, FKTN, POMT2, B4GAT1, FKRP, TMEM5, POMGNT2, ISPD
protein O-linked mannosylation (GO:0035269) 7.098POMT1, FKTN, POMT2, POMGNT2, FKRP, TMEM5, B4GAT1, ISPD
mannosylation (GO:0097502) 6.268POMT1, FKTN, POMT2, POMGNT2, FKRP, TMEM5, B4GAT1, ISPD
cellular biosynthetic process (GO:0044249) 1.376POMT1, POMT2, B4GAT1, FKRP, GMPPB, ISPD
biosynthetic process (GO:0009058) 1.326POMT1, POMT2, B4GAT1, FKRP, GMPPB, ISPD
organic substance biosynthetic process (GO:1901576) 1.346POMT1, POMT2, B4GAT1, FKRP, GMPPB, ISPD
developmental process (GO:0032502) 1.365POMT1, DAG1, POMT2, POMK, FKTN
carbohydrate derivative biosynthetic process (GO:1901137) 3.735POMT2, POMT1, GMPPB, FKRP, B4GAT1
carbohydrate derivative metabolic process (GO:1901135) 3.075POMT2, POMT1, GMPPB, FKRP, B4GAT1
anatomical structure development (GO:0048856) 1.585POMT1, DAG1, POMT2, POMK, FKTN
movement of cell or subcellular component (GO:0006928) 2.615DAG1, POMGNT2, POMK, B4GAT1, ISPD
single-organism developmental process (GO:0044767) 1.495POMT1, POMK, POMT2, DAG1, FKTN
multicellular organismal process (GO:0032501) 1.454POMT1, POMK, POMT2, DAG1
single-multicellular organism process (GO:0044707) 1.784POMT1, POMK, POMT2, DAG1
regulation of signal transduction (GO:0009966) 1.844POMT1, POMT2, DAG1, FKTN
regulation of response to stimulus (GO:0048583) 1.544POMT1, POMT2, DAG1, FKTN
regulation of cellular process (GO:0050794) 0.54POMT1, POMT2, DAG1, FKTN
macromolecule biosynthetic process (GO:0009059) 1.614POMT1, POMT2, FKRP, B4GAT1
biological regulation (GO:0065007) 0.394POMT1, POMT2, DAG1, FKTN
cellular macromolecule biosynthetic process (GO:0034645) 1.664POMT1, POMT2, FKRP, B4GAT1
regulation of signaling (GO:0023051) 1.724POMT1, POMT2, DAG1, FKTN
regulation of cell communication (GO:0010646) 1.734POMT1, POMT2, DAG1, FKTN
regulation of biological process (GO:0050789) 0.454POMT1, POMT2, DAG1, FKTN
regulation of response to stress (GO:0080134) 2.533POMT1, POMT2, FKTN
regulation of cellular response to stress (GO:0080135) 3.43POMT1, POMT2, FKTN
axon guidance (GO:0007411) 4.443DAG1, B4GAT1, ISPD
neuron projection guidance (GO:0097485) 4.433DAG1, B4GAT1, ISPD
glycoprotein metabolic process (GO:0009100) 5.233POMT1, POMT2, FKRP
glycoprotein biosynthetic process (GO:0009101) 5.863POMT1, POMT2, FKRP
regulation of MAPK cascade (GO:0043408) 3.222DAG1, FKTN
regulation of phosphate metabolic process (GO:0019220) 2.352DAG1, FKTN
regulation of primary metabolic process (GO:0080090) 1.082DAG1, FKTN
regulation of metabolic process (GO:0019222) 1.022DAG1, FKTN
negative regulation of response to stimulus (GO:0048585) 2.522DAG1, FKTN
negative regulation of cellular metabolic process (GO:0031324) 2.012DAG1, FKTN
regulation of cellular metabolic process (GO:0031323) 1.072DAG1, FKTN
cell wall macromolecule metabolic process (GO:0044036) 7.652POMT1, POMT2
nitrogen compound metabolic process (GO:0006807) 1.132GMPPB, B4GAT1
neuron migration (GO:0001764) 5.02POMK, POMGNT2
negative regulation of cell communication (GO:0010648) 2.662DAG1, FKTN
negative regulation of metabolic process (GO:0009892) 1.932DAG1, FKTN
multicellular organism development (GO:0007275) 2.542POMT1, POMT2
cellular component organization or biogenesis (GO:0071840) 1.222POMT1, DAG1
cell wall macromolecule biosynthetic process (GO:0044038) 8.342POMT1, POMT2
negative regulation of protein metabolic process (GO:0051248) 2.822DAG1, FKTN
single-organism biosynthetic process (GO:0044711) 2.82B4GAT1, ISPD
negative regulation of macromolecule metabolic process (GO:0010605) 2.012DAG1, FKTN
negative regulation of signal transduction (GO:0009968) 2.752DAG1, FKTN
mannoprotein biosynthetic process (GO:0006057) 8.342POMT1, POMT2
mannoprotein metabolic process (GO:0006056) 8.342POMT1, POMT2
negative regulation of phosphorus metabolic process (GO:0010563) 3.452DAG1, FKTN
regulation of protein metabolic process (GO:0051246) 1.932DAG1, FKTN
cellular component organization (GO:0016043) 1.242POMT1, DAG1
animal organ development (GO:0048513) 2.532POMK, FKTN
negative regulation of MAPK cascade (GO:0043409) 4.742DAG1, FKTN
extracellular structure organization (GO:0043062) 4.02POMT1, DAG1
negative regulation of biological process (GO:0048519) 1.332DAG1, FKTN
cell migration (GO:0016477) 3.122POMK, POMGNT2
locomotion (GO:0040011) 2.912POMK, POMGNT2
negative regulation of phosphate metabolic process (GO:0045936) 3.452DAG1, FKTN
regulation of macromolecule metabolic process (GO:0060255) 1.082DAG1, FKTN
regulation of protein modification process (GO:0031399) 2.322DAG1, FKTN
regulation of phosphorus metabolic process (GO:0051174) 2.352DAG1, FKTN
negative regulation of phosphorylation (GO:0042326) 3.72DAG1, FKTN
proteolysis (GO:0006508) 2.732DAG1, FKRP
negative regulation of intracellular signal transduction (GO:1902532) 3.632DAG1, FKTN
cellular carbohydrate metabolic process (GO:0044262) 4.742POMK, B4GAT1
regulation of intracellular signal transduction (GO:1902531) 2.312DAG1, FKTN
cell wall mannoprotein biosynthetic process (GO:0000032) 8.342POMT1, POMT2
chain elongation of O-linked mannose residue (GO:0044845) 8.342POMT1, POMT2
regulation of phosphorylation (GO:0042325) 2.52DAG1, FKTN
negative regulation of cellular protein metabolic process (GO:0032269) 2.882DAG1, FKTN
regulation of cellular protein metabolic process (GO:0032268) 1.992DAG1, FKTN
cell wall glycoprotein biosynthetic process (GO:0031506) 8.342POMT1, POMT2
cell motility (GO:0048870) 3.022POMK, POMGNT2
negative regulation of protein modification process (GO:0031400) 3.42DAG1, FKTN
cellular component macromolecule biosynthetic process (GO:0070589) 8.342POMT1, POMT2
extracellular matrix organization (GO:0030198) 4.012POMT1, DAG1
regulation of endoplasmic reticulum unfolded protein response (GO:1900101) 6.42POMT1, POMT2
negative regulation of protein phosphorylation (GO:0001933) 3.792DAG1, FKTN
regulation of protein phosphorylation (GO:0001932) 2.572DAG1, FKTN
negative regulation of signaling (GO:0023057) 2.652DAG1, FKTN
negative regulation of cellular process (GO:0048523) 1.412DAG1, FKTN

NET-GE enrichment

Term New enriched termICP valueGenes
cellular protein metabolic process (GO:0044267) -1.630.001POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, ISPD, B4GAT1
carbohydrate metabolic process (GO:0005975) -3.260.0POMT1, B3GALNT2, POMT2, POMGNT2, POMGNT1, POMK, GMPPB, LARGE, ISPD, DAG1, B4GAT1
protein glycosylation (GO:0006486) -4.20.0POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, ISPD, B4GAT1
carbohydrate derivative biosynthetic process (GO:1901137) -3.730.037FKRP, GMPPB, B4GAT1, LARGE
glycosylation (GO:0070085) -4.160.0POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, ISPD, B4GAT1
mannosylation (GO:0097502) -6.260.001POMT1, POMT2, ISPD
cellular protein modification process (GO:0006464) -1.790.0POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, ISPD, B4GAT1
protein metabolic process (GO:0019538) -1.450.0POMT1, B3GALNT2, POMT2, FKRP, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, ISPD, DAG1, B4GAT1
macromolecule modification (GO:0043412) -1.730.0POMT1, B3GALNT2, POMT2, POMGNT2, POMGNT1, POMK, GMPPB, LARGE, ISPD, B4GAT1
macromolecule glycosylation (GO:0043413) -4.20.0POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, ISPD, B4GAT1
protein modification process (GO:0036211) -1.790.0POMT1, B3GALNT2, POMT2, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, ISPD, B4GAT1
single-organism carbohydrate metabolic process (GO:0044723) -3.420.0POMT1, B3GALNT2, POMT2, POMGNT2, POMGNT1, POMK, GMPPB, LARGE, ISPD, B4GAT1
protein O-linked glycosylation (GO:0006493) -5.130.0POMT1, B3GALNT2, POMT2, POMGNT2, POMGNT1, POMK, ISPD
protein mannosylation (GO:0035268) -6.730.0POMT1, POMT2, ISPD
protein O-linked mannosylation (GO:0035269) -7.090.0POMT1, POMT2, ISPD
glycoprotein biosynthetic process (GO:0009101) -5.860.007DAG1, FKRP, LARGE
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
intracellular membrane-bounded organelle (GO:0043231) 0.612POMT1, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, TMEM5, DAG1
cell part (GO:0044464) 0.1112POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, GMPPB, POMGNT2, FKTN, TMEM5, DAG1
intracellular organelle (GO:0043229) 0.5112POMT1, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, TMEM5, DAG1
cytoplasmic part (GO:0044444) 0.8212POMT1, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, TMEM5, DAG1
intracellular part (GO:0044424) 0.2812POMT1, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, TMEM5, DAG1
membrane-bounded organelle (GO:0043227) 0.4712POMT1, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, TMEM5, DAG1
organelle (GO:0043226) 0.412POMT1, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, TMEM5, DAG1
integral component of membrane (GO:0016021) 1.1411POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, TMEM5, POMGNT2, FKTN, DAG1
membrane (GO:0016020) 0.6811POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, TMEM5, POMGNT2, FKTN, DAG1
intracellular organelle part (GO:0044446) 0.8111POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, TMEM5, POMGNT2, FKTN, DAG1
organelle part (GO:0044422) 0.7911POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, TMEM5, POMGNT2, FKTN, DAG1
membrane part (GO:0044425) 0.9511POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, TMEM5, POMGNT2, FKTN, DAG1
intrinsic component of membrane (GO:0031224) 1.1311POMT1, B3GALNT2, POMT2, FKRP, B4GAT1, POMGNT1, POMK, TMEM5, POMGNT2, FKTN, DAG1
endoplasmic reticulum (GO:0005783) 2.567POMT1, B3GALNT2, POMT2, FKRP, POMGNT2, POMK, FKTN
Golgi apparatus (GO:0005794) 2.76B3GALNT2, B4GAT1, POMGNT1, FKRP, TMEM5, FKTN
bounding membrane of organelle (GO:0098588) 2.396B3GALNT2, B4GAT1, POMGNT1, FKRP, TMEM5, FKTN
Golgi apparatus part (GO:0044431) 3.06B3GALNT2, B4GAT1, POMGNT1, FKRP, TMEM5, FKTN
organelle membrane (GO:0031090) 1.976B3GALNT2, B4GAT1, POMGNT1, FKRP, TMEM5, FKTN
Golgi membrane (GO:0000139) 3.286B3GALNT2, B4GAT1, POMGNT1, FKRP, TMEM5, FKTN
extracellular region part (GO:0044421) 1.575FKRP, DAG1, GMPPB, B4GAT1, FKTN
protein complex (GO:0043234) 1.514FKRP, POMT1, POMT2, DAG1
macromolecular complex (GO:0032991) 1.354FKRP, POMT1, POMT2, DAG1
vesicle (GO:0031982) 1.644POMT1, GMPPB, DAG1, B4GAT1
membrane protein complex (GO:0098796) 2.844FKRP, POMT1, POMT2, DAG1
membrane-bounded vesicle (GO:0031988) 1.714POMT1, GMPPB, DAG1, B4GAT1
endoplasmic reticulum part (GO:0044432) 2.734POMT1, POMT2, POMK, POMGNT2
endoplasmic reticulum membrane (GO:0005789) 2.954POMT1, POMT2, POMK, POMGNT2
plasma membrane part (GO:0044459) 1.953FKRP, TMEM5, DAG1
extracellular vesicle (GO:1903561) 1.893DAG1, GMPPB, B4GAT1
extracellular organelle (GO:0043230) 1.893DAG1, GMPPB, B4GAT1
extracellular exosome (GO:0070062) 1.893DAG1, GMPPB, B4GAT1
extracellular space (GO:0005615) 2.633DAG1, FKRP, FKTN
cytoplasm (GO:0005737) 1.012DAG1, GMPPB
dolichyl-phosphate-mannose-protein mannosyltransferase complex (GO:0031502) 8.422POMT1, POMT2
mannosyltransferase complex (GO:0031501) 7.722POMT1, POMT2
sarcolemma (GO:0042383) 5.22DAG1, FKRP
catalytic complex (GO:1902494) 2.92POMT1, POMT2
nucleus (GO:0005634) 1.072DAG1, FKTN
plasma membrane protein complex (GO:0098797) 3.552DAG1, FKRP
dystrophin-associated glycoprotein complex (GO:0016010) 7.032DAG1, FKRP
extracellular region (GO:0005576) 2.182DAG1, FKRP
transferase complex (GO:1990234) 3.322POMT1, POMT2
plasma membrane (GO:0005886) 1.392DAG1, FKRP
glycoprotein complex (GO:0090665) 7.032DAG1, FKRP

NET-GE enrichment

Term New enriched termICP valueGenes
organelle membrane (GO:0031090) -1.970.024POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, GMPPB, POMGNT2, FKTN, DAG1
cytoplasmic part (GO:0044444) -0.820.01POMT1, B3GALNT2, POMT2, FKRP, LARGE, POMGNT1, POMK, GMPPB, POMGNT2, FKTN, DAG1, B4GAT1
integral component of membrane (GO:0016021) -1.140.0POMT1, B3GALNT2, POMT2, FKRP, LARGE, POMGNT1, POMK, TMEM5, B4GAT1, FKTN, DAG1, POMGNT2
dystrophin-associated glycoprotein complex (GO:0016010) -7.030.004DAG1, FKRP
Golgi membrane (GO:0000139) -3.280.003B3GALNT2, B4GAT1, POMGNT1, FKRP, FKTN, DAG1
intracellular organelle part (GO:0044446) -0.810.042POMT1, B3GALNT2, POMT2, POMK, LARGE, POMGNT1, FKRP, B4GAT1, FKTN, DAG1, POMGNT2
Golgi apparatus part (GO:0044431) -3.00.001B3GALNT2, B4GAT1, POMGNT1, FKRP, LARGE, FKTN, DAG1
membrane part (GO:0044425) -0.950.003POMT1, B3GALNT2, POMT2, FKRP, LARGE, POMGNT1, POMK, TMEM5, B4GAT1, FKTN, DAG1, POMGNT2
bounding membrane of organelle (GO:0098588) -2.390.0POMT1, B3GALNT2, POMT2, POMK, B4GAT1, POMGNT1, FKRP, POMGNT2, FKTN
endoplasmic reticulum (GO:0005783) -2.560.012FKRP, B3GALNT2, POMT1, FKTN, POMGNT2