| Disease ID | Disease name | Source of annotation with EPO | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS603933 | MICROVASCULAR COMPLICATIONS OF DIABETES | ClinVar, OMIM | link to OMIM | 7 | EPO, ACE, PON1, IL1RN, SOD2, HFE, VEGFA |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| HIF-1 signaling pathway | hsa04066 | 5.9 |
| Jak-STAT signaling pathway | hsa04630 | 5.44 |
| Hematopoietic cell lineage | hsa04640 | 6.18 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Cellular response to hypoxia | R-HSA-2262749 | 8.4 |
| Regulation of Hypoxia-inducible Factor (HIF) by oxygen | R-HSA-1234174 | 8.4 |
| Cellular responses to stress | R-HSA-2262752 | 4.56 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 9.81 |
| GO term | GO ID | GO IC |
|---|---|---|
| hormone activity | GO:0005179 | 4.95 |
| cytokine receptor binding | GO:0005126 | 4.14 |
| kinase regulator activity | GO:0019207 | 4.5 |
| protein kinase regulator activity | GO:0019887 | 4.6 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| kinase activator activity | GO:0019209 | 5.58 |
| erythropoietin receptor binding | GO:0005128 | 9.05 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| molecular function regulator | GO:0098772 | 2.51 |
| protein kinase activator activity | GO:0030295 | 5.68 |
| enzyme activator activity | GO:0008047 | 3.56 |