| Disease ID | Disease name | Source of annotation with VEGFA | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS603933 | MICROVASCULAR COMPLICATIONS OF DIABETES | ClinVar, OMIM | link to OMIM | 7 | EPO, ACE, PON1, IL1RN, SOD2, HFE, VEGFA |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Renal cell carcinoma | hsa05211 | 6.6 |
| VEGF signaling pathway | hsa04370 | 6.77 |
| Proteoglycans in cancer | hsa05205 | 5.02 |
| Rheumatoid arthritis | hsa05323 | 6.05 |
| MicroRNAs in cancer | hsa05206 | 5.38 |
| Pathways in cancer | hsa05200 | 3.98 |
| Pancreatic cancer | hsa05212 | 6.56 |
| Rap1 signaling pathway | hsa04015 | 4.97 |
| Ras signaling pathway | hsa04014 | 4.9 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| Focal adhesion | hsa04510 | 4.92 |
| HIF-1 signaling pathway | hsa04066 | 5.9 |
| Bladder cancer | hsa05219 | 7.38 |
| mTOR signaling pathway | hsa04150 | 6.72 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.7 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 9.98 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 5.07 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 9.81 |
| Platelet degranulation | R-HSA-114608 | 6.68 |
| Cellular response to hypoxia | R-HSA-2262749 | 8.4 |
| Signaling by VEGF | R-HSA-194138 | 4.66 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 9.98 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.59 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 7.89 |
| Cellular responses to stress | R-HSA-2262752 | 4.56 |
| Regulation of Hypoxia-inducible Factor (HIF) by oxygen | R-HSA-1234174 | 8.4 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Axon guidance | R-HSA-422475 | 3.93 |
| EPH-Ephrin signaling | R-HSA-2682334 | 6.43 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Developmental Biology | R-HSA-1266738 | 3.48 |
| GO term | GO ID | GO IC |
|---|---|---|
| cytokine receptor binding | GO:0005126 | 4.14 |
| chemoattractant activity | GO:0042056 | 6.48 |
| cytokine activity | GO:0005125 | 4.34 |
| extracellular matrix binding | GO:0050840 | 5.79 |
| platelet-derived growth factor receptor binding | GO:0005161 | 7.1 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| molecular function regulator | GO:0098772 | 2.51 |
| sulfur compound binding | GO:1901681 | 4.32 |
| vascular endothelial growth factor receptor 1 binding | GO:0043183 | 9.05 |
| growth factor activity | GO:0008083 | 4.66 |
| vascular endothelial growth factor receptor 2 binding | GO:0043184 | 7.95 |
| protein dimerization activity | GO:0046983 | 2.72 |
| receptor activator activity | GO:0030546 | 6.27 |
| fibronectin binding | GO:0001968 | 6.41 |
| protein homodimerization activity | GO:0042803 | 3.16 |
| vascular endothelial growth factor receptor binding | GO:0005172 | 7.54 |
| receptor agonist activity | GO:0048018 | 6.97 |
| heparin binding | GO:0008201 | 4.68 |
| neuropilin binding | GO:0038191 | 7.03 |
| growth factor receptor binding | GO:0070851 | 4.87 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| glycosaminoglycan binding | GO:0005539 | 4.42 |
| identical protein binding | GO:0042802 | 2.63 |
| protein binding | GO:0005515 | 0.46 |
| receptor regulator activity | GO:0030545 | 5.91 |
| receptor binding | GO:0005102 | 2.43 |
| protein heterodimerization activity | GO:0046982 | 3.64 |