Gene table of ADAR : adenosine deaminase, RNA specific

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ADAR	OMIM link	Number of associated genes	genes
PS179850	RETICULATE PIGMENT DISORDERS	ClinVar, OMIM, HUMSAVAR	link to OMIM	5	ADAM10, POFUT1, POGLUT1, ADAR, KRT5
PS225750	AICARDI-GOUTIERES SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	7	IFIH1, RNASEH2B, RNASEH2C, RNASEH2A, ADAR, TREX1, SAMHD1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Influenza A	hsa05164	5.21
Measles	hsa05162	5.6
Cytosolic DNA-sensing pathway	hsa04623	6.79

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Gene Expression	R-HSA-74160	2.72
mRNA Editing: A to I Conversion	R-HSA-75064	11.98
Immune System	R-HSA-168256	2.37
C6 deamination of adenosine	R-HSA-75102	11.98
Cytokine Signaling in Immune system	R-HSA-1280215	3.74
mRNA Editing	R-HSA-75072	10.98
Interferon alpha/beta signaling	R-HSA-909733	6.04
Interferon Signaling	R-HSA-913531	4.95
Formation of editosomes by ADAR proteins	R-HSA-77042	11.98

Associated GO terms for Molecular function

GO term	GO ID	GO IC
hydrolase activity	GO:0016787	1.9
poly(A) RNA binding	GO:0044822	2.69
protein binding	GO:0005515	0.46
cation binding	GO:0043169	1.4
organic cyclic compound binding	GO:0097159	1.05
adenosine deaminase activity	GO:0004000	7.34
heterocyclic compound binding	GO:1901363	1.06
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	GO:0016814	6.21
ion binding	GO:0043167	1.36
	GO:0003726	8.64
catalytic activity	GO:0003824	1.05
deaminase activity	GO:0019239	6.24
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
metal ion binding	GO:0046872	1.41
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	GO:0016810	4.76
RNA binding	GO:0003723	2.36